| Not Yet Recruiting | Dexamethasone Regimens for BPD Prevention in Preterm Infants NCT07052201 | The Children's Hospital of Zhejiang University School of Medicine | Phase 3 |
| Recruiting | Personalized Music Therapy for Preterm Infants NCT07295106 | Fabrizio Faina | N/A |
| Not Yet Recruiting | Fentanyl Intranasal for Retinopathy of Prematurity Screening in Preterm Infants NCT07112430 | IWK Health Centre | Phase 1 / Phase 2 |
| Not Yet Recruiting | Global Survey on Newborns' HOspitalisation and Parental Experiences - the HOPE Study NCT06827028 | Global Foundation for the Care of Newborn Infants | — |
| Not Yet Recruiting | Heterogeneity Index in Neonatologist-performed Lung Ultrasound in Neonates Receiving Respiratory Support - a P NCT07117513 | Medical University of Graz | — |
| Recruiting | Effect of Developmental Care on Comfort, Growth, and Oral Feeding Transition in Preterm Infants NCT07045402 | Fenerbahce University | N/A |
| Not Yet Recruiting | Effects of an Information-Based Discharge Service on Preterm Infants, Parents, and Hospitals NCT06613386 | The First Affiliated Hospital with Nanjing Medical University | N/A |
| Unknown | Baby-CINO: CaffeINe Treatment Optimisation in Premature Infants NCT06416956 | University of Oxford | — |
| Unknown | The Effect of Physical Therapy Intervention on Motor Performance in Bhutanese Preterm Infants NCT06109350 | JDWNRH | N/A |
| Unknown | The Comparison of Gentle Human Touch's Effect by Mother and Nurse on Pain Level During Heel Blood Sampling in NCT05857423 | Istanbul University - Cerrahpasa | N/A |
| Unknown | Serial Lung Ultrasound Predicting Need for Surfactant and Respiratory Course in Preterm Infants Observational NCT05782569 | South Tees Hospitals NHS Foundation Trust | — |
| Unknown | The Effect of Hypnotherapeutic Sound-files on the Sleep of Parents in the Neonatal Unit. NCT05808088 | University of Aarhus | N/A |
| Active Not Recruiting | Measuring Diaphragm Electrical Activity in Neonates Using a Smaller Inter-electrode Distance NCT05427929 | Mount Sinai Hospital, Canada | N/A |
| Recruiting | Extremely Preterm Respiratory Outcome Cohort NCT06726226 | Seoul National University Hospital | — |
| Unknown | Role of Urinary Claudin-2, Caveolin-1, and EGF as Diagnostic Biomarkers of Necrotizing Enterocolitis in Preter NCT05335577 | University of Brawijaya | — |
| Completed | Telerehabilitation for Preterm Infants NCT07068386 | Hacettepe University | N/A |
| Completed | Non-Nutritive Sucking vs Non-Nutritive Sucking Combined With Breast Milk on the Neonatal Comfort NCT05097495 | Acibadem University | N/A |
| Completed | Feasibility of Use of the PATH bCPAP and Oxygen Blenders Device With Neonates in Uganda NCT05462509 | PATH | N/A |
| Terminated | Maintaining Optimal HVNI Delivery Using Automatic Titration of Oxygen in Preterm Infants NCT05030012 | Vapotherm, Inc. | N/A |
| Completed | Effect of Baby Massage on Oral Motor Skills of Premature Babies NCT06308471 | Ege University | N/A |
| Unknown | Personalized vs Standardized PN for Preterm Infants >1250g NCT03693287 | Ospedali Riuniti Ancona | Phase 4 |
| Completed | NEOVIDEO : Impact of Monitoring Motor Activity by Video Analysis on the Sleep of Very Preterm Infants NCT04624347 | Rennes University Hospital | N/A |
| Completed | Ibuprofen vs Expectant Management for hsPDA in Preterm Infants: Retrospective Cohort NCT07533721 | Shengjing Hospital | — |
| Completed | Preemie Prep For Parents (P3): Home Antenatal Prematurity Education NCT04093492 | Medical College of Wisconsin | N/A |
| Terminated | L-citrulline and Pulmonary Hypertension Associated With Bronchopulmonary Dysplasia NCT03542812 | University of Utah | EARLY_Phase 1 |
| Withdrawn | Cardboard Cot: Prevention of Moderate or Severe Hypothermia in Preterm Infants Assigned to Open Crib NCT03344991 | University of Alabama at Birmingham | N/A |
| Withdrawn | Cardboard Cot in Neonatal Thermoregulation: A Randomized Cross Over Trial NCT03344978 | University of Alabama at Birmingham | N/A |
