Clinical Trials Directory

Trials / Conditions / Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndrome (MDS)

101 registered clinical trials studyying Myelodysplastic Syndrome (MDS)11 currently recruiting.

StatusTrialSponsorPhase
Not Yet RecruitingA Study of BLEX 404 Oral Liquid in Patients With International Prognostic Scoring System (IPSS) Intermediate-1
NCT02944955
BioLite, Inc.Phase 2
RecruitingPatient Reported Outcomes and Patient Voice Among Patients Diagnosed With Low Risk Myelodysplastic Syndrome (L
NCT07008820
Bristol-Myers Squibb
RecruitingA Phase 1B/2A Trial of NADUNOLIMAB in Combination With Azacitidine (With/Without Venetoclax) in Patients With
NCT06548230
M.D. Anderson Cancer CenterPhase 1 / Phase 2
RecruitingEffect of Moderate Renal Impairment and Race/Ethnicity on Treosulfan Pharmacokinetics
NCT05534620
medac GmbHPhase 1
CompletedA Study of PRT2527 as Monotherapy and in Combination With Zanubrutinib or Venetoclax in Participants With R/R
NCT05665530
Prelude TherapeuticsPhase 1
Enrolling By InvitationReduced Intensity Conditioning Regimens for Acute Myeloid Leukemia and Myelodysplastic Syndrome
NCT05674539
Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyPhase 3
CompletedA Study of Single and Multiple Dose Administration of LP-001 in Healthy Subjects
NCT06294275
Longbio PharmaPhase 1
CompletedRefine and Assess the Readability of Patient, Carer, and Clinician Treatment Preference in Myelodysplasia Ques
NCT05817331
Otsuka Australia Pharmaceutical Pty Ltd
TerminatedSTIMULUS MDS-US : Sabatolimab Added to HMA in Higher Risk MDS
NCT04878432
Novartis PharmaceuticalsPhase 2
TerminatedADCT-301 in Patients With R/R AML, MDS, or MDS/MPN
NCT04639024
Gwynn Long, M.D.Phase 2
RecruitingCLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)
NCT05143996
Cullinan Therapeutics Inc.Phase 1
SuspendedA Study to Investigate Fadraciclib (CYC065), in Subjects With Leukemia or Myelodysplastic Syndrome (MDS)
NCT05168904
Cyclacel Pharmaceuticals, Inc.Phase 1 / Phase 2
TerminatedStudy to Evaluate Adverse Events and Movement of Lemzoparlimab in Body When Used Intravenously (IV) With Azaci
NCT04912063
AbbViePhase 1
TerminatedA Study of Sabatolimab in Combination With Azacitidine and Venetoclax in High or Very High Risk MDS Participan
NCT04812548
Novartis PharmaceuticalsPhase 2
Active Not RecruitingStudy of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations
NCT04603001
Eli Lilly and CompanyPhase 1
RecruitingA Phase 1 Trial of ASTX030 in Patients With Myelodysplastic Syndrome
NCT04608110
Taiho Pharmaceutical Co., Ltd.Phase 1
Active Not RecruitingStudy Of Venetoclax Tablet With Intravenous or Subcutaneous Azacitidine to Assess Change in Disease Activity I
NCT04401748
AbbViePhase 3
CompletedTPO-Mimetic Use in Children for Hematopoietic Failure
NCT04478227
Anjali SharathkumarEARLY_Phase 1
UnknownJSP191 Antibody Conditioning Regimen in MDS/AML Subjects Undergoing Allogenic Hematopoietic Stem Cell Transpla
NCT04429191
Jasper Therapeutics, Inc.Phase 1
UnknownAntigen-specific T Cell Therapy for AML or MDS Patients With Relapsed Disease After Allo-HCT
NCT04284228
NexImmune Inc.Phase 1 / Phase 2
RecruitingA Clinical Trial of TQB3455 Tablets in Patients With Hematological Malignancies
NCT06550713
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.Phase 1
WithdrawnA Study of FF-10501-01 in Combination with Azacitidine in Patients with Myelodysplastic Syndrome
NCT03486353
Fujifilm Pharmaceuticals U.S.A., Inc.Phase 2
TerminatedCPX-351 Therapy for MDS After Hypomethylating Agent Failure
NCT03957876
Case Comprehensive Cancer CenterPhase 2
Active Not RecruitingVenetoclax Added to Fludarabine + Busulfan Prior to Transplant and to Maintenance Therapy for AML, MDS, and MD
NCT03613532
Jacqueline Garcia, MDPhase 1
CompletedA Phase 1 Study of AMV564 in Patients With Intermediate or High-Risk Myelodysplastic Syndromes
