| Not Yet Recruiting | Prevention of Reperfusion Injury Outcomes Through Effective Cardioprotection Targeting Myocardial Infarction NCT07362446 | Nyrada Pty Ltd | Phase 2 |
| Not Yet Recruiting | Head Cooling in Ischaemic Stroke Patients Undergoing Endovascular Thrombectomy (COOLHEAD-2b) NCT07526649 | Auckland City Hospital | N/A |
| Not Yet Recruiting | Effect Inhaled Nitric Oxide in Adult Liver Transplant NCT07125443 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Recruiting | Intracoronary Hypothermia as a Prevention of Reperfusion Injury in Myocardial Infarction. NCT06567249 | Tomsk National Research Medical Center of the Russian Academy of Sciences | N/A |
| Recruiting | Hydrogen's Feasibility and Safety as a Therapy in ECPR NCT05574296 | Boston Children's Hospital | Phase 1 |
| Completed | Investigation of the Protective Effect of Alpha Lipoic Acid on Ischemic Reperfusion Damage in Ischemic Priapis NCT07391709 | Trabzon Kanuni Education and Research Hospital | N/A |
| Completed | Ischemic Post-conditioning in Acute Ischemic Stroke Thrombectomy (PROTECT-1b) NCT05909982 | Capital Medical University | Phase 1 / Phase 2 |
| Unknown | Reperfusion With Hypothermia in Acute Ischemic Stroke NCT05676957 | Liping Liu | N/A |
| Completed | Combined Antioxidant Therapy Against Myocardial Reperfusion Injury. Phase I Study. NCT05215743 | University of Chile | Phase 1 |
| Unknown | Trial to Investigate the Effect of Dapagliflozin on Ischemia Reperfusion Induced Endothelial Dysfunction NCT05217654 | Medical University of Vienna | Phase 1 |
| Active Not Recruiting | Goal-directed CPR Using Cerebral Oximetry NCT04924985 | NYU Langone Health | N/A |
| Completed | Wet and Dry Biomarkers to Predict Secondary Injury in Stroke: From Bench to Bedside - The NIMBLE Study NCT07422636 | University of Florence | — |
| Unknown | A Trial of Intravascular Hypothermia Therapy in Acute Ischemic Stroke Patients NCT04695236 | jiaoliqun | N/A |
| Terminated | Cardiac Strain Using Speckle Tracking Echocardiography During Orthotopic Liver Transplantation NCT04316468 | Mayo Clinic | — |
| Unknown | Study of Cerebral Venous System in Acute Ischemic Stroke Patients Receiving Reperfusion Therapy NCT03838289 | Second Affiliated Hospital, School of Medicine, Zhejiang University | — |
| Completed | Remote Ischemic Conditioning as a Treatment for Traumatic Brain Injury NCT03176823 | Unity Health Toronto | N/A |
| Unknown | EUROpean Intracoronary Cooling Evaluation in Patients With ST-elevation Myocardial Infarction. NCT03447834 | Catharina Ziekenhuis Eindhoven | N/A |
| Completed | Hypothermic Oxygenated Machine Perfusion of Extended Criteria Kidney Allografts From Brain Death Donors NCT03378817 | University Hospital, Aachen | N/A |
| Completed | Remote Ischaemic PreConditioning (RIPC) in Partial Nephrectomy for the Prevention of Ischemia/Reperfusion Inju NCT03068689 | University Hospital, Basel, Switzerland | N/A |
| Unknown | Cardiac REperfusion With Intralipid® at Reperfusion NCT02807727 | Nkanyiso Hadebe | Phase 2 / Phase 3 |
| Completed | Splenic Artery Ligation and Portocaval Shunt in Small-for-size Syndrome NCT05459883 | Aretaieion University Hospital | — |
| Completed | Prognostic Value of Ventricular Fibrillation Spectral Analysis in Sudden Cardiac Death NCT03248557 | Hospital San Carlos, Madrid | — |
| Completed | Tolerance of Myocardium to Ischemia Injury NCT02812901 | University Hospital, Lille | N/A |
| Unknown | Acute Ischaemic STROKE: From LAboratory to the Patient's BED NCT05725694 | Istituto di Neuroscienze Consiglio Nazionale delle Ricerche | — |
| Unknown | Intra-graft Coagulation Events in Clinical Renal Transplantation and Delayed Graft Function NCT02568696 | Helsinki University Central Hospital | — |
