| Not Yet Recruiting | Long-term Effects of Family WISH Program for Adolescents With Congenital Heart Disease NCT06719323 | Chi-Wen Chen | N/A |
| Not Yet Recruiting | Study on the Safety and Effectiveness of a Biodegradable Patent Foramen Ovale Occluder System NCT07300358 | Shanghai Lingsi Medical Technology Co., Ltd. | N/A |
| Recruiting | HeartGPS: A Study Exploring the Effects of a Psychological Intervention for Parents and Their Babies After Pre NCT06175104 | Children's Hospital Medical Center, Cincinnati | N/A |
| Not Yet Recruiting | Development and Improvement of Home Rehabilitation Scheme for Preschool Children With Congenital Heart Disease NCT07055334 | Wei XIA, PhD | — |
| Recruiting | High-Flow Nasal Cannula vs. NIV After Extubation in Children Undergoing Heart Surgery NCT07059689 | Indonesia University | N/A |
| Not Yet Recruiting | Effects of Rehabilitation Programme on Respiratory Function in Patients with Acquired and Intervened Congenita NCT06185140 | University of Salamanca | N/A |
| Completed | Tuning in to Kids: An Online, Group Program Tailored for Parents of Children With Congenital Heart Disease NCT06609707 | Children's Hospital Medical Center, Cincinnati | N/A |
| Terminated | Advancing the Science of Pediatric Interstage Home Monitoring NCT06547268 | Ann & Robert H Lurie Children's Hospital of Chicago | — |
| Unknown | The Effects of the Otago Exercise Program NCT06172790 | Istanbul University - Cerrahpasa | N/A |
| Terminated | Effectiveness of CRD-4730 in Participants With Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) NCT06005428 | Cardurion Pharmaceuticals, Inc. | Phase 2 |
| Enrolling By Invitation | CHAMP App Cardiac Study and Repository NCT06034392 | Lori Erickson | — |
| Recruiting | Congenital Heart Disease Physical Activity Lifestyle Study V.2 NCT06003023 | Jamie Jackson | N/A |
| Completed | Study on the Construction and Application of Breastfeeding Behavior Intervention Program for Mothers of Infant NCT05961540 | Children's Hospital of Fudan University | N/A |
| Completed | The Effects of Different Prone Positioning Angles on Cardiopulmonary Function in Children After Congenital Hea NCT07323979 | Guangdong Provincial People's Hospital | N/A |
| Recruiting | Mind the Heart - Mental Health in Children and Adolescents With Congenital Heart Defects NCT05709470 | Rigshospitalet, Denmark | — |
| Unknown | Accelerated Aging in Newborns and Adults With Congenital Heart Disease NCT05667870 | KU Leuven | — |
| Not Yet Recruiting | DEX vs SEVO in Congenital Heart Surgery NCT05369949 | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | Phase 4 |
| Active Not Recruiting | Genetics of Ventriculo-arterial Discordance NCT05330338 | Nantes University Hospital | N/A |
| Completed | EF Intervention in Children With Severe Congenital Heart Disease NCT05198583 | University Children's Hospital, Zurich | N/A |
| Unknown | Liver Disease, Myocardial Fibrosis and Collaterals in the Adult Fontan Patient a Metabolomics and Proteomics A NCT04764305 | Medical University Innsbruck | — |
| Unknown | Use of the Cardioprotectant Dexrazoxane During Congenital Heart Surgery NCT04997291 | University of Texas at Austin | Phase 1 |
| Active Not Recruiting | Safety and Efficacy Study of reSept ASD Occluder for Treating Secundum ASD NCT04591392 | atHeart Medical | N/A |
| Completed | Congenital Heart Anomaly Risk in Maternal Enteroviral Infection and Diabetes NCT04769167 | Washington University School of Medicine | N/A |
