| Not Yet Recruiting | Permanent Supportive Housing Overdose Prevention-2 Study NCT07214519 | NYU Langone Health | N/A |
| Not Yet Recruiting | Improving HIV Prevention and Substance Use Post-Sexual Assault Services NCT07225062 | The University of Texas Health Science Center, Houston | N/A |
| Not Yet Recruiting | A Social Network Approach to Improve HIV Prevention and Substance Use Treatment For People Who Use Drugs NCT07409350 | NYU Langone Health | N/A |
| Not Yet Recruiting | Home Visitation Enhancing Linkages Project in Kansas NCT06624332 | The National Center on Addiction and Substance Abuse at Columbia University | N/A |
| Not Yet Recruiting | Project REACH: A Comprehensive Telehealth Intervention at Syringe Service Programs to Engage People Who Use Dr NCT07433712 | University of Minnesota | N/A |
| Not Yet Recruiting | Feasibility of Incorporating a Standardized Substance Use Measure With Linked-Brief Intervention Into Routine NCT07516301 | St. Jude Children's Research Hospital | N/A |
| Recruiting | Neuroimaging of Adolescent Cannabis Use Treatment NCT07340554 | Indiana University | N/A |
| Recruiting | Finding Emotional Empowerment and Lifelong Strength NCT07378254 | Rutgers, The State University of New Jersey | N/A |
| Not Yet Recruiting | Assessments of Obsessive-compulsive Symptoms in Patients With Substances Use Disorder NCT07395453 | Assiut University | — |
| Not Yet Recruiting | Mindfulness-Based Substance Use Prevention (MINDS-UP) NCT06593470 | New York State Psychiatric Institute | N/A |
| Not Yet Recruiting | Options for Navigating Talking About Risk and Adolescent Choices NCT06754527 | Rhode Island Hospital | N/A |
| Suspended | The Development of a Brief Parent-Child Substance Use Educational Intervention for Black Families NCT05455203 | Yale University | N/A |
| Enrolling By Invitation | Cytisine vs Nicotine Replacement Therapy NCT03249428 | Ottawa Hospital Research Institute | N/A |
| Not Yet Recruiting | The Development and Evaluation of a Culturally Grounded ENDS Intervention for Rural Hawaiian Youth NCT06929520 | University of Hawaii | N/A |
| Recruiting | Neurobehavioral Signatures of Sign- and Goal-Tracking in Emerging Adults: Translation of a Preclinical Model NCT07094061 | University of Michigan | N/A |
| Recruiting | Gii'Igoshimong: Sitting With Your First Family NCT07075081 | Johns Hopkins Bloomberg School of Public Health | Phase 2 |
| Withdrawn | A Brief Intervention for Young Adult Substance Users With Interpersonal Trauma NCT07118826 | Western Kentucky University | N/A |
| Recruiting | Adaptation and Evaluation of Bright Horizons NCT05743699 | Johns Hopkins Bloomberg School of Public Health | N/A |
| Recruiting | An Evaluation of the Pink Cloud Application in Post- Treatment Substance Use Disorder Support NCT07042451 | Loyola Marymount University | N/A |
| Recruiting | The Hastiin Bidziil (Strong Man) Intervention NCT06559774 | Johns Hopkins Bloomberg School of Public Health | N/A |
| Recruiting | Integrating Sexual Pleasure Into Harm Reduction Services for Men Who Have Sex With Men and Transgender Persons NCT07509853 | Institute of HIV Research and Innovation Foundation, Thailand | N/A |
| Recruiting | Peer Behavioral Activation Utilization to Improve Substance Use and HIV Outcomes in People Receiving Long Acti NCT06501781 | University of Maryland, Baltimore | N/A |
| Recruiting | Health Surveillance at Constructor University Bremen (CUB) and Among HAW-Hamburg Employees NCT06899308 | Jacobs University Bremen gGmbH | — |
| Recruiting | Host Led Harm Reduction Approach Among Men Who Have Sex With Men Who Engaged in Chemsex in Bangkok, Thailand: NCT07512869 | Institute of HIV Research and Innovation Foundation, Thailand | — |
| Not Yet Recruiting | Expanding Access to mTBI Treatment for Veterans and Service Members With Co-occurring Substance Use NCT06620900 | Shepherd Center, Atlanta GA | N/A |
| Recruiting | Collaborative Care for Polysubstance Use in Primary Care Settings (Co-Care) NCT06116266 | NYU Langone Health | N/A |
| Recruiting | Native Spirit: Significant Aim 3: Intervention NCT06785311 | Arizona State University | N/A |
| Recruiting | The Collaborative Care PrTNER Study NCT06585631 | Children's Hospital of Philadelphia | N/A |
| Not Yet Recruiting | Brief Virtual Mindfulness-based Group Intervention with Social Support for Perinatal Individuals NCT05144893 | Oregon Health and Science University | N/A |
| Not Yet Recruiting | Substance Use Screening to Encourage Behavior Change Among Young People in Primary Care NCT04146714 | Prof. Dagmar M. Haller | N/A |
| Recruiting | Teen Health Choices & Wellness NCT06822569 | Brown University | N/A |
| Completed | Web-based Mind-body Program for Comorbid Nontraumatic Upper-extremity Condition and Risky Substance Use NCT06366633 | Jafar Bakhshaie | N/A |
| Recruiting | Substance Use Treatment and Its Role in Supporting Social Cognition NCT06535919 | Nova Southeastern University | — |
| Recruiting | Open-Label Psilocybin Study in Transdiagnostic Population NCT06442423 | Yale University | Phase 1 |
| Not Yet Recruiting | The Feasibility of the OpiVenture Program for Clients Undergoing Opioid Agonist Therapy NCT06211972 | Dalhousie University | N/A |
