| Recruiting | Surgical Procedure Efficiency Evaluation stuDy NCT07228091 | Alcon Research | — |
| Not Yet Recruiting | Animated Video Education for Retinal Surgery NCT07184255 | University of Toronto | N/A |
| Recruiting | Nicotinamide Riboside Oral Supplementation in Macula Off Retinal Detachment NCT06587945 | Center for Eye Research Australia | Phase 4 |
| Active Not Recruiting | Head Position Monitoring After Pars Planar Vitrectomy NCT06985030 | Seoul National University Hospital | — |
| Recruiting | Ursodeoxycholic Acid (UDCA) as a Neuroprotective Adjuvant Treatment to Rhegmatogenous Retinal Detachment Surge NCT06294847 | Hopital Foch | Phase 3 |
| Completed | Methotrexate in Retinal Detachment With Proliferative Vitreoretinopathy NCT07058337 | Benha University | N/A |
| Unknown | Clinical Characteristics and Surgical Outcomes of the Fellow Eye in Bilateral Retinal Detachments NCT06292572 | Central Hospital, Nancy, France | — |
| Terminated | Lamivudine and Plasma Markers of Inflammation in Retinal Detachment NCT06056596 | University of Wisconsin, Madison | EARLY_Phase 1 |
| Recruiting | Proteomic Biomarker Identification in AMD, Diabetic Retinopathy and Retinal Detachment NCT07500324 | Fondazione G.B. Bietti, IRCCS | N/A |
| Active Not Recruiting | Subjective Pain Scoring for Subtenonal Anesthesia During Vitrectomy NCT06830070 | Prim. Prof. Dr. Oliver Findl, MBA | — |
| Recruiting | REtinal Detachment Outcomes Study NCT05863312 | CHU de Quebec-Universite Laval | N/A |
| Suspended | Clinical Investigation of the Safety and Effectiveness of the ABV-1701 Ocular Endotamponade (OE) NCT05414747 | BioFirst Corporation | N/A |
| Completed | Zeiss RESIGHT Disposable Lenses Evaluation Study NCT05860985 | Universitaire Ziekenhuizen KU Leuven | N/A |
| Completed | Duration of Silicone Oil Tamponade on Foveal and Parafoveal Thickness in Rhegmatogenous Retinal Detachment NCT05817630 | Dar El Oyoun Hospital | — |
| Completed | Outcomes of Retinal Re-surgeries in Silicone Oil Filled Eyes NCT06583798 | Ahalia Foundation Eye Hospital | — |
| Completed | Correlation Between OCT and mFERG Findings With VA After Vitrectomy Surgery for Retinal Detachment NCT05993208 | New Valley University | — |
| Unknown | Visual Outcome of Vitrectomy After Refractive Surgery NCT05583253 | Benha University | N/A |
| Unknown | Retinal Oxygenation Estimation Trial With Mantis Photonics Hyperspectral Camera NCT05566626 | Mantis Photonics AB | N/A |
| Unknown | Air Versus Gas Tamponade in Primary Retinal Detachment NCT05561569 | Benha University | N/A |
| Unknown | Effect of Intraocular Tamponade on Visual Perception NCT05543018 | Benha University | N/A |
| Not Yet Recruiting | Internal Limiting Membrane Peeling in Retinal Detachment Surgery NCT05538156 | Central Hospital, Nancy, France | N/A |
| Active Not Recruiting | Impact of ILM Peeling in RRD/ I-Peel NCT04767555 | Berner Augenklinik | N/A |
| Recruiting | Spring Loaded Syringe for Active Silicon Oil Extraction NCT07363889 | Sohag University | N/A |
| Unknown | Evaluation of Vitrectomy With ILM Peeling in Myopic Macular Hole With Only Posterior Retinal Detachment NCT06194760 | Al-Azhar University | N/A |
| Unknown | High Resolution Optical Coherence Tomography NCT05130385 | Insel Gruppe AG, University Hospital Bern | — |
| Completed | Intravitreal Infliximab for Proliferative Vitreoretinopathy NCT04891991 | Cairo University | Phase 2 |
