Clinical Trials Directory

Trials / Terminated

TerminatedNCT00083967

Study of Denufosol (INS37217) in Subjects With Rhegmatogenous Retinal Detachment

A Randomized, Double-Masked, Placebo Controlled, Parallel Group, Multi-Center, Dose-Ranging Study of Denufosol Tetrasodium (INS37217) Intravitreal Injection in Subjects With Rhegmatogenous Retinal Detachment

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
23 (actual)
Sponsor
Merck Sharp & Dohme LLC · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to test if denufosol will remove the fluid build-up in the eye so that the retina can be re-attached without invasive surgery.

Detailed description

The purpose of this trial is to determine if administration of denufosol is well-tolerated and more efficacious than placebo in stimulating subretinal fluid reabsorption and retinal reattachment without surgical intervention in subjects presenting with rhegmatogenous retinal detachment.

Conditions

Interventions

TypeNameDescription
DRUGdenufosol tetrasodium (INS37217) Intravitreal Injection

Timeline

Start date
2004-06-01
Primary completion
2006-04-01
Completion
2006-04-01
First posted
2004-06-07
Last updated
2015-04-10

Locations

33 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00083967. Inclusion in this directory is not an endorsement.