| Recruiting | Pre-exposure Prophylaxis (PrEP) Uptake and Adherence Intervention for Women with Trauma-related Conditions NCT06558825 | The University of Texas Health Science Center, Houston | N/A |
| Recruiting | Peer Education for Gender Inclusion and Substance Use in Southern Africa NCT06489899 | University Hospital, Basel, Switzerland | N/A |
| Recruiting | Women Focused Encounters for Resilience Independence Strength and Eudaimonia NCT06216600 | University of California, San Diego | N/A |
| Recruiting | M2VA Pain Care Pathway NCT06526143 | Yale University | N/A |
| Active Not Recruiting | The STop UNhealthy Substance Use Now Trial NCT06524232 | Ohio State University | N/A |
| Recruiting | Ketamine for Methamphetamine Use Disorder NCT06496750 | University of Texas Southwestern Medical Center | Phase 2 |
| Not Yet Recruiting | Walk-in Therapy in Low Barrier Primary Care NCT06552325 | University of Washington | N/A |
| Recruiting | J-RISE: Relevant Implementation Strategies to Eliminate the Social and Structural Barriers to HIV Services Amo NCT06477588 | University of Chicago | N/A |
| Completed | Developing a Digital Intervention to Prevent Risky Health Behaviors NCT06538922 | University of Vermont | N/A |
| Completed | Personally-Tailored Opioid-overdose and Medication for Opioid Use Disorder (MOUD) Education (TOME) for Pregnan NCT06262347 | T. John Winhusen, PhD | N/A |
| Recruiting | Single Session Narrative Therapy Study NCT06479980 | University of Washington | N/A |
| Recruiting | Couples Motivational Interviewing to Reduce Drug Use and HIV Risk in Vulnerable Male Couples NCT06307977 | Hunter College of City University of New York | N/A |
| Recruiting | Cultural Adaptation of Drug Treatment for DJJ Youth NCT06003725 | University of California, San Francisco | N/A |
| Recruiting | Pre-implementation Study to Develop Trans-tailored Services for Transgender Persons in Relation to chemsEX NCT07505875 | Institute of HIV Research and Innovation Foundation, Thailand | — |
| Recruiting | Recovery Finance: Financial Health and Mental Health After Incarceration NCT06914856 | Yale University | N/A |
| Completed | Collaborating to Implement Cross-System Interventions in Child Welfare and Substance Use NCT03931005 | Ohio State University | N/A |
| Active Not Recruiting | Novel Prevention Intervention Program to Reduce Risky Patterns of Substance Use Among Emerging Adults NCT06287203 | Rutgers, The State University of New Jersey | N/A |
| Unknown | Feasibility and Acceptability of a Telehealth Intervention Among Women With Perinatal Mental Health NCT05832424 | Boise State University | N/A |
| Completed | Organization-level Youth Engagement Approach for Substance Misuse Prevention NCT05736211 | Wake Forest University Health Sciences | N/A |
| Recruiting | Primary Connections for Youth and Families NCT05964010 | The National Center on Addiction and Substance Abuse at Columbia University | N/A |
| Active Not Recruiting | FostrSpace-CASA R61/R33 NCT06875323 | University of California, San Francisco | N/A |
| Completed | Feasibility and Acceptability of a Stigma Text Message Intervention for People Who Use Drugs NCT06281548 | University of North Carolina, Chapel Hill | N/A |
| Recruiting | Adverse Adolescent Pathways to Substance Use NCT06977178 | University of North Carolina, Chapel Hill | N/A |
| Recruiting | Adolescent Screening and Personalized Intervention Resource for Enhancement of Behavioral Health and Substance NCT06306287 | Oregon Research Institute | N/A |
| Active Not Recruiting | BrotherlyACT: A Tech-Enhanced Violence and Substance Use Intervention for Black Boys and Young Men NCT06359990 | Rush University Medical Center | N/A |
| Recruiting | The Implementation of a Trans-tailored Harm Reduction Service for Transgender Persons in Relation to chemsEX a NCT07512856 | Institute of HIV Research and Innovation Foundation, Thailand | N/A |
| Recruiting | Journey of Transformation Curriculum for Native American Youth NCT05731713 | University of Washington | N/A |
| Completed | Preoperative Toxicological Screening on Perioperative Anesthetic Management NCT07100314 | General Committee of Teaching Hospitals and Institutes, Egypt | — |
| Active Not Recruiting | Intervention for Virologic Suppression in Youth NCT05877729 | University of California, San Francisco | N/A |
| Recruiting | A Randomized Clinical Trial of a Novel Drug Education and Diversion Program (iDECIDE) for Middle and High Scho NCT06115746 | Massachusetts General Hospital | N/A |
| Unknown | Effect Of Art Therapy Applied to Individuals With Substance Use Subject to Supervised Release NCT06057961 | Mersin University | N/A |
| Unknown | It´s Up To You: Update and Digitalization of a Universal School-based Prevention Intervention for Drug Initiat NCT05950074 | Instituto Europeo de Estudios en Prevención | N/A |
| Recruiting | Optimizing Mental Health for Infants Exposed to Early Adversity: A Comparison of Breaking the Cycle and Maxxin NCT05768815 | University of Ottawa | N/A |
| Recruiting | Parenting in 2 Worlds Multisite Trial NCT06324318 | Arizona State University | Phase 2 |