| Completed | Efficacy of 5-fluorouracil and Low Molecular Weight Heparin in High-risk Pediatric Retinal Detachment NCT06166914 | Alexandria University | N/A |
| Completed | Early VItrectomy in DENse Spontaneous Vitreous HEmorrhage NCT04676256 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Performance Comparison of the 25 Gauge 20,000cpm HYPERVIT Dual Blade vs. 10,000cpm ULTRAVIT Vitrectomy Cutter NCT05710458 | The University of Hong Kong | N/A |
| Unknown | Quantification of Silicone Oil Emulsification After Pars Plana Vitrectomy NCT04774146 | Ospedale Policlinico San Martino | — |
| Unknown | Pars Plana Vitrectomy With 25-gauge 20000 Cpm, Bevel-tip Cutter NCT04404296 | Peregrine Eye and Laser Institute | N/A |
| Unknown | Retinal Displacement Rates in Pneumatic Retinopexy Versus Pars Plana Vitrectomy For Primary Retinal Detachment NCT04158622 | Unity Health Toronto | N/A |
| Unknown | Multimodal Imaging in Vitreo-retinal Surgery and Macular Dystrophies NCT05747144 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Completed | Refractive Changes Following Vitrectomy NCT04712786 | Bursa Retina Eye Hospital | — |
| Completed | Efficacy of Exercise Program for Facedown Posture-related Pain After Retinal Surgery NCT04535622 | Samsung Medical Center | N/A |
| Unknown | Suprachoroidal Buckling for the Management of Rhegmatogenous Retinal Detachment NCT04518696 | Fang Wang | N/A |
| Completed | Computer Aided Diagnosis of Multiple Eye Fundus Diseases From Color Fundus Photograph NCT04723160 | Visionary Intelligence Ltd. | — |
| Terminated | Assessing the Efficacy and Safety of DEXTENZA in Pseudo Phakic Patients Undergoing Gas Bubble Repair and Laser NCT04464629 | Midwest Eye Institute | Phase 4 |
| Terminated | Amniotic Membrane Visio-AMTRIX in Recurrent Macular Hole NCT05191628 | TBF Genie Tissulaire | Phase 2 |
| Completed | Evolution of Aqueous Flare in Rhegmatogenous Retinal Detachments Treated With Gas or Silicone Oil Tamponade. NCT05053698 | Central Hospital, Nancy, France | — |
| Unknown | Oral Sedation in Vitreoretinal Surgery NCT04346095 | Rocky Vista University, LLC | Phase 4 |
| Completed | Using Triamcinolone Acetonide to Reduce Pain After Scleral Buckle Surgery NCT04701593 | Virginia Polytechnic Institute and State University | Phase 4 |
| Unknown | Bimodal and Coaxial High Resolution Ophtalmic Imaging NCT04620876 | Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts | N/A |
| Unknown | Effect of Type of Head Positioning on Retinal Displacement in Vitrectomy for Retinal Detachment NCT04035343 | Unity Health Toronto | N/A |
| Recruiting | High Resolution, High-speed Multimodal Ophthalmic Imaging NCT04129021 | Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts | N/A |
| Terminated | Peeling of the Internal Limiting Membrane During Primary Vitrectomy for Retinal Detachment Repair NCT07438210 | Vienna Institute for Research in Ocular Surgery | N/A |
| Unknown | Feasibility Study and Preliminary Application Study on Iris OCTA NCT03631108 | Shanghai Eye Disease Prevention and Treatment Center | — |
| Recruiting | Intraoperative OCT Guidance of Intraocular Surgery II NCT03713268 | Duke University | — |
| Completed | Silicone Oil Versus Gas in PDR Patients Undergoing Vitrectomy NCT03660384 | Rush Eye Associates | N/A |
