Trials / Sponsors / Prelude Therapeutics
Prelude Therapeutics
Industry · 12 registered clinical trials — 1 currently recruiting.
| Status | Trial | Phase | Started |
|---|---|---|---|
| Recruiting | A Phase 1 Study of PRT12396 in Participants With Select Myeloproliferative Neoplasms Polycythemia Vera (PV), Myelofibrosis (MF), Myeloproliferative Neoplasms (MPNs) | Phase 1 | 2026-04-01 |
| Terminated | A Study of PRT3789 in Combination With Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors With Advanced Solid Tumor, Esophageal Cancer, Metastatic Solid Tumor | Phase 2 | 2025-06-03 |
| Terminated | A Study of PRT7732, an Oral SMARCA2 Degrader, in Patients With Advanced or Metastatic Solid Tumors With a SMAR Advanced Solid Tumor, Metastatic Solid Tumor, Non-small Cell Lung Carcinoma | Phase 1 | 2024-11-04 |
| Completed | A Study of PRT2527 as Monotherapy and in Combination With Zanubrutinib or Venetoclax in Participants With R/R Aggressive B-Cell Non-Hodgkin's Lymphoma (NHL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL), Mantle Cell Lymphoma (MCL) | Phase 1 | 2023-09-12 |
| Completed | PRT3789 Monotherapy and in Combo w/Docetaxel in Participants w/Advanced or Metastatic Solid Tumors w/SMARCA4 M Advanced Solid Tumor, Metastatic Solid Tumor, Non-small Cell Lung Cancers | Phase 1 | 2023-05-02 |
| Completed | A Study of PRT3645 in Participants With Select Advanced or Metastatic Solid Tumors Breast Cancer, Glioblastoma, Head and Neck Squamous Cell Carcinoma | Phase 1 | 2022-12-27 |
| Terminated | PRT1419 as Monotherapy or in Combination With Azacitidine or Venetoclax in R/R Myeloid or B-cell Malignancies Acute Myeloid Leukemia, B-cell Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia | Phase 1 | 2022-03-22 |
| Completed | A Study of PRT2527 in Participants With Advanced Solid Tumors Sarcoma, Castrate Resistant Prostate Cancer, Hormone Receptor Positive HER2 Negative Breast Cancer | Phase 1 | 2022-02-14 |
| Completed | A Study of PRT1419 in Patients With Advanced Solid Tumors Sarcoma, Melanoma, Lung Cancer | Phase 1 | 2021-08-11 |
| Completed | A Study of PRT1419 in Patients With Relapsed/Refractory Hematologic Malignancies Multiple Myeloma, Acute Myeloid Leukemia, Non Hodgkin Lymphoma | Phase 1 | 2020-09-28 |
| Completed | A Study of PRT811 in Participants With Advanced Solid Tumors, CNS Lymphoma and Gliomas Advanced Solid Tumor, Recurrent Glioma | Phase 1 | 2019-11-06 |
| Completed | A Study of PRT543 in Participants With Advanced Solid Tumors and Hematologic Malignancies Relapsed/Refractory Advanced Solid Tumors, Relapsed/Refractory Diffuse Large B-cell Lymphoma, Relapsed/Refractory Myelodysplasia | Phase 1 | 2019-02-11 |