| Active Not Recruiting | Rapid Adaptation to Prevent Drug Use NCT05806840 | Wayne State University | N/A |
| Completed | Test of the Better Together Intervention NCT06594835 | Johns Hopkins Bloomberg School of Public Health | N/A |
| Completed | Peer Approaches to Substances in Early Psychosis Programs: A Pilot Study of a Peer-Led Intervention NCT04517279 | University of Texas at Austin | N/A |
| Active Not Recruiting | Maternal Brain Imaging in Opioid Use Disorder NCT06008990 | Indiana University | — |
| Recruiting | EMA for Predicting Treatment Outcomes in Patients With SUD NCT06470698 | University of Huelva | — |
| Completed | NOLA GEM: Feasibility and Acceptability of an MHealth Intervention for Violence-affected PLWH NCT05784714 | Tulane University | N/A |
| Recruiting | Project Khanya: Peer-Delivered Intervention to Improve HIV Medication Adherence and Substance Use in South Afr NCT05933226 | University of Maryland, College Park | N/A |
| Completed | NEXUS - Next Generation Health Through 2D & 3D Fetal UltraSound; Building Connections to Support Maternal-feta NCT05814575 | Virginia Commonwealth University | N/A |
| Unknown | tDCS and Impulsivity NCT05845164 | University of Arizona | N/A |
| Recruiting | A Regional Partnership to Improve Outcomes Through Fatherhood Engagement NCT05562557 | Montefiore Medical Center | N/A |
| Completed | Feasibility Study of a Web-based Program to Help Parents of Middle School Students Effectively Communicate Wit NCT05900115 | Innovation Research & Training | N/A |
| Recruiting | Family Spirit Strengths NCT05836090 | Johns Hopkins Bloomberg School of Public Health | N/A |
| Recruiting | A Novel Intervention for Patients With Cancer NCT05643027 | Dana-Farber Cancer Institute | N/A |
| Active Not Recruiting | Using the Ending Self-Stigma Intervention to Reduce Internalized Stigma Among People Living With HIV Who Use S NCT05704764 | Friends Research Institute, Inc. | N/A |
| Recruiting | Enhancing Wellness Through Affirming Services and Education NCT05700474 | Duke University | N/A |
| Completed | Relation Between Substance Use and Pain, in Patients Suffering or Surviving From Cancer and Followed in France NCT05684939 | University Hospital, Clermont-Ferrand | — |
| Recruiting | CARS: Cannabis and Alcohol Reduction Study NCT05486234 | Medical University of South Carolina | N/A |
| Unknown | Feasibility of Peer-mentor Delivered Substance Use Brief Intervention for Adolescents in Kenya NCT05545904 | Moi University | N/A |
| Completed | Mental Health, Gender-Based Violence, and Stunting in Tanzania NCT06065293 | Colorado State University | — |
| Recruiting | SmartSteps: A Context-Aware, PrEP Adherence Intervention for Individuals With Substance Use Disorder NCT05378399 | Brigham and Women's Hospital | Phase 3 |
| Completed | Effectiveness of a Mindfulness Program on Emotion Regulation Among Youth Attending an Alternative School NCT05619458 | University of Lethbridge | N/A |
| Active Not Recruiting | Examining Feasibility and Acceptability of Telemedicine for Substance Use Disorder (SUD) NCT04768920 | University of Michigan | N/A |
| Active Not Recruiting | Harnessing Telemedicine to Improve Alcohol Use Disorder Outcomes in Primary Care Patients NCT05410561 | University of Michigan | N/A |
| Completed | Dual Use Approach Bias Training for Nicotine Addiction NCT05306158 | University of Houston | N/A |
| Active Not Recruiting | A Brief Intervention for Alcohol Users With Interpersonal Trauma NCT05414344 | Western Kentucky University | N/A |
| Completed | An Online Intervention Addressing Mental Health and Substance Use in University Students NCT05606601 | University of British Columbia | N/A |
| Terminated | The Impact of Opioid and Cannabis Exposure on Fetal Growth NCT05899101 | Dr. Laura Gaudet | — |
| Completed | Data-driven Identification for Substance Misuse NCT03833804 | University of Wisconsin, Madison | N/A |
| Terminated | Efficacy of a Multi-level School Intervention for LGBTQ Youth NCT05541406 | Washington University School of Medicine | N/A |
| Terminated | Journey of Transformation Curriculum for Native American Adolescents NCT05274217 | University of Washington | N/A |
| Withdrawn | Trauma-Focused Intervention With Women Experiencing Homelessness NCT05873517 | Rush University Medical Center | Phase 1 |
| Recruiting | Culturally Responsive Community Driven Substance Use Recovery for Black and Latinx Population NCT05260047 | Yale University | N/A |
| Completed | Tobacco, Alcohol, Prescription Drug, and Illicit Substance Use- Electronic Spanish Platform NCT05476588 | Baylor Research Institute | N/A |
| Completed | A Library-based Prevention Intervention for Adolescents Affected by Parental Drug Use NCT05033821 | Johns Hopkins Bloomberg School of Public Health | N/A |
| Recruiting | Pre-exposure Prophylaxis (PrEP) Adherence Intervention for Women with Substance Use Disorders NCT06158607 | The University of Texas Health Science Center, Houston | N/A |
| Active Not Recruiting | Developing a Telehealth Model to Improve Treatment Access for Rural Veterans With Substance Use Disorders NCT05348317 | VA Office of Research and Development | N/A |
