| Not Yet Recruiting | Outcomes From Hyperbaric Oxygen (HBO2) Treatment for Emerging Indications NCT07240649 | Jay C. Buckey Jr. | Phase 4 |
| Not Yet Recruiting | Urethral Plate Flap vs. Tunica Vaginalis Flap for Residual Severe Ventral Curvature in Hypospadias NCT07404722 | The Children's Hospital of Zhejiang University School of Medicine | N/A |
| Recruiting | Comparison of Sacral ESP Block and Dorsal Penile Nerve Block in Pediatric Hypospadias Surgery NCT07426731 | Medipol University | N/A |
| Recruiting | Fibrin-Enhanced TIP Versus Grafted TIP Urethroplasty in Distal Hypospadias NCT07319780 | National Children's Medical Center, Uzbekistan | N/A |
| Recruiting | Breaking Silence Through Story: A Narrative Medicine Intervention for Parents of Children With Urogenital Cond NCT06989593 | Sarah Schlegel | N/A |
| Not Yet Recruiting | Comparison of Caudal Block and Sacral Erector Spinae Plane Block With Dexmedetomidine in Pediatric Penile Hypo NCT07197203 | Assiut University | Phase 3 |
| Recruiting | Worldwide Yearly Screening for Hypospadias NCT06966375 | University of Wisconsin, Madison | N/A |
| Enrolling By Invitation | A Multicenter Randomized Controlled Trial Comparing Platelet-Rich Fibrin and Ventral Dartos Flap as Intermedia NCT07045545 | National Children's Medical Center, Uzbekistan | N/A |
| Recruiting | PREDICT-H Study: Prospective Research on Essential Determinants Influencing Complication Trends in Hypospadias NCT07017842 | Sidra Medicine | — |
| Completed | Randomized Trial Of Urethroplasty With Stent Versus Without Stent For Hypospadias NCT07243457 | Children's Hospital and Institute of Child Health, Multan | N/A |
| Recruiting | Improving Parental Support in Hypospadias Care NCT06832280 | University of North Carolina, Chapel Hill | N/A |
| Completed | Postoperative Pain Relief in Children: Comparing Caudal Bupivacaine Alone Versus Bupivacaine With Dexmedetomid NCT07121764 | Allama Iqbal Teaching Hospital | Phase 4 |
| Completed | Evaluation of the Method and Duration of Urinary Diversion in the Management of Distal Penile Hypospadias Foll NCT07421271 | Ain Shams University | N/A |
| Recruiting | Ultrasound Guided Sacral Erector Spinae Plane Block Versus Ultrasound Guided Caudal Block in Pediatric Undergo NCT07099560 | Tanta University | N/A |
| Completed | Comparison of Analgesic Efficacy of Sacral Erector Spinae Plane Block and Caudal Epidural Block in Pediatric P NCT07286786 | Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization | — |
| Active Not Recruiting | Effectiveness of Urethral Stent Irrigation in Preventing Surgical Site Infections in Adolescents With Hypospad NCT06520423 | Xing Liu | N/A |
| Completed | Multifidus Plane Block Versus Caudal Block for Hypospadias NCT06561269 | Ain Shams University | N/A |
| Recruiting | A Multimodal Study of the Relationship Between Exposure to Endocrine Disruptors and Occurrence of Hypospadias NCT06628375 | University Hospital, Montpellier | — |
| Completed | Can a Platelet-Rich Plasma Covering Layer Reduce Urethrocutaneous Fistula Rate After Distal Penile Hypospadias NCT07006922 | Cairo University | N/A |
| Not Yet Recruiting | Analgesia in Pediatric Hypospadias Surgeries NCT06410482 | Assiut University | N/A |
| Completed | Effect of Adding Byar's Flap to Double Dartos Coverage in TIP Urethroplasty for Distal Hypospadias: A Randomiz NCT07525570 | Javaid Afridi | N/A |
| Unknown | Modified TIP (Snodgrass) Using Interrupted Sutures in Hypospadias NCT06180018 | Assiut University | N/A |
| Recruiting | Snodgrass Versus Grafted Snodgrass Repair in Narrow Urethral Plate in Distal Penile Hypospadias NCT06405763 | Sohag University | N/A |
| Completed | Retrospective Analysis of the Neonatal Management of Patients with an Antenatal Diagnosis of Genital Developme NCT06687252 | Hospices Civils de Lyon | — |
| Active Not Recruiting | The EPigenetic Consequences in Children of Intravenous vs Volatile Anaesthesia for Surgery (EPIVA) NCT05936853 | University Hospital Southampton NHS Foundation Trust | N/A |
| Unknown | Analgesic Effects of Caudal S-ketamine for Supplementation of Ropivacaine Caudal Analgesia in Children With Hy NCT05922605 | Tao Zhang | Phase 4 |
| Recruiting | Caudal Anesthesia Versus Local Anesthesia in Hypospadias NCT06417060 | Necmi Kadıoğlu Hospital | N/A |
