NCT07482215

Prevalence and Molecular Identification of Human Schistosomiasis

Prevalence and Molecular Identification of Human Schistosomiasis With Assessment of Associated Epidemiological Risk Factors in Assiut Governorate, Egypt

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 359 (estimated)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: —

Summary

Schistosomiasis remains one of the most important parasitic diseases of public health concern, particularly in developing countries including Egypt. It is caused by a trematode worm (blood flukes) of the genus Schistosoma

Detailed description

Schistosomiasis has been diagnosed in Egypt since pharaonic times (3200 B.C.) by recovering Schistosome eggs and antigens in ancient mummies.In Egypt, Schistosoma mansoni and Schistosoma haematobium have historically been highly endemic, with widespread distribution along the Nile Delta and Valley.(4) Schistosoma haematobium is responsible for urogenital schistosomiasis, with hematuria as its primary manifestation, while Schistosoma mansoni, the prevalent species in Egypt, is causing intestinal schistosomiasis with liver-related sequelae

Conditions

• Schistosomiasis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Molecular phylogenetic and haplotype analysis	DNA Sequencing and cox1 Gene Analysis of Schistosoma Isolates

Timeline

• Start date: 2026-05-01
• Primary completion: 2027-08-01
• Completion: 2027-12-01
• First posted: 2026-03-19
• Last updated: 2026-03-19