| Not Yet Recruiting | Prevalence and Molecular Identification of Human Schistosomiasis NCT07482215 | Assiut University | — |
| Recruiting | Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective NCT07358910 | Institut Pasteur du Cambodge | — |
| Not Yet Recruiting | Female Genital Schistosomiasis in Migrant Women: A Pilot Study NCT06828536 | Assistance Publique - Hôpitaux de Paris | N/A |
| Recruiting | Introduction of Arpraziquantel Treatment for Schistosomiasis Control in Preschool-aged Children in Endemic Are NCT06698510 | Peter Steinmann | — |
| Unknown | Sm-p80 Schistosomiasis Challenge Study NCT05999825 | Leiden University Medical Center | Phase 2 |
| Recruiting | Assessment of Infection Activity in Travelers and Migrants Diagnosed With Chronic Schistosomiasis NCT06873308 | IRCCS Sacro Cuore Don Calabria di Negrar | N/A |
| Unknown | Effectiveness and Cost-effectiveness of Integrated Model for Malaria and Helminth Control NCT06182176 | London School of Hygiene and Tropical Medicine | N/A |
| Active Not Recruiting | Evaluation of a Comprehensive School Health Programme in Zambia NCT06560853 | London School of Economics and Political Science | N/A |
| Completed | Health Education Model Led by Community Health Volunteers. NCT06312462 | Pemba Ministry of Health Zanzibar | N/A |
| Completed | Delivering a Multi-disease Screening Tool to Migrant Populations NCT05868005 | Barcelona Institute for Global Health | N/A |
| Completed | A Study to Evaluate the Safety, Tolerability, and Immunogenicity of the Sm-p80 + GLA-SE (SchistoShield®) Candi NCT05762393 | International Vaccine Institute | Phase 1 |
| Unknown | Feasibility and Safety of Combining Anti-malarial With Deworming Drugs in African Children NCT05354258 | London School of Hygiene and Tropical Medicine | N/A |
| Completed | Safety, Tolerability, and Immunogenicity Study of Sm-p80 + GLA-SE (SchistoShield(R)) Vaccine in Healthy Adults NCT05292391 | National Institute of Allergy and Infectious Diseases (NIAID) | Phase 1 |
| Completed | Retrospective Study of Clinical Practice and Management of Imported Schistosomiasis in France NCT04810741 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Repeated Controlled Human Schistosoma Mansoni Infection NCT05085470 | Leiden University Medical Center | N/A |
| Unknown | Praziquantel in Children Under Age 4 NCT03640377 | Rhode Island Hospital | Phase 2 |
| Unknown | Selexipag for the Treatment of Schistosomiasis-Associated Pulmonary Arterial Hypertension NCT04589390 | University of Sao Paulo General Hospital | Phase 2 |
| Completed | Single-sex Female Controlled Human Schistosomiasis Mansoni Infection NCT04269915 | Leiden University Medical Center | N/A |
| Unknown | Monitoring Schistosome Hybrids Under Under Praziquantel Pressure NCT04635553 | Institut de Recherche pour le Developpement | — |
| Completed | Sm-TSP-2 Schistosomiasis Vaccine in Healthy Ugandan Adults NCT03910972 | Baylor College of Medicine | Phase 1 / Phase 2 |
| Completed | Treatment of Female Genital Schistosomiasis (FGS) With Praziquantel: A Proof-of-Concept Study NCT04115072 | Regionshospital Nordjylland | Phase 2 / Phase 3 |
| Completed | L-PZQ ODT in Schistosoma Infected Children NCT03845140 | Merck KGaA, Darmstadt, Germany | Phase 3 |
| Completed | Anti-Schistosomiasis Vaccine: Sm14 Phase 2b-Sn in School Children NCT03799510 | Oswaldo Cruz Foundation | Phase 2 |
| Completed | Repeated Doses of Praziquantel in Schistosomiasis Treatment (RePST) NCT02868385 | Leiden University Medical Center | Phase 3 |
| Completed | A Phase Ib Study of the Safety, Reactogenicity, and Immunogenicity of Sm-TSP-2/Alhydrogel)(R) With or Without NCT03110757 | National Institute of Allergy and Infectious Diseases (NIAID) | Phase 1 |
| Terminated | Seropositivity and Adverse Birth Events in Migrants From Bilharzia-endemic Areas NCT03158298 | Jena University Hospital | — |
| Unknown | Schistosomiasis in Senegal NCT03187366 | University of Notre Dame | N/A |
| Completed | Study of Safety and Immune Response of the Sm14 Vaccine in Adults of Endemic Regions NCT03041766 | Oswaldo Cruz Foundation | Phase 2 |
