NCT01326585

Study Trial of Dexamethasone Use for Alleviation of Symptoms After Scleral Buckle Eye Surgery

Effect of Dexamethasone on Postoperative Symptoms of Scleral Buckling Surgery Patients: a Randomized Control Trial

• Status: Withdrawn
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: University of Toronto · Academic / Other
• Sex: All
• Age: 18 Years – 79 Years
• Healthy volunteers: Not accepted

Summary

Dexamethasone is a medication that has been shown to have clear anti-nausea, anti-inflammatory, and painkilling properties. Dexamethasone is currently used to manage postoperative symptoms of a variety of surgical procedures. However, its effect has not been validated for scleral buckling surgery, which is used to treat retinal detachment, a medical emergency that can lead to permanent blindness. In this study, the investigators will randomly administer dexamethasone to half of scleral buckling surgery patients, and a placebo to the other half. The investigators will then compare the postoperative symptoms of the two groups in order to determine whether dexamethasone should be used for scleral buckling surgeries.

Conditions

• Retinal Detachment

Interventions

Type	Name	Description
DRUG	Dexamethasone Sodium Phosphate Injection	8mg (2cc of 4mg/mL solution), IV solution, 1-time dose during surgery
DRUG	Saline Injection	2cc of 0.9% normal saline, IV injection, 1-time dose during surgery

Timeline

• Start date: 2011-04-01
• Primary completion: 2012-03-01
• Completion: 2012-04-01
• First posted: 2011-03-31
• Last updated: 2015-06-03

Locations

2 sites across 1 country: Canada