NCT07512869

Host Led Harm Reduction Approach Among Men Who Have Sex With Men Who Engaged in Chemsex in Bangkok, Thailand: A Pre-Implementation Study

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 76 (estimated)
• Sponsor: Institute of HIV Research and Innovation Foundation, Thailand · Academic / Other
• Sex: Male
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study evaluates the pre-implementation phase of a host-led harm reduction model for men who have sex with men (MSM) engaging in chemsex in Bangkok, Thailand, focusing on understanding harms, contexts, and needs to develop a tailored intervention.

Detailed description

HAMMOCK is a cross-sectional mixed-methods study designed to explore chemsex practices among MSM, including both hosts and guests, as well as key stakeholders such as CSOs, hospital staff, and police. The study aims to: * Explore substance-related, sexual health, mental health, and socio-legal harms * Understand the context and dynamics of private chemsex parties * Co-develop a novel host-led harm reduction model * Identify barriers and facilitators to implementation The study includes both quantitative (self-administered questionnaires) and qualitative (in-depth interviews) components and follows a two-phase approach: exploration and preparation phases under the EPIS framework.

Conditions

• HIV Prevention
• Substance Use
• Mental Health
• Sexually Transmitted Infections (STIs)

Interventions

Type	Name	Description
BEHAVIORAL	Self-administered questionnaire assessment	Participants (chemsex party hosts and guests) will complete structured self-administered questionnaires to assess: * Substance use patterns and related harms * Sexual health risks (e.g., condom use, HIV/STI testing, PrEP/ART adherence) * Mental health status using validated tools: * Patient Health Questionnaire-9 (PHQ-9) * Generalized Anxiety Disorder-7 (GAD-7) * Socio-legal harms including stigma and discrimination
BEHAVIORAL	Semi-structured in-depth interviews (IDIs)	All stakeholders will participate in semi-structured in-depth interviews: * Exploration phase: guided by EPIS framework * Preparation phase: guided by * Theoretical Domains Framework (TDF) (hosts \& guests) * Consolidated Framework for Implementation Research (CFIR) (organizational stakeholders) The interviews aim to: * Identify harms associated with chemsex * Explore current practices and contexts * Identify barriers and facilitators * Inform development and refinement of a harm reduction model
BEHAVIORAL	Development and refinement of harm reduction model	A novel four-pronged harm reduction model will be developed and refined based on quantitative and qualitative findings. Domains include: * Substance use harm reduction * Sexual health harm reduction * Mental health harm reduction * Socio-legal harm reduction

Timeline

• Start date: 2025-02-17
• Primary completion: 2027-02-17
• Completion: 2028-12-30
• First posted: 2026-04-06
• Last updated: 2026-04-06

Locations

1 site across 1 country: Thailand