| Completed | Single-sex Controlled Human Schistosomiasis Infection: Safety and Dose Finding NCT02755324 | Leiden University | N/A |
| Completed | An Open Label Dose Finding Safety and Efficacy in Children and Infants Infected With Schistosomiasis (S.Manson NCT02806232 | Merck KGaA, Darmstadt, Germany | Phase 2 |
| Withdrawn | Effect of Concomitant Mansonella Perstans Microfilaremia on Immune Responses Following Single Dose Praziquante NCT02734186 | National Institute of Allergy and Infectious Diseases (NIAID) | Phase 4 |
| Completed | Childhood Schistosomiasis: a Novel Strategy Extending the Benefits/Reach of Antihelminthic Treatment NCT02495909 | University of Edinburgh | — |
| Completed | A Phase I Study of the Safety, Reactogenicity, and Immunogenicity of Sm-TSP-2/Alhydrogel® With or Without GLA- NCT02337855 | National Institute of Allergy and Infectious Diseases (NIAID) | Phase 1 |
| Completed | Detection of Schistosomiasis CAA in Travellers After High-risk Water Contact NCT02194712 | Meta Roestenberg | — |
| Completed | Diagnosis of Neglected Tropical Diseases Among Patients With Persistent Digestive Disorders NCT02105714 | Swiss Tropical & Public Health Institute | — |
| Completed | Arachidonic Acid Treatment Against Schistosomiasis Infection in Children NCT02144389 | dsm-firmenich Switzerland AG | N/A |
| Unknown | Evaluation of Strategies for Improved Uptake of Preventive Treatment for Intestinal Schistosomiasis NCT01869465 | Makerere University | N/A |
| Completed | Health Benefits of Repeated Treatment in Pediatric Schistosomiasis NCT01424410 | University of Edinburgh | — |
| Completed | Praziquantel-Pharmacokinetic Study NCT01288872 | National Institute of Allergy and Infectious Diseases (NIAID) | Phase 1 |
| Completed | Schistosomiasis Effect on Response to Vaccines, Anaemia and Nutritional Status of Children of Northern Senegal NCT01553552 | Biomedical Research Center EPLS | — |
| Completed | Study to Evaluate the Safety of the Vaccine Prepared sm14 Against Schistosomiasis NCT01154049 | Oswaldo Cruz Foundation | Phase 1 |
| Completed | Prevalence of Chronic Kidney Disease (CKD) and Risk Factors in Sub-Saharan Africa NCT03458338 | University Hospital, Basel, Switzerland | — |
| Unknown | Artemisinin-based Combination Therapy-Intermittent Preventive Treatment (ACT-IPT) Trial Among Schoolchildren i NCT01459146 | Navrongo Health Research Centre, Ghana | Phase 4 |
| Completed | Correlating Protection Against Malaria With Serum Profiles Against Plasmodium Falciparum Antigen Repertoires NCT01214876 | Radboud University Medical Center | — |
| Unknown | Antioxidant Supplements in the Reversal of Schistosomal Peri-portal Fibrosis NCT01260012 | Addis Ababa University | N/A |
| Completed | Schistosoma Haematobium Infections and Praziquantel NCT01558336 | University of Khartoum | Phase 3 |
| Completed | S. Japonicum and Pregnancy Outcomes NCT00486863 | National Institute of Allergy and Infectious Diseases (NIAID) | Phase 2 |
| Completed | Schistosomiasis in Women of Reproductive Age in Burkina Faso: Implications for Control NCT00463632 | DBL -Institute for Health Research and Development | — |
| Completed | Women and Children as the Focus for Control of Schistosomiasis Infections in the Irrigations Area of Burkina F NCT00463528 | DBL -Institute for Health Research and Development | — |
| Completed | Schistosomiasis in Formal and Non-Formal Schools in Uganda: Implications for Control Programmes NCT00463593 | DBL -Institute for Health Research and Development | — |
| Completed | Using Community-Based Volunteers to Reach Non-Enrolled School Aged Children Through Community-Directed Treatme NCT00463931 | DBL -Institute for Health Research and Development | — |
| Completed | The Effect of Praziquantel Treatment on Schistosoma Mansoni Morbidity and re-Infection Along Lake Victoria, Ug NCT00215267 | DBL -Institute for Health Research and Development | N/A |
| Completed | Iron Supplementation in Schistosomiasis and Soil Transmitted Helminths Control Programmes in Zambia NCT00276224 | DBL -Institute for Health Research and Development | N/A |
| Completed | Clinical Trial of Bilhvax,a Vaccine Candidate Against Schistosomiasis NCT01512277 | University Hospital, Lille | Phase 1 |