NCT05666206

Efficacy of Fibrin Sealant in Hypospadias Surgery

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Al-Azhar University · Academic / Other
• Sex: Male
• Age: 3 Months – 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of the study was to evaluate if application of a fibrin sealant over the urethroplasty suture line for waterproofing instead of a dartos vascularized pedicled flap to reduce complications and improve the outcome in hypospadias repair.

Detailed description

Many procedures have been tried for the sake of proper management of hypospadias and reducing the complications. Of them, tabularized incised plate (TIP) is one of the most convenient technique, which became the most common procedure for hypospadias repair (Elsayem et al., 2022). Although many surgical modifications and techniques have been prescribed to minimize post-operative complications and improve outcomes, a high percentage of complications still occurs. Urethrocutaneous fistulae are the most common post-operative complication (10%-40%) after hypospadias surgery; other complications being skin flap related complications such as flap necrosis, suture line breakdown, ascent of the testis and penile torsion (Shenoy et al.,2021). In this thesis a secondary preputial dartos flap will be performed in all cases and we will evaluate the value of usage of fibrin glue on the 1ry suture line .

Conditions

• Hypospadias

Interventions

Type	Name	Description
PROCEDURE	fibrin sealant in hypospadias	fibrin sealant will be used over the suture line

Timeline

• Start date: 2022-01-01
• Primary completion: 2024-11-01
• Completion: 2024-12-01
• First posted: 2022-12-27
• Last updated: 2024-02-13

Locations

1 site across 1 country: Egypt