| Completed | Community Reinforcement and Family Training for Early Psychosis (CRAFT-EP) and Substance Use: A Pilot Study NCT05380583 | Mclean Hospital | N/A |
| Completed | Couples Health CoOp Plus NCT05310773 | RTI International | N/A |
| Recruiting | Harm Reduction in HIV Primary Care for PLWH Who Use Drugs NCT05404750 | University of Pittsburgh | — |
| Completed | Addressing Risk Through Community Treatment for Infectious Disease and Opioid Use Disorder Now (ACTION) Among NCT05286879 | Yale University | N/A |
| Completed | The Use of Cognitive Mindfulness for Chemsex NCT05929040 | London Metropolitan University | N/A |
| Recruiting | Parent SMART (Substance Misuse in Adolescents in Residential Treatment) NCT05169385 | Brown University | N/A |
| Unknown | Effectiveness of the Social Competence Promotion Program for Young Adolescents for Substance Use Prevention in NCT04236947 | Universidad de los Andes, Chile | N/A |
| Unknown | mHealth Systems Navigation- Breaking Systems Barriers for Trans Women Living With HIV NCT05196009 | Public Health Foundation Enterprises, Inc. | N/A |
| Completed | Community Reinforcement Approach and Family Training for Substance Use in Early Psychosis Intervention NCT05300633 | Centre for Addiction and Mental Health | N/A |
| Terminated | Evaluating the Effectiveness of a Drug Education and Diversion Program for Middle and High School Students NCT05321563 | Massachusetts General Hospital | N/A |
| Recruiting | Health and Resilience Projects: Foundations NCT05253235 | University of Georgia | N/A |
| Completed | Impact of Mindfulness Training on Adolescent Well-Being and Behavior NCT05537961 | University of Utah | N/A |
| Unknown | Abuse Potential and Human Pharmacology of Methylone NCT05488171 | Germans Trias i Pujol Hospital | Phase 1 |
| Completed | Psychotherapy for Psychosis, Adverse Events, and Substance Misuse NCT04546178 | Nova Scotia Health Authority | N/A |
| Active Not Recruiting | Expanding the Potential of Couples HIV Testing: Adjunct Modules to Reduce Drug Use Among Vulnerable Male Coupl NCT05000866 | Hunter College of City University of New York | N/A |
| Completed | Technology-Based Prevention for Adolescents in Primary Care NCT03489434 | Georgia State University | N/A |
| Active Not Recruiting | Assessing the PrEP Care Cascade Among Black Men and Transwomen in the Southeastern US NCT04832477 | University of Connecticut | N/A |
| Recruiting | Encouraging Abstinence Behavior in a Drug Epidemic: Optimizing Dynamic Incentives NCT04927143 | Wake Forest University Health Sciences | N/A |
| Completed | Automating Peer Learning to Reduce Alcohol Use and Related Deviant Behavior in Secondary School NCT04478240 | Oregon Research Behavioral Intervention Strategies, Inc. | N/A |
| Unknown | Unplugged, a Drug Use Prevention Program: Adaptation and Evaluation of Effectiveness Among Students in Chile NCT04236999 | Universidad de los Andes, Chile | N/A |
| Recruiting | MPFC Theta Burst Stimulation as a Treatment Tool for Alcohol Use Disorder: Effects on Drinking and Incentive S NCT04998916 | Medical University of South Carolina | N/A |
| Unknown | Validation of the Dutch Translation of the Tobacco, Alcohol, Prescription Medication and Other Substances (TAP NCT05273021 | Birgit Seelen-de Lang | — |
| Completed | Feasibility and Acceptability of a Substance Use Screening and Brief Intervention for Youth Living With HIV in NCT04998045 | Moi University | N/A |
| Completed | Telehealth-Clinical Advocacy Project NCT04911426 | Texas Christian University | N/A |
| Completed | Understanding and Reducing HIV Risk Behavior and Substance Use Among Self-identified Bisexual Adolescent Men NCT03409328 | Rosalind Franklin University of Medicine and Science | N/A |
| Unknown | A Scaleable Video Coaching Intervention for Opioid-using Mothers NCT04749771 | University of Oregon | N/A |
| Active Not Recruiting | Using Re-inforcement Learning to Automatically Adapt a Remote Therapy Intervention (RTI) for Reducing Adolesce NCT04850274 | University of Michigan | N/A |
| Completed | Effects of a Peer-led Educational Intervention Based on Theory of Planned Behavior on Substance Use Intentions NCT04863625 | Wollo University | N/A |
| Completed | Leveraging Social Networks to Increase COVID-19 Testing Uptake NCT04873401 | New York State Psychiatric Institute | N/A |
| Completed | Remotely Delivered Programs Targeting COVID-19 Stress-Related Depression and Substance Use NCT04595084 | Cambridge Health Alliance | N/A |
| Completed | Leveraging Evidence to Activate Parents NCT04779229 | Oregon Social Learning Center | N/A |
| Enrolling By Invitation | Tobacco-Concurrent Addictions in At-Risk Youth in Ottawa NCT04812613 | Ottawa Hospital Research Institute | — |
| Completed | EMA of Substance Use in Homeless Youth NCT04884087 | Nationwide Children's Hospital | N/A |
| Completed | Siyakhana Peer: Evaluating a Peer Recovery Coach Model to Reduce Substance Use Stigma in South African HIV Car NCT05907174 | University of Maryland, College Park | N/A |
| Completed | iSTART: A Campus & Community Initiative for Services in Tec-health NCT05362357 | California State University, Northridge | N/A |
