Trials / Completed
CompletedNCT05085470
Repeated Controlled Human Schistosoma Mansoni Infection
Safety and Protective Efficacy of Repeated Controlled Human Schistosoma Mansoni Infection
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 24 (actual)
- Sponsor
- Leiden University Medical Center · Academic / Other
- Sex
- All
- Age
- 18 Years – 45 Years
- Healthy volunteers
- Accepted
Summary
A group of 24 healthy volunteers are challenged one or three times with 20 male Schistosoma mansoni cercariae to investigate whether this leads to protection and to identify potential correlates of protection
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | Schistosoma mansoni infection | 20 viable male Schistosoma mansoni cercariae of the Puerto Rican strain |
| BIOLOGICAL | Placebo mock infection | Placebo mock infection with water |
Timeline
- Start date
- 2021-10-29
- Primary completion
- 2023-01-11
- Completion
- 2023-01-11
- First posted
- 2021-10-20
- Last updated
- 2023-01-30
Locations
1 site across 1 country: Netherlands
Source: ClinicalTrials.gov record NCT05085470. Inclusion in this directory is not an endorsement.