NCT04196400

The Role of Local Long Acting Corticosteroid Injection in Hypospadias Surgery.

Prospective Comparative Trial to Assess the Role of Local Long Acting Steroid Injection After Hypospadias Surgery in Decreasing Complications and Preserving Better Cosmesis

• Status: Unknown
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: Male
• Age: 6 Months
• Healthy volunteers: Not accepted

Summary

Post-operative tissue oedema is one of the main causes of failure of hypospadias repair. Severe oedema may disrupt the suture line, invite infection and result in repair failure. Thus, we suggested that local injection of corticosteroids in just below coronal sulcus into dartos and buck's fascia may limit this oedema thus improving the outcome of hypospadias repair.

Detailed description

This is a prospective comparative trial : comparing the use of local steroids injection to reduce tissue edema after hypospadias and to preserve the final cosmesis after tissue repair. The patients will be divided into 2 groups(each group 20 patients): one group will be injected steroids just after hypospadias surgery while the other will not. The short and long term outcomes between both groups will be compared.

Conditions

• Hypospadias

Interventions

Type	Name	Description
DRUG	steroid betamethasone	The steroid is injected using insulin needle in the subcutaneous tissue after finishing the repair

Timeline

• Start date: 2019-12-01
• Primary completion: 2020-12-31
• Completion: 2021-03-01
• First posted: 2019-12-12
• Last updated: 2019-12-12

Locations

1 site across 1 country: Egypt