| Completed | Preventing Opioid Use Among Justice-involved Youth as They Transition to Adulthood Leveraging Safe Adults (LeS NCT04678960 | Texas Christian University | N/A |
| Completed | A Social Network AOD Intervention for Homeless Youth Transitioning to Housing NCT04637815 | RAND | Phase 1 |
| Completed | Researching Resiliency in Stressful Experiences (RISE) Program for Men Leaving Incarceration NCT04785677 | Florida State University | N/A |
| Unknown | Online System for Primary Care to Prevent and Address Teen Substance Use NCT04689997 | Total Child Health, Inc. | N/A |
| Completed | Delivering Contingency Management in Outpatient Addiction Treatment NCT04544124 | University of Calgary | N/A |
| Active Not Recruiting | The Substance Abuse Treatment to HIV Care II (SAT2HIV-II) Project NCT04687917 | Ohio State University | N/A |
| Recruiting | ANCHORS Alcohol & Sexual Health Study: UH3 Project NCT04331704 | University of Florida | Phase 4 |
| Completed | Pilot Randomized Controlled Trial (RCT): Remote SBIRT Vs. In-Person SBIRT NCT04630249 | Medical University of South Carolina | N/A |
| Completed | Home Visitation Enhancing Linkages Project NCT03750487 | The National Center on Addiction and Substance Abuse at Columbia University | N/A |
| Completed | Feasibility and Efficacy of a Brief Mindfulness-Based Intervention SMOKING INTERVENTION VIA THE INTERNET NCT04572126 | Wayne State University | N/A |
| Completed | UTECH: Machine Learning for HIV Prevention Among Substance Using GBMSM NCT04710901 | University of California, Los Angeles | N/A |
| Completed | Randomized Trial of a Data-driven Technical Assistance System for Drug Prevention Coalitions NCT04592120 | The University of Texas Health Science Center, Houston | N/A |
| Completed | Peer-Delivered Behavioral Activation for Methadone Adherence - Pilot Phase NCT04248933 | University of Maryland, College Park | N/A |
| Completed | Mindfulness-based Intervention to Address PTSD in Trauma-exposed, Homeless Women NCT04605198 | University of California, Los Angeles | N/A |
| Completed | Families With Substance Use and Psychosis: A Pilot Study NCT04284813 | Mclean Hospital | N/A |
| Completed | Project Uplift: Substance Use and Mental Health Treatment for Young Sexual and Gender Minorities NCT04546061 | Duke University | N/A |
| Completed | KickStart30: A 30-Day Nursing Wellness Initiative NCT04459728 | University of Texas at Austin | N/A |
| Completed | Pilot Test of a Cultural Intervention to Enhance Alaska Native Students' Behavioral Health NCT04561544 | University of Alaska Anchorage | N/A |
| Terminated | Emergency Department Initiated Extended-Release Naltrexone and Case Management for the Treatment of Alcohol Us NCT04094584 | University of California, San Francisco | Phase 4 |
| Completed | Adolescent SCreening To Help Eliminate Misuse NCT04200339 | Boston Children's Hospital | — |
| Completed | A Substance Use Adaptation of Fathering Through Change NCT04532619 | University of Oregon | N/A |
| Completed | Prevention of OUD: The HOME Project (Housing, Opportunities, Motivation and Engagement) NCT04135703 | Ohio State University | N/A |
| Enrolling By Invitation | Alliances to Disseminate Addiction Prevention and Treatment (ADAPT) NCT04499079 | Indiana University | N/A |
| Completed | Project IntERact Study NCT03940716 | University of Michigan | N/A |
| Unknown | Evaluation of Thiwáhe Gluwáš'Akapi Substance Use Prevention Program NCT04222556 | University of Colorado, Denver | N/A |
| Unknown | Unidos Against ATOD Use Intervention Trial NCT03642106 | Oklahoma State University | N/A |
| Completed | Advancing Understanding of Transportation Options NCT04141891 | University of Colorado, Denver | N/A |
| Completed | Kentucky Communities and Researchers Engaging to Halt the Opioid Epidemic (CARE2HOPE) NCT04134767 | April M Young | N/A |
| Completed | Change in Cognitive Function in Stimulant Users NCT04061941 | The University of Hong Kong | — |
| Completed | Stigma, Risk Behaviors and Health Care Among HIV-infected Russian People Who Inject Drugs NCT03695393 | Boston Medical Center | N/A |
| Terminated | Attention Training on Smartphones NCT04097340 | University of Florida | N/A |
| Unknown | Using Values to Enhance Inmates' Response to Substance Use and HIV Risk Feedback NCT03501732 | George Mason University | N/A |
| Completed | Adaptive Interventions for Prevention/Intervention for Youth Substance Abuse NCT03928756 | University of Michigan | N/A |
| Completed | Regional Partnership for Pregnant Women at Risk of Substance Misuse and Their Newborns NCT03735212 | Montefiore Medical Center | N/A |
| Completed | Telling Our Daughters Our Story NCT06276595 | Johns Hopkins Bloomberg School of Public Health | N/A |
| Completed | Southwest Hub for American Indian Youth Suicide Prevention Research NCT03543865 | Johns Hopkins Bloomberg School of Public Health | N/A |
| Completed | Ambulance Calls for Substance Use and Alcohol in a Pandemic (ASAP) NCT04474444 | University of Lincoln | — |
