NCT01552993

Registration and Treatment of Pain During Eye Examination of Prematurity

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 5 (actual)
• Sponsor: St. Olavs Hospital · Academic / Other
• Sex: All
• Age: 31 Weeks – 37 Weeks
• Healthy volunteers: Not accepted

Summary

The aim of this study is to see if paracetamol has a pain-relieving effect during eye examination in premature infants.

Detailed description

Retinopathy of prematurity (ROP) is a feared complication of premature birth. If discovered in time, the disease can be treated, and impaired vision or blindness can be reduced. Premature infants are therefore examined regularly after birth. However, the examination is painful and stressful for the infant. Painful experiences might lead to a pathological stress response later in life and should therefore be prevented. This is a double blinded, controlled and randomized study where the infants are examined and assessed either with or without the use of paracetamol.

Conditions

• Infant, Premature
• Retinopathy

Interventions

Type	Name	Description
DRUG	paracetamol	Paracetamol mixture 20 mg/kg + pacifier and glucose
DRUG	sucrose	pacifier and sucrose

Timeline

• Start date: 2012-03-01
• Primary completion: 2012-10-01
• Completion: 2012-10-01
• First posted: 2012-03-13
• Last updated: 2016-04-22

Locations

1 site across 1 country: Norway