| Completed | Retinal Displacement After Pneumatic Versus Vitrectomy for Retinal Detachment (ALIGN) NCT04089033 | Unity Health Toronto | — |
| Completed | Performance, Safety and Efficiency Comparison Between 10,000 and 5,000 Cuts Per Minute Vitrectomy Using a 25G NCT04859556 | The University of Hong Kong | N/A |
| Completed | Internal Limiting Membrane Flaps for Coexistent Macular Hole and Retinal Detachment NCT03618498 | Changhua Christian Hospital | N/A |
| Completed | Use of Ocular Point of Care Ultrasound in Diagnosing Retinal Detachment in the Emergency Department NCT03106025 | Loma Linda University | N/A |
| Unknown | Amniotic Membrane for Recurrent Macular Hole NCT03528122 | Minia University | N/A |
| Unknown | Preoperative Progression of Retinal Detachment NCT03655652 | Glostrup University Hospital, Copenhagen | — |
| Completed | Evaluation of Discomfort Associated With Scleral Depression During Retina Examinations NCT04115917 | New York City Health and Hospitals Corporation | N/A |
| Completed | A Study of Fluoroquinolones Exposure and Collagen-Related Serious Adverse Events NCT03479736 | Janssen Research & Development, LLC | — |
| Completed | Intravitreous CytokinE Level in pAtient With retiNal Detachment NCT03318588 | Central Hospital, Nancy, France | — |
| Completed | Double Retinal Tamponade for Retinal Detachment With PVR and Inferior Breaks. NCT04168255 | Minia University | N/A |
| Completed | Inflammasomes in Cell Death in FTMH, ERM, and RRD NCT03332758 | Allen C. Ho, MD | — |
| Completed | Correlation of Metamorphopsia and Aniseikonia to Retinal Shift Following Retinal Detachment Surgery NCT03187613 | Helse Stavanger HF | — |
| Completed | Adaptive Optics in PVR NCT03551574 | Moorfields Eye Hospital NHS Foundation Trust | — |
| Unknown | A Study of a New Surgical Treatment of Macular Hole Retinal Detachment in High Myopia NCT03383731 | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | N/A |
| Completed | Evaluation of Visual Functions After Pars Plana Vitrectomy With and Without Internal Limiting Membrane Peeling NCT04139811 | Minia University | N/A |
| Completed | Internal Limiting Membrane Flap in the Management of Retinal Detachment Due to Paracentral Retinal Breaks NCT03707015 | San Ni Chen | — |
| Completed | Subconjunctiva Bupivacaine as Analgesia in Intravitreal Silicone Oil Removal NCT03046719 | Indonesia University | N/A |
| Completed | Randomized Controlled Trial of LUtein as a Novel Neuroprotective Adjunctive Therapy to Improve Visual Outcome NCT03932305 | Singapore National Eye Centre | N/A |
| Completed | The Posturing After Retinal Detachment (Post RD) Trial NCT02748538 | Moorfields Eye Hospital NHS Foundation Trust | — |
| Completed | High Myopia Macular Hole and Retinal Detachment Treated With Double ILM Flaps NCT03174639 | National Taiwan University Hospital | N/A |
| Completed | Functional and Morphological Results of Rhegmatogenous Retinal Detachment Treated With Vitrectomy NCT03902795 | Medical University of Lublin | — |
| Completed | Postoperative Pain After Vitreoretinal Surgery NCT03538847 | University of Florence | — |
| Completed | Proof of Concept - Digital Electro-optical Surgical Platform as Replacement for Operational Microscopes NCT02715388 | Elbit Systems LTD | N/A |
| Terminated | Prognostic Value of Hemodynamic Disturbances in Rhegmatogenous Retinal Detachment (CRADO-RED) NCT02618083 | Fondation Ophtalmologique Adolphe de Rothschild | N/A |