| Completed | Mindfulness for at Risk Youth: Understanding Substance Use and Important Mechanisms of Change NCT04160754 | University of Southern California | N/A |
| Completed | Acceptability and Feasibility Study of the Program "Yo Se Lo Que Quiero" (Unplugged) NCT04566627 | Universidad de los Andes, Chile | N/A |
| Completed | Trauma Informed Prevention for Substance Use and Risky Sex NCT03710720 | Medical University of South Carolina | N/A |
| Withdrawn | Can The Bridge Transition Opiate Use Disorder Patients in Stable Recovery From Buprenorphine to Naltrexone NCT03762798 | The Cleveland Clinic | N/A |
| Completed | Intervention for Substance Use and Sexual Risk Behavior in Homeless Youth NCT03735784 | RAND | N/A |
| Unknown | IPS/Peer Support Intervention in the DTES NCT03748004 | University of British Columbia | N/A |
| Completed | Nexus of Risk: Sexual Assault, Alcohol Use, and Risky Sex Among College Women NCT05892692 | University of New Mexico | N/A |
| Unknown | Mobile Support to Improve Recovery and Treatment Court Outcomes NCT03668444 | Live Inspired, LLC | N/A |
| Completed | Young People's Health Assessment as Treatment and Health Guide NCT03817255 | University of Geneva, Switzerland | N/A |
| Withdrawn | Peer-to-peer Tobacco and ENDS Prevention NCT03491865 | Real Prevention, LLC | N/A |
| Completed | Youth to Text or Telehealth for Engagement in HIV Care NCT03681145 | University of California, San Francisco | N/A |
| Completed | Interactive Technology for Media Literacy Drug Prevention in Community Groups NCT03157700 | Real Prevention, LLC | N/A |
| Completed | Evaluation of Universal Prevention Curriculum for Schools in Peru NCT04699526 | HBSA | N/A |
| Completed | Improving HIV/Tuberculosis Outcomes in Irkutsk NCT03819374 | University of Virginia | — |
| Completed | Long-term Follow-up Study of Substance Abuse Screening and Intervention in Multi Primary Care Centers NCT03452241 | Shanghai Mental Health Center | N/A |
| Completed | Feasibility of SBIRT-PN NCT03057119 | Florida State University | N/A |
| Completed | Brief Intervention for Justice-Involved Substance Users NCT03308877 | University of Rochester | N/A |
| Completed | Strategies: Motivational Interviewing/Psychoeducation NCT03458299 | Pacific Institute for Research and Evaluation | N/A |
| Completed | Health and Justice: A Continuum of Care for HIV and SU for Justice-Involved Young Adults (PHASE 2) NCT03369249 | New York State Psychiatric Institute | N/A |
| Active Not Recruiting | Supportive Release Center Study NCT03616990 | University of Chicago | N/A |
| Completed | Developing SUPPORT, a Community-Driven, Recovery-Oriented System of Care NCT03132753 | Indiana University | N/A |
| Completed | Enhancing Permanency in Children and Families NCT04700696 | Ohio State University | N/A |
| Completed | Mobile Application to Improve Care Coordination Among HIV Clinic and Substance Use Treatment Providers NCT02906215 | University of Texas at Austin | N/A |
| Completed | SARA - Substance Abuse Research Assistant NCT03255317 | University of Michigan | N/A |
| Completed | Collaborative Care for Children's Mental Health Problems NCT03144739 | Johns Hopkins University | N/A |
| Completed | Utilizing Traditional Practices NCT03164577 | University of California, Los Angeles | N/A |
| Unknown | An Evidence-based Approach for Bullying Prevention NCT03205059 | National Health Promotion Associates, Inc. | N/A |
| Completed | Engaging Seronegative Youth to Optimize HIV Prevention Continuum NCT03134833 | University of California, Los Angeles | N/A |
| Completed | Optimizing HIV Counseling and Testing and Referral Through an Adaptive Drug Use Intervention NCT02945436 | University of Michigan | N/A |
| Completed | Trial of a Novel Brief Intervention on Health Behaviors for Youth With Chronic Medical Conditions NCT02803567 | Boston Children's Hospital | N/A |
| Completed | Adolescents With Substance Use Disorders Transitioníng From Residential Treatment to the Community NCT03592186 | Brown University | N/A |
| Completed | Adherence Through Home Education and Nursing Assessment, Indonesia NCT03397576 | University of Illinois at Chicago | N/A |
| Completed | Prevention of Substance Use in At-Risk Students: A Family-Centered Web Program NCT03060291 | University of Oregon | N/A |
| Completed | American Indian and Alaska Native Men Who Have Sex With Men HIV & Substance Abuse Research NCT03049904 | University of Washington | N/A |
| Completed | Effects of Core Stabilization Exercises on Pulmonary Functions, Respiratory Muscle Strength and Functional Cap NCT03461614 | Istanbul University | N/A |
| Unknown | Substance Use Screening Among Drug User NCT02951858 | Shanghai Mental Health Center | N/A |
| Completed | A Family-Centered Ojibwe Substance Abuse Prevention NCT02700035 | University of Nebraska Lincoln | N/A |
| Completed | Family Engagement, Cross-System Linkage to Substance Use Treatment for Juvenile Probationers -- Phase 3 NCT03048552 | New York State Psychiatric Institute | N/A |
| Completed | Specialty Mental Health Probation in North Carolina NCT02990026 | University of North Carolina, Chapel Hill | N/A |
| Completed | Employing eSBI in HIV Testing for At-risk Youth NCT02703116 | Ann & Robert H Lurie Children's Hospital of Chicago | N/A |