| Terminated | Nasal High-frequency Jet Ventilation (nHFJV) Following Extubation in Preterm Infants NCT03558737 | University of Utah | N/A |
| Active Not Recruiting | Management of the PDA Trial NCT03456336 | NICHD Neonatal Research Network | Phase 3 |
| Terminated | The Alberta BLOOM Preterm Neonate Study NCT03840980 | University of Calgary | — |
| Completed | Applying Prechtl's Assessment of General Movements for Preterm Infants Through Telemedicine NCT03742635 | University of California, Davis | N/A |
| Completed | Effect of a Vibratory Stimulus on Mitigating Nociception-specific Responses to Skin Puncture in Neonates NCT04050384 | Lance M Relland, MD, PhD | N/A |
| Completed | Evaluation of a Peer Counseling Breastfeeding Support Program for Mother-preterm Infant Dyads NCT03156946 | Hospices Civils de Lyon | N/A |
| Completed | Improving Right Ventricular Function in Young Adults Born Preterm NCT03696758 | University of Wisconsin, Madison | Phase 2 |
| Active Not Recruiting | Serial Assessment of Body Fat Accrual in Very Preterm Infants NCT03575897 | University of Alabama at Birmingham | N/A |
| Completed | Oxygenation Instability and Maturation of Control of Breathing in Premature Infants NCT03445689 | University of Miami | — |
| Completed | The Effect of Replacement Frequency of Electrodes on Skin in Infant NCT05016167 | Acibadem University | N/A |
| Completed | Comparison of Leakage With Nasal Prongs and Nasal Mask Interface in Newborns Receiving CPAP Treatment NCT03586856 | Baldvin Jonsson | N/A |
| Active Not Recruiting | Effects of Closed-loop Automatic Control of FiO2 in Extremely Preterm Infants NCT03168516 | University Hospital Tuebingen | Phase 3 |
| Completed | Prematurity Related Ventilatory Control (PRE-VENT) - Specific Aim 3 NCT03333174 | University of Alabama at Birmingham | N/A |
| Completed | Prematurity Related Ventilatory Control (PRE-VENT) - Specific Aim 2 NCT03333161 | University of Alabama at Birmingham | N/A |
| Terminated | Enteral Zinc to Improve Growth in Infants at Risk for Bronchopulmonary Dysplasia NCT03532555 | University of Utah | N/A |
| Completed | Prematurity-Related Ventilatory Control: Role in Respiratory Outcomes NCT03174301 | University of Virginia | — |
| Completed | Parent-child Interactions, Child Developmental Health, and Health System Costs at 6 Months Corrected Age NCT03357458 | University of Calgary | N/A |
| Unknown | Efficacy of Adding Budesonide to Poractant Alfa to Prevent Bronchopulmonary Dysplasia. NCT03521063 | Hospital Central "Dr. Ignacio Morones Prieto" | Phase 4 |
| Completed | RAM Cannula VS Short Nasal Prongs for Delivering NIPPV in Preterm Infants NCT03081611 | Rambam Health Care Campus | N/A |
| Unknown | Impact of Protein Supplementation to Mother Milk on Resting Energy Expenditure (REE) in Growing Healthy Preter NCT03501485 | Tel-Aviv Sourasky Medical Center | — |
| Completed | Counseling for Prematurity Using a Multimedia Education Tool NCT03225885 | Medical College of Wisconsin | N/A |
| Completed | Cardiac Function and Metabolism in Young Adults Born Premature (PET-MRI) NCT03245723 | University of Wisconsin, Madison | N/A |
| Completed | Movement-based Infant Intervention NCT03082313 | University of Southern California | N/A |
| Completed | Novel Echocardiographic Methods for Early Identification of Neonates at Risk for Chronic Pulmonary Hypertensio NCT04402645 | Mount Sinai Hospital, Canada | — |
| Completed | Nifty Feeding Cup Versus Generic Medicine Cup Preterm Infants Who Have Difficulty Breastfeeding NCT03280381 | PATH | N/A |
| Completed | Non-nutritive Sucking and Breastfeeding in Preterm Infants NCT03434743 | Dr. Sandra Fucile | N/A |
| Completed | Heart Rate Evaluation and Resuscitation Trial in Preterm Neonates NCT03133663 | University of Texas Southwestern Medical Center | N/A |
| Completed | Pacifier Activated Device and Mother's Voice in Infants at High-risk for Cerebral Palsy NCT03230032 | Nationwide Children's Hospital | N/A |