| Unknown | Dexmedetomidine, Ketamine and Magnesium Sulphate in Caudal Block for Hypospadias Repair NCT05837000 | Kafrelsheikh University | Phase 4 |
| Unknown | Long-term Assesment of Patients Operated for Hypospadias in Their Childhood : Urinary, Aesthetical, Sexual and NCT05319782 | Centre Hospitalier Universitaire de Besancon | N/A |
| Withdrawn | Caudal vs. Pudendal Block in Peds GU NCT05708989 | University Hospitals Cleveland Medical Center | Phase 4 |
| Unknown | Reconstructing Forked Corpus Spongiosum in Hypospadias Repair NCT04533477 | Children's Hospital of Fudan University | N/A |
| Completed | Dexmedetomidine Infusion and Surgical Pleth Index In Pediatrics NCT05727969 | Fayoum University Hospital | N/A |
| Recruiting | Is Dorsal Inlay Graft (DIG) With TIP Repair Superior to TIP Alone for Primary Hypospadias? NCT07086963 | Mohammad Daboos | N/A |
| Completed | Comparison of Analgesic Efficacy of ESP Block and Caudal Block in Patients Undergoing Hypospadias Surgery NCT05632536 | Sisli Hamidiye Etfal Training and Research Hospital | N/A |
| Unknown | Identification of Hypospadias Parameters Using Digital Photography and Artificial Intelligence NCT05569863 | Indonesia University | — |
| Completed | Comparison Of Outcome Of Different Layers in Hypospadias Surgery NCT06275646 | Children Hospital and Institute of Child Health, Lahore | N/A |
| Unknown | Efficacy of Fibrin Sealant in Hypospadias Surgery NCT05666206 | Al-Azhar University | N/A |
| Terminated | Clinical Trial to Assess the Safety and Efficacy of Investigational Product in Patients Due to Hypospadias Tre NCT05093166 | Holostem s.r.l. | Phase 1 / Phase 2 |
| Terminated | Opioid Reduction Initiative During Outpatient Pediatric Urologic Procedures Using Exparel NCT04826484 | Johns Hopkins University | Phase 3 |
| Unknown | The Optimal Urethral Coverage in Hypospadias Repair: Dartos Fascia Versus Tunica Vaginalis Flap? A Randomized NCT05123833 | Mansoura University | N/A |
| Withdrawn | Liposomal Bupivacaine vs Standard Penile Block for Hypospadias Repair NCT04479371 | University of Texas Southwestern Medical Center | Phase 1 |
| Completed | Engaging Families to Improve the Care of Patients With Hypospadias NCT05056311 | University of North Carolina, Chapel Hill | N/A |
| Unknown | The Role of "Hypospadias Objective Scoring Evaluation" (HOSE) and Uroflowmetry in Evaluation of Successful Hyp NCT05032222 | Mohammad Alaa Ezzat | — |
| Completed | USC-Exos in Corpus Spongiosum Reconstruction for Hypospadias NCT07495176 | Shanghai Children's Hospital | N/A |
| Completed | Re-operative Hypospadias Repair Using Tubularized Incised Plate Urethroplasty NCT07424768 | Tanta University | — |
| Unknown | Out Of-plane Technique Against In-plane for Caudal Block NCT04671992 | Selcuk University | N/A |
| Completed | A Prospective Registry of Patients With Congenital Penile Anomalies NCT04755803 | Seoul National University Hospital | — |
| Unknown | Assessment of Postop Hypospadias Pain NCT04423107 | University of Oklahoma | Phase 3 |
| Unknown | Selective Criteria and a Modified Technique of Applying "URAGPI" Technique for More Proximal Degree of Hypospa NCT03911635 | Assiut University | N/A |
| Withdrawn | Efficacy of Amniotic Membranes in Complex Genitourinary Reconstruction NCT03685955 | Johns Hopkins University | — |
| Completed | Long Term Follow-up for Hypospadias NCT04142632 | Hospices Civils de Lyon | — |
| Unknown | The Role of Local Long Acting Corticosteroid Injection in Hypospadias Surgery. NCT04196400 | Cairo University | EARLY_Phase 1 |
| Completed | Ultrasound-guided PNB and DPNB for Pediatric Distal Hypospadias Surgery NCT04668183 | Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization | — |
| Completed | Evaluation of Double Faced Transverse Preputial Onlay Island Flap for Hypospadias Repair in Pediatrics NCT05144659 | dr. Muhammad Abdelhafez Mahmoud, MD | N/A |
| Completed | Caudal Epidural Block and DPNB in Hypospadias NCT04215874 | Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization | — |
| Completed | Evaluation of TIP Urethroplasty With Spongioplasty-Dartosoraphy Reinforcement in Pediatric Hypospadias NCT05960123 | Al-Azhar University | N/A |