| Completed | Examining Community-based Effectiveness of a Substance Use and HIV Risk Reduction Intervention for Young Men o NCT03488914 | Hunter College of City University of New York | N/A |
| Unknown | Healthy Marriage and Responsible Fatherhood Grant Program With Phoenix House of New York NCT03640546 | Phoenix House Foundation, Inc. | — |
| Completed | Evaluation of a Brief Surf the Urge Intervention NCT02771886 | Kimberly N Schubert | N/A |
| Unknown | Adherence Intervention for HIV-infected Drug Users NCT02907697 | University of Texas at Austin | N/A |
| Completed | Assessing Long-term CTN 0049 Outcomes, HCV Prevalence and Progression Along the HCV Care Continuum Among HIV/H NCT02641158 | Columbia University | N/A |
| Completed | 'Keepin' It REAL in Mexico: An Adaptation and Multisite RCT Implementation of a Substance Abuse Prevention Cur NCT03233386 | Arizona State University | — |
| Unknown | Preventing Prescription Drug Abuse in Middle School Students NCT03129334 | National Health Promotion Associates, Inc. | N/A |
| Completed | Safety Awareness For Empowerment (SAFE): An RCT With Young People Experiencing Homelessness NCT04183400 | University of Denver | N/A |
| Completed | Substance Abuse Treatment to HIV Care (SAT2HIV): The Motivational Interviewing-based Brief Intervention Experi NCT02495402 | RTI International | N/A |
| Completed | BEing Safe in Treatment NCT03575585 | University of Washington | Phase 2 |
| Active Not Recruiting | Fostering Healthy Futures for Teens: An RCT NCT03707366 | University of Denver | N/A |
| Unknown | Primary Prevention of Sexual Violence Among College Students NCT03037866 | National Health Promotion Associates, Inc. | N/A |
| Completed | Evaluation of EBT With Young, Substance Abusing Homeless Mothers NCT02577666 | Ohio State University | N/A |
| Completed | Substance Abuse Treatment to HIV Care (SAT2HIV): The Implementation & Sustainment Facilitation Experiment NCT03120598 | RTI International | N/A |
| Unknown | Computer Adaptation of Screening, Brief MET Intervention to Reduce Teen Drinking NCT01881841 | Boston Children's Hospital | N/A |
| Unknown | Effects of Physical Activity in Psychosis NCT02205684 | Sykehuset i Vestfold HF | N/A |
| Terminated | Study on the Impact of Patient Navigators on the Health Education and Quality of Life in Formerly Incarcerated NCT02259634 | St. Luke's-Roosevelt Hospital Center | N/A |
| Completed | Substance Use Screening and Prevention for Adolescents in Pediatric Primary Care NCT03074877 | RTI International | N/A |
| Completed | Stigma Intervention Among Primary Health Workers in Toronto NCT03043417 | Centre for Addiction and Mental Health | N/A |
| Completed | Intertribal Talking Circle for the Prevention of Substance Abuse in Native Youth NCT03086434 | Florida State University | N/A |
| Completed | Evaluation of an Entrepreneurship Program for American-Indian Youth NCT02157493 | Johns Hopkins Bloomberg School of Public Health | N/A |
| Completed | Promoting Sleep to Prevent Substance Use in Adolescence NCT02463188 | University of California, Berkeley | N/A |
| Active Not Recruiting | Neurocognitive Predictors of Health Risk Behaviors NCT06941181 | Virginia Polytechnic Institute and State University | N/A |
| Completed | CBT for Spanish Speakers NCT02043210 | Yale University | N/A |
| Completed | Substance Use and Sexual Risk Reduction Intervention for Homeless Youth NCT02188797 | RAND | N/A |
| Completed | The ProGirls Study NCT02112201 | Oregon Research Institute | N/A |
| Completed | Culturally Grounded Early Substance Use Prevention for American Indian Families NCT02383225 | University of Colorado, Denver | N/A |
| Terminated | Brief Motivational Enhancement Therapy for Concurrent Disorders NCT01924039 | Centre for Addiction and Mental Health | N/A |
| Completed | Multicomponent Intervention to Reduce Sexual Risk and Substance Use NCT01880489 | Hunter College of City University of New York | N/A |
| Completed | Concurrent Treatment of Substance Abuse and Child Maltreatment NCT02774525 | University of South Carolina | N/A |
| Completed | HIV Prevention for HIV-Negative Men Via Reduction of Social Anxiety NCT02045225 | Toronto Metropolitan University | Phase 1 |
| Completed | Creatine as a Treatment Option for Depression in Methamphetamine Using Females NCT01514630 | Perry Renshaw | Phase 4 |
| Completed | The Effect of Energy Drink Consumption on Alcohol-Substance Use and It's Relationship With Impulsivity In Univ NCT02593617 | Mustafakemalpasa State Hospital | N/A |
| Unknown | Alcohol Use and Relationships - III NCT01753986 | The University of Tennessee, Knoxville | Phase 2 |
| Completed | Treating Chronic Pain in Buprenorphine Patients in Primary Care Settings NCT01752998 | Butler Hospital | N/A |
| Completed | HOPE Demonstration Field Experiment Multisite Evaluation NCT01670708 | RTI International | N/A |
| Completed | Motivational Interviewing Integrated With Social Network Counseling for Teens NCT01922947 | Virginia Commonwealth University | N/A |
| Withdrawn | Integration of (iSBIRT) for Teen Drug Use Into a Pediatric Network NCT01454206 | Boston Children's Hospital | Phase 2 / Phase 3 |