| Completed | Early Skin to Skin in Neonatal Reanimation NCT03171844 | Centre Hospitalier Universitaire de Nice | N/A |
| Active Not Recruiting | Influence of Intestinal Microbiota Implantation in Preterm Infants on Microbiota and Immune Orientation at 3 Y NCT02738411 | Centre Hospitalier Universitaire de Nīmes | — |
| Completed | Monitoring of Systemic or Organ Perfusion for Preterm Infants NCT03136172 | Inha University Hospital | — |
| Completed | Brain Volumes of Very Low Birth Weight Infants Measured by Cranial Ultrasonography NCT02848755 | Zekai Tahir Burak Women's Health Research and Education Hospital | — |
| Unknown | Preliminary Study to the Conception of a Non-invasive Neonatal Monitoring System With Development of a Databas NCT02863978 | Rennes University Hospital | N/A |
| Terminated | Breastfeeding Infants Receiving Respiratory Support Trial NCT02999165 | Imperial College Healthcare NHS Trust | — |
| Completed | Language and Motricity in Preterm School Age Children NCT02811029 | University Hospital, Rouen | N/A |
| Completed | Impact of Oropharyngeal Administration of Colostrum in the First 48 Hours of Life Term Premature Newborn ≤ 32 NCT02650167 | Centre Hospitalier Universitaire de Nice | N/A |
| Completed | Study of the Impact of Administering t the Scale of Brazelton on the Mother's Confidence in Her Newborn Born P NCT02673385 | University Hospital, Limoges | — |
| Completed | Bilirubin Binding Capacity to Assess Bilirubin Load in Preterm Infants NCT02691156 | Stanford University | — |
| Completed | Comparison of NIV-NAVA vs. N-CPAP After Extubation in Preterm Infants Study NCT02590757 | Seoul National University Hospital | N/A |
| Terminated | Testosterone and Cortisol Levels in Infants NCT02599545 | Duke University | — |
| Completed | Splanchnic and Renal Tissue Oxygenation During Enteral Feedings in Neonates With Patent Ductus Arteriosus NCT03551600 | University of Utah | — |
| Completed | The Effects of Family Centered Intervention Program on Preterm Infants NCT03146351 | Gazi University | N/A |
| Completed | Metabolic Effects of Choline and Docosahexaenoic Acid Supplementation in Preterm Infants NCT02509728 | University Hospital Tuebingen | N/A |
| Completed | Effects of the Oral Stimulation Program in Extreme Preterm Infants NCT03025815 | Hospital de Clinicas de Porto Alegre | N/A |
| Completed | Randomized Controlled Trial of Higher-Volume Feedings in Preterm Neonates NCT02377050 | University of Alabama at Birmingham | N/A |
| Completed | Respiratory Dynamics During Birth Stabilization in Preterm Infants Less Than 32+6/7 Weeks Gestation NCT02748720 | Manuel Sanchez Luna | N/A |
| Completed | Determining an Optimal Weaning Method of Nasal Continuous Positive Airway Pressure in Preterm Neonates NCT02064712 | University of Texas Southwestern Medical Center | N/A |
| Completed | Minor Increase Over Minimal Risk Research in NICU NCT02482012 | Christiana Care Health Services | — |
| Completed | Aspiration of Residual Gastric Contents NCT01863043 | University of Florida | N/A |
| Completed | Less Invasive Beractant Administration in Preterm Infants NCT02611284 | Hospital General Universitario Gregorio Marañon | N/A |
| Completed | Prospective Evaluation of the Efficacy of Palivizumab Administration in Children Born at 29-32 Weeks of Gestat NCT01269528 | Rambam Health Care Campus | — |
| Completed | Development of Maternal Voice Recognition in Preterm Neonates NCT02818595 | Centre Hospitalier Universitaire, Amiens | N/A |
| Completed | SafeBoosC - a Phase II Trial NCT01590316 | Gorm Greisen | N/A |
| Terminated | Registration and Treatment of Pain During Eye Examination of Prematurity NCT01552993 | St. Olavs Hospital | N/A |
| Withdrawn | Use of Prokinetics in Early Enteral Feeding in Preterm Infants NCT01569633 | East Tennessee State University | N/A |
| Completed | Hydrocortisone for BPD NCT01353313 | NICHD Neonatal Research Network | Phase 3 |