| Completed | Changes of Macular Pigment and Parameters of Eyes After YAG Laser Treatment in Cases With Capsule Opacificatio NCT03321253 | Afyon Kocatepe University Hospital | N/A |
| Completed | Bevacizumab Against Recurrent Retinal Detachment NCT02192970 | University of Wisconsin, Madison | Phase 2 |
| Completed | Early Vitrectomy for Endophthalmitis After Cataract Surgery NCT05249413 | Benha University | — |
| Completed | Prophylactic Laser Photocoagulation and Vitrectomy for Acute Retinal Necrosis NCT02222857 | National Taiwan University Hospital | — |
| Completed | Measurement of the Retinal Oxygen Saturaiton After Long-term Silicon Oil Tamponade NCT02423382 | Sun Yat-sen University | N/A |
| Terminated | A Study Testing if Medicine Can Make Pigment Epithelium Detachments Regress and Stabilize the Vision in Eyes NCT01746875 | Norwegian University of Science and Technology | N/A |
| Recruiting | DISCOVER Study: Microscope-integrated Intraoperative OCT Study NCT02423213 | The Cleveland Clinic | — |
| Unknown | The Influence of Postoperative Postures on Persistent Sub-foveal Fluid After Scleral Buckle Surgery NCT02294708 | Peking University Third Hospital | N/A |
| Completed | Scleral Self-indentation Chandelier-assisted Peripheral Vitrectomy Under Air Rhegmatogenous Retinal Detachment NCT03218371 | Dar El Oyoun Hospital | — |
| Unknown | Multi-electrocoagulation Retinectomy for Retinal Re-detachment in Silicone Oil Filled Eye NCT02201706 | Sun Yat-sen University | N/A |
| Completed | Eye Injections of Bevacizumab for Lowering Risk of Scar Tissue in the Retina and Repeated Retinal Detachment. NCT01860586 | Wills Eye | N/A |
| Completed | Postoperative Pain Control Following Vitreoretinal Surgery NCT01995045 | Emory University | Phase 4 |
| Completed | DOREFA (Retinal Detachment: Function and Anatomy) NCT01767038 | Centre Hospitalier Universitaire Dijon | N/A |
| Completed | PIONEER: Intraoperative and Perioperative OCT Study NCT02423161 | The Cleveland Clinic | — |
| Withdrawn | Study Trial of Dexamethasone Use for Alleviation of Symptoms After Scleral Buckle Eye Surgery NCT01326585 | University of Toronto | Phase 4 |
| Unknown | Evaluation of Neuroprotective Effect of Minocycline NCT01297816 | Shahid Beheshti University of Medical Sciences | Phase 2 |
| Completed | Comparative Study of 1000 Centistoke Versus 5000 Centistoke Silicone Oil for Repair of Complex Retinal Detachm NCT01255293 | Mid Atlantic Retina | N/A |
| Unknown | Flexibility, Efficacy, and Safety of a Foldable Capsular Vitreous Body in the Treatment of Severe Retinal Deta NCT01261533 | GuangZhou WeiShiBo Biotechnology Co., ltd | Phase 1 |
| Terminated | Rasagiline (Azilect) - Neuroprotection for Macula-off Retinal Detachment NCT02068625 | Insel Gruppe AG, University Hospital Bern | Phase 4 |
| Unknown | Double Endotamponade With Perfluorodecalin and Silicone Oil in Retinal Detachment Surgery. NCT01959568 | The S.N. Fyodorov Eye Microsurgery State Institution | N/A |
| Completed | Effect of Topical Aqueous Suppressants on Intraocular Gas Duration Following Pars Plana Vitrectomy NCT01257698 | Mid Atlantic Retina | N/A |
| Unknown | Adjunctive Local Application of Lidocaine During Scleral Buckling Under General Anesthesia NCT01417572 | Isfahan University of Medical Sciences | Phase 4 |
