Trials / Unknown
UnknownNCT03631108
Feasibility Study and Preliminary Application Study on Iris OCTA
Feasibility Study and Preliminary Application Study on Noninvasive Iris Optical Coherence Tomography Angiography (OCTA)
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 4,000 (estimated)
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Accepted
Summary
All participants will underwent imaging using the OCTA system (Zeiss) with the anterior segment optical adaptor lens. The main outcomes are iris blood flow density and vascular density.
Detailed description
1. Feasibility study of iris OCTA technology 2. Establishment of iris OCTA database in normal population and analysis of related factors: (1) different sex; (2) different age; (3) different myopic diopter; (4) 24-hour diurnal changes from morning to night; (5) before and after mydriasis; (6) different blood pressure; (7) different intraocular pressure; (8) different blood glucose; (9) before and after exercise. (10) drinking water, tea, coffee and red wine. 3. Analysis of iris OCTA data related to eye diseases:(1) conjunctivitis; (2) glaucoma; (3) childhood myopia; (4) uveitis; (5) diabetic retinopathy; (6) retinal detachment; (7) fundus neovascularization. 4. Influence of commonly used ophthalmic drops on iris OCTA data. Observe the difference of iris OCTA test data before and after treatment: (1) conjunctivitis treated with levofloxacin antibiotics; (2) glaucoma treated with prostaglandins, adrenalines and receptor blockers; (3) childhood myopia treated with atropine drugs (4) uveitis treated with hormonal drugs. (5) diabetic retinopathy treated with vasodilator. 5. Effect on iris OCTA data before and after ophthalmic surgery. (1) cataract, phacoemulsification + intraocular lens implantation; (2) glaucoma, iridectomy; (3) fundus neovascularization, intraocular injection of anti-VEGF; (4) diabetic retinopathy, vitreous surgery.
Conditions
- Conjunctivitis
- Glaucoma
- Myopia
- Diabetic Retinopathy
- Retinal Detachment
- Retinal Neovascularization, Unspecified
- Uveitis
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | OCTA (ZEISS) | All participants will underwent imaging using the OCTA system (Zeiss) with the anterior segment optical adaptor lens. |
Timeline
- Start date
- 2018-10-01
- Primary completion
- 2019-04-01
- Completion
- 2019-06-01
- First posted
- 2018-08-15
- Last updated
- 2018-09-06
Source: ClinicalTrials.gov record NCT03631108. Inclusion in this directory is not an endorsement.