| Completed | Breastfeeding Preterm Infants - The Efficacy of Internet-based Peer Support NCT02580786 | University of Turku | N/A |
| Completed | Vitamin E for Extremely Preterm Infants NCT01193270 | NICHD Neonatal Research Network | Phase 1 |
| Completed | Laparotomy vs. Drainage for Infants With Necrotizing Enterocolitis NCT01029353 | NICHD Neonatal Research Network | N/A |
| Completed | Multi-dose Pharmacokinetics and Dose Ranging of Inositol in Premature Infants (INS-2) NCT01030575 | NICHD Neonatal Research Network | Phase 2 |
| Withdrawn | Heparin Versus no Heparin on Duration of Peripherally Inserted Central Catheter (PICC) Patency in Neonates NCT00879957 | The University of Texas Health Science Center at San Antonio | N/A |
| Unknown | Recombinant Erythropoietin for Neuroprotection in Very Preterm Infants NCT00910234 | China Medical University Hospital | Phase 1 / Phase 2 |
| Completed | Early Blood Pressure Management in Extremely Premature Infants NCT00874393 | NICHD Neonatal Research Network | Phase 1 |
| Completed | Cerebral Function Monitoring in Premature Infants NCT00873847 | NICHD Neonatal Research Network | — |
| Completed | Urine NT-proBNP Levels and Echocardiographic Findings in Very Low Birth Weight (VLBW) Infants NCT00799123 | Charite University, Berlin, Germany | — |
| Completed | A Study on the Effects of Feeding and Feeding Methods on Breathing Pattern in Very Low Birth Weight Preterm In NCT00607555 | Sunnybrook Health Sciences Centre | — |
| Withdrawn | Use of NAVA in Intubated Preterm NCT00536445 | Sunnybrook Health Sciences Centre | Phase 1 / Phase 2 |
| Completed | Influenza Vaccine in Premature Infants NCT00455169 | University of Rochester | — |
| Terminated | High-Dose Erythropoietin in Extremely Premature Infants to Prevent/Attenuate Brain Injury: A Phase II Study NCT00589953 | Atlantic Health System | Phase 2 |
| Completed | Comparing IM vs. Vaginal Progesterone for Pre-term Birth NCT00579553 | University of Oklahoma | N/A |
| Completed | Nasogastric Tube vs. Orogastric Feeding Tube in Preterm Infants: Which is Best? NCT00365703 | Hillel Yaffe Medical Center | N/A |
| Completed | Neural Control of Non-invasive Ventilation in the Preterm NCT00368485 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Phase 1 |
| Completed | Single-Dose Intravenous Inositol Pharmacokinetics in Preterm Infants NCT00349726 | NICHD Neonatal Research Network | Phase 2 |
| Completed | Consequences of Parenteral Nutrition Photoprotection on Oxidant Related Diseases Among Extremely Low Birth Wei NCT00328419 | Hospices Civils de Lyon | N/A |
| Completed | Early-Onset Sepsis Surveillance Study NCT00874367 | NICHD Neonatal Research Network | — |
| Terminated | The Impact of Implementing NIDCAP on Preterm Infants in the NICU NCT00179933 | Ann & Robert H Lurie Children's Hospital of Chicago | N/A |
| Completed | Plasma B-Type Natriuretic Peptide Concentrations in Preterm Infants < 28 Weeks NCT00528736 | Charite University, Berlin, Germany | — |
| Completed | Physiologic Definition of Bronchopulmonary Dysplasia NCT01223287 | NICHD Neonatal Research Network | — |
| Terminated | Structural Brain Abnormalities in Children Born Prematurely: New Detection Methods and Clinical-Pathological C NCT00153855 | Children's Hospital of Philadelphia | — |
| Completed | Nasogastric Tube in Premature Babies - Pain and Treatment NCT00218946 | Norwegian University of Science and Technology | Phase 2 |
| Completed | Randomized Trial of Nasal Continuous Positive Airway Pressure or Synchronized Nasal Ventilation in Premature I NCT00188968 | University of Manitoba | Phase 3 |
| Completed | Immunogenicity of PCV-7 Vaccine in VLBW Infants NCT00273325 | NICHD Neonatal Research Network | — |
| Completed | Early Diagnosis of Candidiasis in Premature Infants NCT00109525 | NICHD Neonatal Research Network | — |
| Completed | Assessment of the Pulmonary Diffusion Capacity in Healthy Infants and Infants With Chronic Lung Disease NCT00428038 | Indiana University | — |