NCT03516591
Amphivena Therapeutics, Inc.Phase 1
TerminatedA Study of the Effect of Blood Stem Cell Transplant After Chemotherapy Alone in Patients With Fanconi Anemia
NCT03600909
Memorial Sloan Kettering Cancer CenterPhase 2
UnknownMyelodysplastic Syndrome--CDA-2 Hematological Improvement National Affirmation Study
NCT03335943
Chinese Society of HematologyPhase 4
RecruitingUnrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM
NCT03173937
National Heart, Lung, and Blood Institute (NHLBI)Phase 1 / Phase 2
CompletedRelapse Prophylaxis With N-803 for AML and MDS Pts Following Allo HSCT
NCT02989844
Masonic Cancer Center, University of MinnesotaPhase 2
CompletedPhase I Study of S64315 Administred Intravenously in Patients With Acute Myeloid Leukaemia or Myelodysplastic
NCT02979366
Institut de Recherches Internationales ServierPhase 1
TerminatedStudy of IRX5183 in Relapsed and Refractory Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrome
NCT02749708
Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsPhase 1
CompletedStem Cell Transplantation With NiCord® (Omidubicel) vs Standard UCB in Patients With Leukemia, Lymphoma, and M
NCT02730299
Gamida Cell ltdPhase 3
CompletedHLA-Mismatched Unrelated Donor Bone Marrow Transplantation With Post-Transplantation Cyclophosphamide
NCT02793544
Center for International Blood and Marrow Transplant ResearchPhase 2
UnknownMyelodysplasic Syndromes and Risk Factors for Infection
NCT02905552
Assistance Publique - Hôpitaux de Paris
Active Not RecruitingProvision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haplo
NCT02790515
St. Jude Children's Research HospitalPhase 2
TerminatedSingle Agent JNJ-56022473 in MDS and AML Patients FAILING HYPOMETHYLATING AGENT BASED THERAPY
NCT02992860
GWT-TUD GmbHPhase 2
TerminatedThe Rapid Study: Randomized Phase II Study To Expedite Allogeneic Transplant With Immediate Haploidentical Plu
NCT02648932
University of ChicagoPhase 2
WithdrawnSafety and Effectiveness Study of CPI-613 to Treat Refractory or Relapsed Leukemia and Myelodysplastic Syndrom
NCT01520805
Cornerstone PharmaceuticalsPhase 2
CompletedReduced-Intensity Conditioning (RIC) and Myeloablative Conditioning (MAC) for HSCT in AML/MDS
NCT02626715
Randy WindreichPhase 2
TerminatedMicrotransplantation to Treat Refractory or Relapsed Hematologic Malignancies in Younger Patients
NCT02433483
St. Jude Children's Research HospitalPhase 2
WithdrawnPhase II Study of 5-azacytidine Maintenance After Transplant for AML or MDS
NCT02204020
University of PittsburghPhase 2
WithdrawnPharmacokinetic and Pharmacodynamic Assessment of Treatment With CPX-351 (Cytarabine: Daunorubicin) Liposome f
NCT02269579
Jazz PharmaceuticalsPhase 2
CompletedDose-escalation Study of Oral Administration of S 055746 in Patients With Acute Myeloid Leukaemia or Myelodysp
NCT02920541
Institut de Recherches Internationales ServierPhase 1
UnknownPhase I Study of an Oncofetal Antigen Multi-Peptide Immunotherapy in Subjects With Hematologic Cancer
NCT02240537
Benovus Bio, Inc.Phase 1
TerminatedRepeat Transplantation for Relapsed or Refractory Hematologic Malignancies Following Prior Transplantation
NCT02259348
St. Jude Children's Research HospitalPhase 2
CompletedSelinexor With Fludarabine and Cytarabine for Treatment of Refractory or Relapsed Leukemia or Myelodysplastic
NCT02212561
St. Jude Children's Research HospitalPhase 1
CompletedA Phase 1/2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Hematologic and Myeloproliferative
NCT02158858
Constellation PharmaceuticalsPhase 1 / Phase 2
TerminatedA Safety and Tolerability Study of CDX-301 With or Without Plerixafor for Stem Cell Mobilization in Matched Re
NCT02200380
Celldex TherapeuticsPhase 2
CompletedAn Open Label Phase II Pharmacokinetic and Pharmacodynamic Assessment of the Potential for QTc Prolongation Fo