| Unknown | Evaluation of the Diagnostic Performance of Specialized Fetal Cardiac Ultrasound in the CPDPN - Arc Alpin Netw NCT04866537 | University Hospital, Grenoble | — |
| Unknown | Impact of NAVA Ventilation on Brain Oxygenation and Perfusion in Children With Congenital Heart Disease NCT04581668 | St. Justine's Hospital | N/A |
| Withdrawn | Xeltis Pulmonary Valved Conduit Safety and Performance Study NCT03405636 | Xeltis | N/A |
| Recruiting | Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular Grafts NCT04467671 | Nationwide Children's Hospital | Phase 2 |
| Completed | Transcatheter Versus Surgical Closure of Ventricular Septal Defect: A Comparative Study NCT05306483 | Ain Shams University | N/A |
| Unknown | Capnography Monitoring in Ventilated Children NCT04354220 | Vincenzo Cannizzaro | — |
| Withdrawn | Rejuvenated, Washed Packed Red Blood Cells in Pediatric Cardiac Surgery NCT02485366 | Duke University | Phase 4 |
| Enrolling By Invitation | Global Utilization And Registry Database for Improved heArt preservatioN NCT04141605 | Paragonix Technologies | — |
| Completed | The Use of Music for Neonates Post-Cardiac Surgery NCT03925584 | Boston Children's Hospital | N/A |
| Unknown | Remotely Monitored and Coached Cardiac Rehabilitation Northern Sweden NCT03479957 | Umeå University | N/A |
| Recruiting | European Prospective Registry on Anomalous Aortic Origin of the Coronary Arteries NCT06089902 | University of Padova | — |
| Unknown | Drug-induced Repolarization ECG Changes NCT03642405 | Copenhagen University Hospital at Herlev | — |
| Completed | Rehabilitation of Adolescents and Young Adults With Congenital Heart Diseases NCT03690518 | University Hospital, Montpellier | N/A |
| Active Not Recruiting | Evaluation of the GORE PV1 Device in Patients With Pulmonary Valve Dysfunction NCT03441971 | W.L.Gore & Associates | N/A |
| Completed | Safety of Autologous Cord Blood Cells in HLHS Patients During Norwood Heart Surgery NCT03431480 | Murdoch Childrens Research Institute | Phase 1 |
| Unknown | Physical Capacity and Activity in Children With Congenital Heart Disease NCT03275844 | Rodrigo Torres | — |
| Completed | Effect of Phosphodiesterase-5 Inhibition With Tadalafil on SystEmic Right VEntricular Size and Function NCT03049540 | Insel Gruppe AG, University Hospital Bern | Phase 3 |
| Completed | Livet Skal Leves (A Life to Live) NCT03957512 | Oslo University Hospital | — |
| Completed | COMPASSION XT PAS - Post-approval Study of the SAPIEN XT THV in Patients With Pulmonary Valve Dysfunction NCT02987387 | Edwards Lifesciences | — |
| Completed | Quantification of Cerebral Perfusion by Contrast-enhanced Ultrasound During Neonatal Heart Surgery NCT03215628 | University of Erlangen-Nürnberg Medical School | N/A |
| Unknown | Impact of Congenital Heart Disease on Neurodevelopmental Outcome NCT03871881 | University of Aarhus | — |
| Completed | CTICU Pacifier Activated Music Player and Mother's Voice NCT03035552 | Nationwide Children's Hospital | N/A |
| Completed | The Fontan Education Study: A Randomized Control Trial NCT02831790 | University of Alberta | N/A |
| Unknown | The Management of Systemic-Pulmonary Collateral Blood Flow in Cyanotic Children During Cardiopulmonary Bypass NCT02358382 | Great Ormond Street Hospital for Children NHS Foundation Trust | N/A |
| Unknown | Right Lateral Positioning of Postoperative Pediatric Cardiac Surgery NCT02622152 | Assiut University | N/A |
| Completed | Lactate Levels During Cardiopulmonary Bypass in Pediatric Patients NCT02618707 | Assiut University | — |