| Completed | Psychological First Aid for Victims of Crime NCT01934348 | Medical University of South Carolina | Phase 1 / Phase 2 |
| Completed | Screening, Brief Intervention, and Referral to Treatment for Offenders NCT01683643 | University of California, Los Angeles | N/A |
| Terminated | Open-Label Creatine Study for Female Meth Users NCT02189915 | Perry Renshaw | N/A |
| Completed | An Innovative HIV Prevention Intervention Using Social Networking Technology NCT01381653 | Hunter College of City University of New York | N/A |
| Terminated | Brief Intervention and Referral to Treatment With Substance Use Disorders in the Emergency Room Setting NCT01661517 | University of Alabama at Birmingham | EARLY_Phase 1 |
| Terminated | Routine Clinical Screening for Substance Use Disorders in the Emergency Room Setting NCT01661465 | University of Alabama at Birmingham | — |
| Completed | Individual and Family Motivational Interviews for Substance Using Truant Teens NCT01170026 | Brown University | N/A |
| Completed | Familias Unidas: Preventing Substance Abuse in Hispanic Youth NCT01038206 | University of Miami | Phase 2 / Phase 3 |
| Completed | Impact of a Computer-Assisted SBIRT Program in an HIV Care Setting NCT01300806 | University of California, San Francisco | — |
| Completed | Familias Unidas: Preventing Drug Abuse and HIV in Hispanic First Offenders NCT01257022 | University of Miami | Phase 2 |
| Completed | The Impact of Psychopathic Traits on the Efficacy of a Substance Use Intervention NCT01532934 | University of Rochester | Phase 2 |
| Completed | Preventing Adolescents From Entering the Juvenile Justice System NCT02147743 | University of Miami | N/A |
| Completed | Reducing HIV: Safer Sex Skill Building in Pregnant Drug Abusing Women NCT00619320 | Virginia Commonwealth University | Phase 2 / Phase 3 |
| Completed | Reinforcing Therapist Performance NCT01016704 | Chestnut Health Systems | N/A |
| Completed | Targeting HIV Risk Behaviors in Juvenile Drug Court-Involved Youth NCT01511380 | Medical University of South Carolina | Phase 2 |
| Completed | Behavioral Depression Treatment for African American HIV-infected Substance Users NCT01351454 | University of North Carolina, Chapel Hill | N/A |
| Completed | Age-17 Follow-up of Home Visiting Intervention NCT00708695 | University of Colorado, Denver | — |
| Completed | Adaptation Processes in School-Based Substance Abuse Programs NCT01755533 | Penn State University | N/A |
| Completed | Effectiveness Study of a Swedish Youth Mentoring Program NCT01138982 | Karolinska Institutet | N/A |
| Unknown | Brief Intervention to Reduce Drinking and Intimate Partner Violence in Women NCT00539812 | The University of Tennessee, Knoxville | Phase 2 |
| Completed | Group CBT for Depression and AOD Disorders NCT01154309 | RAND | Phase 1 |
| Completed | Building Recovery By Improving Goals, Habits, and Thoughts NCT01191788 | RAND | N/A |
| Completed | 15 Year Follow-up of New Beginnings Program for Divorced Families NCT01407120 | Arizona State University | Phase 2 / Phase 3 |
| Completed | Risk Reduction Intervention for Vulnerable Young Adult Males NCT01118416 | Hunter College of City University of New York | N/A |
| Completed | Martial Arts as Early Intervention for Teen Drug Abuse NCT00956527 | University of Colorado, Denver | N/A |
| Completed | Juvenile Detention to Community Life NCT01910324 | University of Miami | N/A |
| Completed | A Family Intervention for Adolescent Problem Behavior (AKA Project Alliance 2) NCT01490307 | University of Oregon | N/A |
| Completed | Trial of Automated Risk Appraisal for Adolescents NCT00505440 | Nationwide Children's Hospital | N/A |
| Completed | Mothers Living With HIV and Their Adolescent Children NCT00988390 | University of California, Los Angeles | N/A |
| Completed | Drug Abuse Prevention Among Girls Through a Mother-Daughter Intervention NCT01236248 | Columbia University | N/A |
| Completed | Behavioral Intervention for Minority Adolescent Women NCT01387646 | The University of Texas Health Science Center at San Antonio | Phase 2 |
| Completed | Randomized Trial of the Positive Action Program in Chicago Schools and Extension to Grade 8 NCT01025674 | Oregon State University | N/A |
| Completed | Support To Reunite Involve and Value Each Other NCT00996541 | University of California, Los Angeles | N/A |
| Completed | Family-Based Juvenile Drug Court Services NCT01668303 | University of Miami | N/A |
| Completed | Brief Intervention in At-Risk First-time Mothers NCT00230009 | Wayne State University | Phase 1 / Phase 2 |
| Completed | Early Family-Centered Prevention of Drug Use Risk (Aka Early Steps) NCT01098695 | University of Oregon | N/A |
| Completed | Randomized Trial of the Positive Action Program in Hawaii Schools NCT00328445 | National Institute on Drug Abuse (NIDA) | N/A |
| Completed | Family-based and Adolescent Residential Drug Treatment NCT01737632 | University of Miami | N/A |
| Completed | Exploring the Comorbidity Between Mental Disorders and General Medical Conditions NCT03847753 | University of Aarhus | — |