NCT02238925
Jazz PharmaceuticalsPhase 2
CompletedDarbepoetin Alfa MDS Companion Protocol
NCT02175277
AmgenPhase 3
TerminatedStudy of Azacitidine With or Without Birinapant in Subjects With MDS or CMMoL
NCT02147873
TetraLogic PharmaceuticalsPhase 2
RecruitingHSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy
NCT02143830
Children's Hospital Medical Center, CincinnatiPhase 2
UnknownStudy of ASC-101 in Patients With Hematologic Malignancies Who Receive Dual-cord Umbilical Cord Blood Transpla
NCT01983761
Targazyme, Inc.Phase 1 / Phase 2
CompletedTreosulfan/Fludarabine/Low Dose TBI as a Preparative Regimen for Children With AML/MDS Undergoing Allo HCT
NCT01772953
Center for International Blood and Marrow Transplant ResearchPhase 2
CompletedPhase II Hedgehog Inhibitor for Myelodysplastic Syndrome (MDS)
NCT01842646
H. Lee Moffitt Cancer Center and Research InstitutePhase 2
CompletedFeasibility and Outcomes of Allogeneic HCT Compared to Chemotherapy in Older AML Patients
NCT01929408
Fred Hutchinson Cancer Center
Active Not RecruitingCD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant
NCT02061800
Diane GeorgePhase 1 / Phase 2
CompletedUse of Hyperbaric Oxygen Therapy to Improve Umbilical Cord Blood Stem Cell Homing and Subsequent Engraftment
NCT02099266
University of Kansas Medical CenterN/A
CompletedTransplantation of NiCord®, Umbilical Cord Blood-derived Ex Vivo Expanded Cells, in Patients With HM
NCT01816230
Gamida Cell ltdPhase 1 / Phase 2
CompletedBone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders
NCT01758042
Massachusetts General HospitalN/A
CompletedAML-MDS Novel Prognostic Tests Clinical Study
NCT01685619
Nova Scotia Health Authority
CompletedStudy of Azacitidine to Evaluate Safety and Effectiveness for Chinese Patients With Higher Risk Myelodysplasti
NCT01599325
CelgenePhase 2
CompletedSafety and Efficacy of POL6326 for Mobilization/Transplant of Sibling Donor in Patients With Hematologic Malig
NCT01413568
Polyphor Ltd.Phase 1 / Phase 2
CompletedImproving Blood Stem Cell Collection and Transplant Procedures
NCT01517035
National Heart, Lung, and Blood Institute (NHLBI)Phase 1 / Phase 2
UnknownVidaza and Valproic Acid Post Allogeneic Transplant for High Risk AML and MDS
NCT02124174
Patrick StiffPhase 2
TerminatedPhase 2 Study of Telintra® in Deletion 5q Myelodysplastic Syndrome
NCT01422486
TelikPhase 2
TerminatedStudy of (Telintra®) in Non-Del(5q) Myelodysplastic Syndrome
NCT01459159
TelikPhase 2
CompletedShorter Course Tacrolimus After Nonmyeloablative, Related Donor BMT With High-dose Posttransplantation Cycloph
NCT01342289
Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsPhase 1
TerminatedEltrombopag in Myelodysplastic Syndrome (MDS) Patients With Thrombocytopenia
NCT01286038
H. Lee Moffitt Cancer Center and Research InstitutePhase 1
TerminatedPhase I Study Evaluating TXA127 in Low/Intermediate-1 Risk Myelodysplastic Syndrome and Thrombocytopenia
NCT01362036
Tarix PharmaceuticalsPhase 1
CompletedStudy of Vidaza (Azacitidine) Versus Support Treatment in Patients With Low Risk Myelodysplastic Syndrome (Low
NCT01338337
Asociación Andaluza de Hematología y HemoterapiaPhase 2
CompletedPilot Study Evaluating Safety & Efficacy of DCBT: NiCord® & UNM CBU to Patients With Hematological Malignancie
NCT01221857
Gamida Cell ltdPhase 1 / Phase 2
SuspendedStudy of KB004 in Subjects With Hematologic Malignancies (Myelodysplastic Syndrome, MDS, Myelofibrosis, MF)
NCT01211691
Humanigen, Inc.Phase 1 / Phase 2
TerminatedLBH589 Alone or in Combination With Erythropoietin Stimulating Agents (ESA) in Patients With Low or Int-1 Risk
NCT01034657
Novartis PharmaceuticalsPhase 2
TerminatedEfficacy and Tolerability of the Combination of Valproic Acid and Lenalidomide in the Treatment of Patients Wi
NCT00977132
Heinrich-Heine University, DuesseldorfPhase 2