| Completed | Diagnosis of Posttraumatic Stress Disorder Following Primary Rhegmatogenous Retinal Detachment NCT01233908 | Sheba Medical Center | — |
| Completed | The Application of Fibrin Glue (Tissucol Duo Quick) in External Eye Surgeries NCT02138019 | National Taiwan University Hospital | N/A |
| Completed | Partial Posterior Hyaloidectomy in Macular Surgery NCT01454466 | Samsung Medical Center | Phase 1 |
| Completed | Dexmedetomidine Versus Propofol in Vitreoretinal Surgery NCT01001429 | Rutgers, The State University of New Jersey | Phase 4 |
| Completed | Avastin for PDR (Proliferative Diabetic Retinopathy) NCT01270542 | University of Southern California | N/A |
| Completed | The Exploratory Clinical Trials for the Feasibility, Primary Safety and Efficacy of Foldable Capsular Vitreous NCT00910702 | GuangZhou WeiShiBo Biotechnology Co., ltd | EARLY_Phase 1 |
| Completed | 23-gauge Pars Plana Vitrectomy With Silicone Oil Injectionsilicone Oil Injection With Surgical NCT04280770 | Ain Shams University | N/A |
| Completed | Anticoagulant and Antiplatelet Agents in Patients Undergoing Vitreoretinal Surgery NCT01020656 | Centre Hospitalier Universitaire Dijon | — |
| Completed | Ranibizumab for Diabetic Traction Retinal Detachment NCT01201161 | University of Sao Paulo | Phase 2 |
| Completed | 23 Gauge and 20 Gauge Vitrectomy for Rhegmatogenous Retinal Detachments NCT01716507 | Wills Eye | N/A |
| Completed | Pars Plana Vitrectomy (PPV) Versus Preoperative Intravitreal Bevacizumab Plus PPV to Treat Diabetic Tractional NCT00690768 | University of Sao Paulo | Phase 2 |
| Terminated | Pressurized PPV 23GA Vitrectomy in Complicated Diabetic Tractional Retinal Detachment NCT00404209 | Asociación para Evitar la Ceguera en México | Phase 3 |
| Withdrawn | Comparison High-density Silicone Oils in Retinal Detachment NCT00403702 | Asociación para Evitar la Ceguera en México | Phase 2 / Phase 3 |
| Completed | Pars Plana Vitrecromy in Patients Aged 85 Years and Above NCT03222362 | Tel Aviv Medical Center | — |
| Terminated | Efficient Study of ACULAR in Inhibiting Proliferative Retinopathy in Prematurity NCT00634972 | University of South Alabama | Phase 4 |
| Completed | Retinal Detachment After Lens Surgery in the Nearsighted NCT04072939 | University Hospital, Bordeaux | — |
| Completed | Pneumatic Retinopexy Versus Vitrectomy With Gas for Retinal Detachment Due to Myopic Macular Hole NCT00485199 | Peking University | N/A |
| Completed | Comparison of Air and Expansile Gas in Pneumatic Retinopexy NCT00120445 | Khon Kaen University | Phase 3 |
| Terminated | Study of Denufosol (INS37217) in Subjects With Rhegmatogenous Retinal Detachment NCT00083967 | Merck Sharp & Dohme LLC | Phase 2 |
| Completed | A Study in Subjects With Retinal Detachment NCT00210067 | Merck Sharp & Dohme LLC | Phase 1 |
| Completed | An Observational Study of Oral Fluoroquinolones and the Risk of Retinal Detachment NCT01881438 | Janssen Research & Development, LLC | — |
| Unknown | Short Term Postoperative Tamponade Using Perfluorocarbon Liquid for Giant Retinal Tears NCT01604616 | Ziv Hospital | — |
| Completed | The Silicone Study NCT00000140 | National Eye Institute (NEI) | Phase 3 |
| Completed | Diabetic Retinopathy Vitrectomy Study (DRVS) NCT00000154 | National Eye Institute (NEI) | Phase 3 |