| Completed | Molecular and Structural Comparison of Hypospadic and Normal Children Prepuces NCT03838458 | Trakya University | — |
| Completed | Redo Repair in Disrupted Hypospadias NCT06187363 | Egyptian Biomedical Research Network | — |
| Completed | Interactive Perioperative Teaching Platform (IPTP) NCT03677453 | Vidya Raman | N/A |
| Not Yet Recruiting | Urothelium Tissue Engineering Using Biopsies From Transurethral Resection of Prostate NCT03698721 | Central Hospital, Nancy, France | — |
| Completed | Glans Size in Hypospadias Compared to Normal NCT03593720 | Albany Medical College | — |
| Completed | Opioid Use, Storage, and Disposal Among Pediatric Patients After Surgery NCT03575377 | Nationwide Children's Hospital | N/A |
| Completed | Modified Second Layer Repair for Distal Penile Hypospadias NCT05253456 | Ain Shams University | Phase 2 |
| Enrolling By Invitation | Genetics of Differences of Sex Development and Hypospadias NCT03102554 | Boston Children's Hospital | N/A |
| Completed | Penile Ischemia for Hypospadias Repair and The Patients and Surgeons Reported Outcomes NCT04239066 | Mansoura University | N/A |
| Completed | Urethrocutaneous Fistula Rate After Double Dartos and Single Dartos Tubularized Incised Plate Urethroplasty NCT04699318 | King Edward Medical University | N/A |
| Completed | Does Caudal Block Increase the Incidence of Urethrocutaneous Fistula Formation Following Hypospadias Repair in NCT02861950 | University of Colorado, Denver | Phase 4 |
| Completed | Isoamyl 2-Cyanoacrylate in the Urethro-cutaneous Fistula Repair NCT04876976 | Ain Shams University | Phase 2 / Phase 3 |
| Completed | Effect of Intravenous Dexamethasone With Pudendal Nerve Block on Postoperative Pain in Pediatric Hypospadias R NCT03902249 | Dr Sonia ben khalifa (PhD) | Phase 4 |
| Completed | Effect of Caudal and Penile Block on Hypospadias Repair Complications NCT02851290 | Baylor College of Medicine | N/A |
| Unknown | Caudal vs Local Anesthesia in Hypospadias NCT02512887 | McMaster University | N/A |
| Completed | Effects of Dexmedetomidine as Adjunct to Pudendal Block for Pediatric Penile Surgery NCT02848157 | Yonsei University | Phase 4 |
| Unknown | Foreskin Graft Tubularized Incised Plate Urethroplasty vs Tubularized Incised Plate for Primary Hypospadias (F NCT02497963 | Hospital Infantil de Mexico Federico Gomez | N/A |
| Completed | Antibiotic Use in Distal Hypospadias Repair NCT03275519 | Arkansas Children's Hospital Research Institute | N/A |
| Completed | Hypospadias and Exome: Identification of New Genes for Familial Hypospadias NCT02495090 | University Hospital, Montpellier | N/A |
| Completed | Effectiveness of Caudal Epidural Block on Intraoperative Blood Loss During Hypospadias Repair NCT02752308 | Isfahan University of Medical Sciences | Phase 2 / Phase 3 |
| Completed | The Effect of Caudal Block on the Postoperative Complications in Pediatric Patients After Hypospadias Repair NCT02164682 | Yonsei University | — |
| Terminated | Effect of Steroids on Post-Operative Complications Following Proximal Hypospadias Repair NCT02162810 | Francis Schneck | N/A |
| Completed | Antibiotic Use Following Distal and Mid-shaft Hypospadias Repair NCT02593903 | Medical College of Wisconsin | N/A |
| Active Not Recruiting | Prophylactic Antibiotics or Placebo After Hypospadias Repair NCT02096159 | Ann & Robert H Lurie Children's Hospital of Chicago | N/A |
| Completed | Visual Guidelines and Tutoring in Pediatric Urological Surgery NCT02040389 | Shaare Zedek Medical Center | N/A |
| Completed | Decision Support for Parents Receiving Information About Child's Rare Disease NCT01875640 | University of Michigan | — |
| Withdrawn | The Change of the Detrusor Thickness After Hypospadias Repair - Comparison With the Normal Control Group NCT01762007 | Yonsei University | — |
| Completed | Long Term Outcome of Hypospadias Repair NCT02103712 | The Leeds Teaching Hospitals NHS Trust | — |
| Completed | Local Oestrogen Versus Placebo as Preoperative Treatment in Patients With Severe Hypospadias: Effects on Post- NCT01370798 | Hospices Civils de Lyon | Phase 3 |
| Completed | Influence of Pesticide Exposure on the Occurrence of Hypospadias in Newborns in Picardie NCT02805491 | Centre Hospitalier Universitaire, Amiens | — |