| Recruiting | Genes Associated With Development of Pulmonary Arterial Hypertension in Patients With Congenital Shunt Lesions NCT02691689 | Universitaire Ziekenhuizen KU Leuven | N/A |
| Completed | Colloid Osmotic Pressure in Patients With Fontan Circulation NCT02443662 | Oslo University Hospital | — |
| Completed | Motor Development of Children That Have Surgery as Newborns for Complex Congenital Heart Disease NCT02781545 | Wake Forest University Health Sciences | — |
| Completed | The CHAPTER III Study of Young Adolescents NCT02374892 | University of Alberta | N/A |
| Completed | Parent Communication for Feeding an Infant With a Heart Defect NCT04452201 | University of Wisconsin, Madison | N/A |
| Completed | Fluid Balance in Children Undergoing Fontan Surgery NCT02306057 | Oslo University Hospital | — |
| Terminated | Use of the Cardioprotectant Dexrazoxane During Congenital Heart Surgery: Proposal for Pilot Investigation NCT02519335 | Medical City Children's Hospital | Phase 1 |
| Completed | Micronutrients in Children in Critical Care With Cardiac Conditions NCT02409706 | NHS Greater Glasgow and Clyde | — |
| Completed | Safety and Performance of a Vascular Patch in Pediatric Patients Undergoing Bidirectional Cava-pulmonary Anast NCT02377700 | Xeltis | N/A |
| Unknown | Right Ventricular Dysfunction in Tetralogy of Fallot: Inhibition of the Renin-angiotensin-aldosterone System NCT02010905 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | Phase 2 |
| Completed | Safety and Performance of the COR-VG-001 Conduit in Pediatric Patients for Extracardiac Total Cavopulmonary Co NCT02377674 | Xeltis | N/A |
| Completed | Prevention of Vitamin D Deficiency Following Pediatric CHD Surgery: a Phase II Dose Evaluation Randomized Cont NCT01838447 | Children's Hospital of Eastern Ontario | Phase 2 |
| Completed | Feasibility Study of the Adult Congenital Heart Disease-Coping and Resilience (ACHD-CARE) Trial NCT01881893 | University Health Network, Toronto | N/A |
| Completed | Patient-Reported Outcomes in Adults With Congenital Heart Disease NCT02150603 | Philip Moons | — |
| Completed | Impact of Early Intervention on Maternal Stress in Mothers of Fetuses Diagnosed With Single Ventricle Physiolo NCT02462434 | University of Michigan | N/A |
| Completed | Cardiopulmonary Rehabilitation for Adolescents and Adults With Congenital Heart Disease NCT01822769 | Boston Children's Hospital | N/A |
| Completed | Fluid Balance During Closure of Atrial Septal Defect NCT01757743 | Oslo University Hospital | — |
| Completed | Congenital Heart Defects and NIRS NCT03411512 | Petja Fister, MD, PhD | — |
| Completed | Pre-operative Cerebral Oxygenation in Neonates With Congenital Heart Disease NCT01679275 | Universitaire Ziekenhuizen KU Leuven | — |
| Completed | Leuven Growing Into Deficit Follow-up Study NCT01632813 | KU Leuven | — |
| Completed | Feasibility Study Over the NAVA Mode in Noninvasive Ventilation After Cardiac Surgery in Infants. NCT01570933 | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | Phase 4 |
| Completed | NIRS Guidance Trail in Children's Heart Surgery NCT02157597 | Children's Hospital Medical Center, Cincinnati | N/A |
| Completed | Neuroprotective Effects of Remote Ischemic Preconditioning (RIPC) During Infant Cardiac Surgery NCT01835392 | Nemours Children's Clinic | N/A |
| Completed | Colloid Osmotic Pressure During Heart Surgery in Children NCT01397526 | Oslo University Hospital | — |
| Unknown | InterSEPT: In-Tunnel SeptRx European PFO Trial NCT01385670 | SeptRx, Inc. | N/A |
