NCT05306158

Dual Use Approach Bias Training for Nicotine Addiction

Approach Bias Retraining for Nicotine Addiction Among Dual Combustible and Electronic Cigarette Users

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 107 (actual)
• Sponsor: University of Houston · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The present project will evaluate the initial efficacy of approach bias retraining among dual combustible cigarette (CC) and electronic cigarette (ECIG) users. The study employs a randomized controlled design to follow 90 experienced dual CC/ECIG users motivated to quit nicotine as they engage in a self-guided quit attempt following approach bias retraining.

Detailed description

The study employs a randomized controlled design to follow 90 experienced dual CC/ECIG users motivated to quit nicotine as they engage in a self-guided quit attempt following approach bias retraining. Participants will be randomized to one of three approach bias retraining conditions: (1) CC+ECIG; (2) CC only; or (3) sham (control). Participants will complete a phone pre-screener, baseline (week 1 of study participation), 4 approach bias retraining sessions in laboratory (with quit day scheduled for the 4th session; weeks 2-5 of study participation), and follow-up assessments at 4- and 6-weeks post-intervention (i.e., weeks 9 and 11 of study participation, respectfully). Participants also will complete ecological momentary assessments (EMA) of CC smoking, ECIG use, and CC and ECIG urges/cravings for 14 days post-intervention (i.e., weeks 5-7 of study participation) on Internet capable smartphones. The only time data will be collected is when participants complete EMA assessments or follow up surveys using the REDCap app on the smartphone.

Conditions

• Tobacco Smoking
• Electronic Cigarette Use
• Substance Use

Interventions

Type	Name	Description
OTHER	CC+ECIG Condition	Participants will push CC- and ECIG-related pictures.
OTHER	CC Condition	Participants will push CC-related images and push and pull ECIG-related pictures equally often.
OTHER	Sham Condition	Participants will pull and push CC- and ECIG-related pictures equally often.

Timeline

• Start date: 2022-10-03
• Primary completion: 2024-09-30
• Completion: 2024-11-30
• First posted: 2022-03-31
• Last updated: 2025-03-27

Locations

1 site across 1 country: United States