CompletedTraditional Chinese Medicine in the Supportive Management of Anaemic and Cytopenic (Leukopenia, Thrombocytopen
NCT01224496
Singapore General HospitalPhase 1 / Phase 2
TerminatedHaploidentical Allogeneic Transplant With Post-transplant Infusion of Regulatory T-cells
NCT01050764
Everett MeyerPhase 1 / Phase 2
CompletedTreosulfan, Fludarabine Phosphate, and Total-Body Irradiation in Treating Patients With Hematological Cancer W
NCT00796068
Fred Hutchinson Cancer CenterPhase 2
CompletedMRI Screening for Patients With Myelodysplastic Syndrome (MDS), Who Have Received Multiple Red Blood Cell Tran
NCT00749372
Weill Medical College of Cornell UniversityN/A
TerminatedPhase 2 Study of Azacitidine (Vidaza) vs MGCD0103 vs Combination in Elderly Subjects With Newly Diagnosed Acut
NCT00666497
Mirati Therapeutics Inc.Phase 2
CompletedPhase 2 Study Comparing Two Dose Schedules of Telintra™ in Myelodysplastic Syndrome (MDS)
NCT00700206
TelikPhase 2
CompletedPhase II Study of Idarubicin, Cytarabine, and Vorinostat With High-Risk Myelodysplastic Syndrome (MDS) and Acu
NCT00656617
M.D. Anderson Cancer CenterPhase 2
TerminatedTreatment of Elderly Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic (MD) Syndrome Wi
NCT00655395
Viron Therapeutics IncPhase 1 / Phase 2
CompletedA Phase I Study of Lintuzumab Combined With Lenalidomide in Patients With Myelodysplastic Syndromes (MDS)
NCT00502112
Seagen Inc.Phase 1
CompletedWilm's Tumor 1 Protein Vaccine to Treat Cancers of the Blood
NCT00923910
National Cancer Institute (NCI)Phase 1 / Phase 2
CompletedMismatched Family Member Donor Transplantation for Children and Young Adults With High Risk Hematological Mali
NCT00566696
St. Jude Children's Research HospitalPhase 2
TerminatedRabbit Anti-thymocyte Globulin in the Treatment of Patients With Low to Intermediate-1 Risk Myelodysplastic Sy
NCT00542828
Genzyme, a Sanofi CompanyPhase 2
CompletedSafety of ON 01910.Na in Patients With Myelodysplasia
NCT00533416
National Heart, Lung, and Blood Institute (NHLBI)Phase 1
TerminatedPhase 1 Study of Terameprocol (EM-1421) in Patients With Leukemia
NCT00664677
Erimos PharmaceuticalsPhase 1
CompletedUnrelated Cord Blood Transplant Plus a Haplo-Identical (Half-Matched), T-Cell Depleted Stem Transplant From a
NCT00673114
Joanne Kurtzberg, MDPhase 1 / Phase 2
CompletedPeptide Vaccinations to Treat Patients With Low-Risk Myeloid Cancers
NCT00488592
National Heart, Lung, and Blood Institute (NHLBI)Phase 2
TerminatedA Phase I Study of WT1 Peptides to Induce Anti-Leukemia Immune Responses Following Transplantation
NCT00672152
Michael Morse, MDPhase 1
CompletedSerial Analysis of Chimerism in Patients With Refractory Cytopenia (RC) Transplanted With Reduced Intensity Co
NCT00682799
Charlotte Niemeyer, MD
Completed5-azacytidine Valproic Acid and ATRA in AML and High Risk MDS
NCT00339196
Assistance Publique - Hôpitaux de ParisPhase 2
CompletedStudy of TLK199 Tablets in Myelodysplastic Syndrome (MDS)
NCT00280631
TelikPhase 1 / Phase 2
CompletedSafety of Peptide Vaccination for Patients With Myelodysplastic Syndrome
NCT00270452
National Heart, Lung, and Blood Institute (NHLBI)Phase 1
UnknownMDS-CAN: A Prospective National MDS Clinical Database and Local Tissue Bank
NCT02537990
Sunnybrook Health Sciences Centre
Enrolling By InvitationBiology Studies of Hematologic Cancers
NCT00923442
National Cancer Institute (NCI)
TerminatedPhase II Research Study of Arsenic Trioxide (Trisenox) in Patients With Myelodysplastic Syndrome (MDS)
NCT00225992
Oncology Specialties, AlabamaPhase 2
CompletedHaploidentical Stem Cell Transplant for Treatment Refractory Hematological Malignancies
NCT00145613
St. Jude Children's Research HospitalPhase 2
CompletedHaploidentical Stem Cell Transplantation for Patients With Hematologic Malignancies
NCT00186823
St. Jude Children's Research HospitalPhase 3