| Terminated | Myocardial and Renal Dysfunction by Oxidative Stress Caused by Cardiac Surgery NCT02394405 | Moscow Regional Research and Clinical Institute (MONIKI) | — |
| Suspended | Pulmonary Protection of Transcutaneous Electrical Acupoint Stimulation in Gynecologic Laparoscopic Surgery NCT02850471 | Shengjing Hospital | Phase 1 / Phase 2 |
| Unknown | GLP-1 Loading During Elective Percutaneous Coronary Intervention NCT02127996 | Papworth Hospital NHS Foundation Trust | Phase 2 |
| Completed | Effect of Pneumoperitoneum on Human Ovary NCT02731651 | Ege University | N/A |
| Completed | Effects of Oxygen Treatment on Mechanisms Involved in Ischemia-reperfusion Injury: A Pilot Study in Healthy Vo NCT02286544 | Karolinska Institutet | Phase 1 |
| Completed | Combined Drug Approach to Prevent Ischemia-reperfusion Injury During Transplantation of Livers (CAPITL) NCT02251041 | Universitaire Ziekenhuizen KU Leuven | Phase 2 |
| Completed | Intestinal Ischemia as a Stimulus for Systemic Inflammatory Response After Cardiac Arrest NCT01944605 | Virginia Commonwealth University | — |
| Completed | Comparison of Oxidative Stress Changes in Different Ventilation Strategies During Gynecologic Laparoscopic Sur NCT02512640 | Chang Gung Memorial Hospital | N/A |
| Completed | Safety and Effectiveness of Intra-coronary Nitrite in Acute Myocardial Infarction NCT01584453 | Barts & The London NHS Trust | Phase 2 |
| Completed | Evaluation of Myocardial Effects of MTP-131 for Reducing Reperfusion Injury in Patients With Acute Coronary Ev NCT01572909 | Stealth BioTherapeutics Inc. | Phase 2 |
| Completed | Role of Adiponectin and Endothelial Progenitor Cells in Reperfusion Injury in Patients With Acute Myocardial I NCT01414452 | Universiteit Antwerpen | — |
| Withdrawn | Attenuating Ischemia Reperfusion Injury After Living Donor Renal Transplantation NCT01149993 | Georgetown University | Phase 4 |
| Unknown | Antenatal Allopurinol During Fetal Hypoxia NCT00189007 | UMC Utrecht | Phase 3 |
| Completed | Study to Evaluate if Inhaled Nitric Oxide Improves Liver Function After Transplantation NCT00582010 | University of Alabama at Birmingham | Phase 2 / Phase 3 |
| Completed | Study of High Dose Vitamin C On Outcome in Cardiac Surgery Patients NCT01167569 | Rutgers, The State University of New Jersey | Phase 4 |
| Completed | Clinical Trial of Remote Preconditioning in Patients Undergoing Cervical Decompression Surgery NCT00778323 | Xijing Hospital | Phase 1 / Phase 2 |
| Completed | Diagnostics for the Reperfusion Injury Following MI NCT00529607 | RWTH Aachen University | — |
| Completed | Magnesium Administration in Liver Transplantation and Reperfusion Injury NCT00994981 | The Catholic University of Korea | Phase 4 |
| Completed | Effect of Adjunctive Intracoronary Streptokinase on Late Term Left Ventricular Infarct Size and Volumes in Pat NCT00627809 | Istanbul University | Phase 4 |
| Completed | A Safety and Efficacy Study to Confirm the Cardioprotective Effects of MC-1 in Patients Undergoing High-Risk C NCT00402506 | Medicure | Phase 3 |
| Completed | Role of Volatile Anesthetics for Hepatic Protection NCT00516711 | University of Zurich | N/A |
| Completed | Myocardial Infarction Size Reduction With Atorvastatin NCT00286312 | R&D Cardiologie | Phase 4 |
| Completed | Protection of the Heart With Doxycycline During Coronary Artery Bypass Grafting NCT00246740 | University of Alberta | Phase 2 |
| Completed | MEND-CABG (MC-1 to Eliminate Necrosis and Damage in Coronary Artery Bypass Graft Surgery) NCT00157716 | Medicure | Phase 2 |
| Completed | N-acetylcysteine to Reduce Ischemia/Reperfusion Injury in Liver Resection NCT01223326 | Clinica Universidad de Navarra, Universidad de Navarra | Phase 4 |
| Completed | Pilot Study of Edaravone to Treat Acute Myocardial Infarction NCT00265239 | Kumamoto University | Phase 4 |