| Terminated | Rehabilitation in Patients With Congenital Heart Disease NCT01463800 | University Hospital, Basel, Switzerland | N/A |
| Completed | Study Using Citrate to Replace Heparin in Babies Requiring Extracorporeal Membrane Oxygenation (ECMO) NCT00968565 | Vanderbilt University | EARLY_Phase 1 |
| Completed | Mixed Venous Oxygen Saturation From Central Venous Line, Venous Side of Heart Lung Machine and the Pulmonary A NCT02498626 | Assiut University | — |
| Completed | Long Term Safety of Clopidogrel in Neonates/Infants With Systemic to Pulmonary Artery Shunt Palliation NCT00833703 | Sanofi | Phase 3 |
| Completed | Myocardial Protection With Adenosine Preconditioning NCT00881686 | Xijing Hospital | Phase 1 / Phase 2 |
| Terminated | Effects of Perioperative Nesiritide or Milrinone Infusion on Recovery From Fontan Surgery NCT00543309 | John M Costello | Phase 2 |
| Completed | Genes Causing Ebstein's Anomaly NCT00497705 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Unknown | Pediatric Exercise With Congenital Heart Defects (Kinderturnen Mit Angeborenem Herzfehler) NCT00436098 | Deutsches Herzzentrum Muenchen | N/A |
| Completed | Efficacy And Safety Of Clopidogrel In Neonates /Infants With Systemic To Pulmonary Artery Shunt Palliation NCT00396877 | Sanofi | Phase 3 |
| Completed | SPECS: Safe Pediatric Euglycemia in Cardiac Surgery NCT00443599 | Boston Children's Hospital | N/A |
| Completed | Ontario Multidetector Computed Tomographic (MDCT) Coronary Angiography Study (OMCAS) NCT00371891 | St. Joseph's Healthcare Hamilton | Phase 4 |
| Completed | Physical Activity in Fontan Patients NCT00363363 | The Hospital for Sick Children | Phase 3 |
| Completed | Genetic and Nutritional Causes of Heart Birth Defects NCT00368732 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery NCT00335244 | Asklepion Pharmaceuticals, LLC | Phase 3 |
| Terminated | Nesiritide Use Following Cardiac Surgery in Infants NCT00281671 | Boston Children's Hospital | Phase 1 / Phase 2 |
| Completed | Comparison of Two Types of Shunts in Infants With Single Ventricle Defect Undergoing Staged Reconstruction--Pe NCT00115934 | Carelon Research | N/A |
| Terminated | Angiotensin Converting Enzyme Inhibition in Children With Mitral Regurgitation NCT00113698 | University of Utah | Phase 3 |
| Completed | Citrulline for Children Undergoing Cardiopulmonary Bypass Surgery NCT00201214 | Vanderbilt University | Phase 1 / Phase 2 |
| Completed | Trial of Angiotensin Converting Enzyme Inhibition in Infants With Single Ventricle--Pediatric Heart Network NCT00113087 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 3 |
| Completed | Hypertonic Saline Dextran in Pediatric Cardiac Surgery NCT00199771 | Oslo University Hospital | Phase 2 |
| Completed | Study of Triostat in Infants During Heart Surgery NCT00027417 | Michael Portman | Phase 3 |
| Completed | Comparison of Hematocrit Levels in Infant Heart Surgery NCT00006183 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 3 |
| Completed | Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults With Repaired NCT00004361 | National Center for Research Resources (NCRR) | — |
| Completed | Liothyronine in Children With Single Ventricle Congenital Cardiac Malformations Undergoing the Fontan Procedur NCT00004828 | FDA Office of Orphan Products Development | Phase 1 |
| Unknown | Long-term Survival After Single-ventricle Palliation NCT03356574 | Karolinska University Hospital | — |
| Completed | Body Water Content in Cyanotic Congenital Heart Disease NCT00000107 | National Center for Research Resources (NCRR) | — |