Trials / Completed
CompletedNCT00516711
Role of Volatile Anesthetics for Hepatic Protection
Role of Volatile Anesthetics for Hepatic Protection in Ischemia-reperfusion
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- —
- Sponsor
- University of Zurich · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Accepted
Summary
This study aims to evaluate the attenuation of ischemic-reperfusion injury in the liver after sevoflurane preconditioning. In the presence of sevoflurane, an attenuation of liver injury is hypothesized (diminished increase of liver enzymes, reduced production of inflammatory mediators).
Detailed description
Organ protection; preconditioning; volatile anesthetics; ischemia reperfusion
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Sevoflurane |
Timeline
- Start date
- 2006-03-01
- Primary completion
- 2007-12-01
- Completion
- 2007-12-01
- First posted
- 2007-08-15
- Last updated
- 2010-09-15
Locations
1 site across 1 country: Switzerland
Source: ClinicalTrials.gov record NCT00516711. Inclusion in this directory is not an endorsement.