Trials / Completed
CompletedNCT01757743
Fluid Balance During Closure of Atrial Septal Defect
Protein Distribution and Colloid Osmotic Pressure in Children With Volume and Pressure Loading Due to Congenital Heart Defects
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 41 (actual)
- Sponsor
- Oslo University Hospital · Academic / Other
- Sex
- All
- Age
- 6 Months – 10 Years
- Healthy volunteers
- Not accepted
Summary
This project will evaluate fluid balance and oedema formation in children with the same congenital heart disease (Atrial Septal Defect) who will either go through heart surgery with the use of Cardio Pulmonary Bypass and hypothermia or through interventional catheterization. The investigators will measure interstitial colloid osmotic pressure, distribution of proteins and cytokines. The study hypothesis is that "Oedema developed during heart surgery is caused by reduced colloid osmotic pressure gradient through the capillary membrane".
Conditions
Timeline
- Start date
- 2013-02-01
- Primary completion
- 2017-01-01
- Completion
- 2017-01-01
- First posted
- 2012-12-31
- Last updated
- 2017-04-11
Locations
1 site across 1 country: Norway
Source: ClinicalTrials.gov record NCT01757743. Inclusion in this directory is not an endorsement.