| Terminated | A Study of Cisapride in Premature Infants With Feeding Problems NCT01281566 | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | Phase 4 |
| Completed | Obstetrics and Periodontal Therapy (OPT) Study NCT00066131 | University of Minnesota | Phase 3 |
| Completed | Trial of Aggressive Versus Conservative Phototherapy in Infants <1,000 Grams Birth Weight NCT00114543 | NICHD Neonatal Research Network | Phase 3 |
| Completed | Delivery Room CPAP in Extremely Low Birth Weight Infants NCT01223274 | NICHD Neonatal Research Network | Phase 1 / Phase 2 |
| Completed | Metoclopramide Use in Very Low Birth Weight Newborns NCT00242450 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Phase 4 |
| Completed | Observational Study of Surgical Treatment of Necrotizing Enterocolotis NCT01223261 | NICHD Neonatal Research Network | — |
| Completed | Benchmarking Initiative to Reduce Bronchopulmonary Dysplasia NCT00067613 | NICHD Neonatal Research Network | N/A |
| Terminated | Inhaled Nitric Oxide for Preterm Infants With Severe Respiratory Failure NCT00016523 | NICHD Neonatal Research Network | Phase 3 |
| Completed | Delayed Cord Clamping in VLBW Infants NCT01222364 | NICHD Neonatal Research Network | Phase 1 / Phase 2 |
| Unknown | Vitamin A Supplementation in Preterm Infants NCT00063596 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | N/A |
| Completed | Inflammatory Cytokines Associated With Perinatal Brain Injury NCT01035697 | NICHD Neonatal Research Network | — |
| Completed | Glutamine Supplementation to Prevent Death or Infection in Extremely Premature Infants NCT00005775 | NICHD Neonatal Research Network | Phase 3 |
| Completed | The Edmonton Randomised Controlled Trial of NIDCAP - Based Developmental Care NCT00552383 | University of Alberta | N/A |
| Terminated | Minimal Breathing Support and Early Steroids to Prevent Chronic Lung Disease in Extremely Premature Infants (S NCT00005777 | NICHD Neonatal Research Network | Phase 3 |
| Completed | The Effects of Erythropoietin (EPO) on the Transfusion Requirements of Very Low Birth Weight Infants NCT01203514 | NICHD Neonatal Research Network | Phase 2 / Phase 3 |
| Completed | In Utero Magnesium Sulfate Exposure: Effects on Extremely-Low-Birth-Weight Infants NCT01203501 | NICHD Neonatal Research Network | — |
| Completed | Vitamin A Supplementation for Extremely-Low-Birth-Weight Infants NCT01203488 | NICHD Neonatal Research Network | Phase 1 / Phase 2 |
| Completed | Growth Observational Study NCT01203475 | NICHD Neonatal Research Network | — |
| Completed | Development of Standards for the New Ballard Maturation Score NCT01203449 | NICHD Neonatal Research Network | — |
| Completed | Supplemental Therapeutic Oxygen for Prethreshold Retinopathy of Prematurity NCT01203436 | NICHD Neonatal Research Network | Phase 2 / Phase 3 |
| Completed | Trial of Indomethacin Prophylaxis in Preterm Infants (TIPP) NCT00009646 | NICHD Neonatal Research Network | Phase 3 |
| Completed | Persistent Pulmonary Hypertension of the Newborn (PPHN) Observational Study NCT01203423 | NICHD Neonatal Research Network | — |
| Recruiting | Follow-up Visit of High Risk Infants NCT00009633 | NICHD Neonatal Research Network | — |
| Completed | Antenatal Phenobarbital to Prevent Neonatal Intracranial Hemorrhage NCT00009620 | NICHD Neonatal Research Network | Phase 3 |
| Completed | Liberal Versus Restrictive Transfusion Guidelines for Preterm Infants NCT00369005 | University of Iowa | N/A |
| Completed | Dexamethasone Therapy in VLBW Infants at Risk of CLD NCT00011362 | NICHD Neonatal Research Network | Phase 3 |
| Completed | Exosurf Neonatal and Survanta for Treatment of Respiratory Distress Syndrome NCT01203358 | NICHD Neonatal Research Network | Phase 2 / Phase 3 |
| Completed | Intravenous Immune Globulin (IVIG) to Prevent Neonatal Infection NCT01203345 | NICHD Neonatal Research Network | Phase 2 / Phase 3 |
| Recruiting | Generic Database of Very Low Birth Weight Infants NCT00063063 | NICHD Neonatal Research Network | — |