NCT02103712

Long Term Outcome of Hypospadias Repair

Long Term Outcome of Hypospadias Repair: A Comparative Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 170 (actual)
• Sponsor: The Leeds Teaching Hospitals NHS Trust · Academic / Other
• Sex: Male
• Age: 3 Years – 17 Years
• Healthy volunteers: Not accepted

Summary

Hypospadias is a common congenital abnormality of the penis which affects approximately 1 boy in 250. The opening of the urethra is located on the undersurface of the penis rather than the tip,the foreskin is deficient and there is curvature of the penile shaft in more severe cases. Although the most commonly practised corrective operation ( TIP procedure) gives generally good results, recently published evidence points to a possible long term risk of stenosis ( narrowing of the reconstructed urethra). This comparative study will combine clinical assessment with non invasive measurements of urinary flow to assess the functional outcome of a large series of patients who have undergone hypospadias surgery . The study is primarily designed to answer this question : does a modification of the standard operation which incorporates a skin graft into the reconstructed urethra lead to improved urinary flow and a decreased risk of stenosis? This has not been previously studied . The findings of our study could make an important contribution to improvements in the surgical treatment of boys born with hypospadias.

Conditions

• Hypospadias

Interventions

Type	Name	Description
OTHER	Qualitative

Timeline

• Start date: 2012-10-01
• Primary completion: 2013-09-30
• Completion: 2013-09-30
• First posted: 2014-04-04
• Last updated: 2019-08-19

Locations

1 site across 1 country: United Kingdom