| Recruiting | Immunomodulatory Effects of Dexamethasone, Tocilizumab and Anakinra During Experimental Human Endotoxemia NCT06624436 | Radboud University Medical Center | Phase 4 |
| Recruiting | Different Dietary Patterns NCT06147440 | University of Vienna | N/A |
| Completed | Elevated Levels of Antibodies to Endotoxin Core in Hemodialysis Patients With Peripheral Artery Disease NCT05752968 | Tungs' Taichung Metroharbour Hospital | — |
| Completed | Dietary Intervention to Reduce Metabolic Endotoxemia NCT05776329 | Centro de Investigación en Alimentación y Desarrollo A.C. | N/A |
| Unknown | The Relations Among Endotoxin, Inflammatory Cytokines, Cognitive Markers and Brain MRI Changes in Subjects Wit NCT06203015 | Lithuanian University of Health Sciences | — |
| Active Not Recruiting | Assessing Gut Microbiota Mediated Health Outcomes of Whole Wheat and Its Major Bioactive Components NCT05318183 | Ohio State University | N/A |
| Terminated | Rifaximin in Cirrhosis: Effects on Endotoxin and Haemostatic Indexes NCT06630572 | University of Roma La Sapienza | Phase 4 |
| Completed | Effects of Non-calorie Sweeteners, Mono- and Disaccharides on Intestinal Barrier Function NCT04788680 | University of Vienna | N/A |
| Completed | Demonstration of the Prebiotic-like Effects of Camu-camu Consumption Against Obesity-related Disorders in Huma NCT04130321 | Laval University | N/A |
| Active Not Recruiting | Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Labe NCT03901807 | Spectral Diagnostics (US) Inc. | N/A |
| Completed | Effects of Maple Syrup on Gut Microbiota Diversity and Metabolic Syndrome NCT04117802 | Laval University | N/A |
| Completed | Gut-level Antiinflammatory Activities of Green Tea in Metabolic Syndrome NCT03973996 | Ohio State University | N/A |
| Completed | Anabolic Potential of 3-hydroxybutyrate (3-OHB) and Whey Protein in a Human Catabolic Inflammatory Disease Mod NCT04064268 | University of Aarhus | N/A |
| Completed | Echocardiographic Changes After 3-hydroxy Butyrate+Whey Intake NCT04037722 | University of Aarhus | N/A |
| Completed | Gastro-intestinal and Hormonal Responses to Systemic Inflammatory Disease NCT04056286 | University of Aarhus | N/A |
| Completed | Determining the Fingerprint of Endotoxin Tolerance NCT06801873 | Radboud University Medical Center | N/A |
| Completed | Foodprint 1.0: Physiological Acute Responses After Consumption of Confectionary Products NCT03972878 | University of Parma | N/A |
| Completed | Effect of Cranberry and Agaves Extract on Microbiota and Intestinal Health NCT03800277 | Laval University | N/A |
| Completed | Effects of Cranberry Powder Supplements on Gut Microbiota Diversity and Metabolic Syndrome NCT03754504 | Laval University | N/A |
| Completed | Dietary Green Tea Confection For Resolving Gut Permeability-Induced Metabolic Endotoxemia In Obese Adults NCT03413735 | Ohio State University | N/A |
| Completed | Cardiometabolic Benefits of Potatoes Mediated Along the Gut-Vessel Axis in Adults With Metabolic Syndrome NCT03624569 | Ohio State University | N/A |
| Completed | Cereals and Intestinal Function NCT04019457 | University of Vienna | N/A |
| Completed | Whey vs Casein to Combat Post-inflammatory Protein and Muscle Waste in Acute Disease NCT03319550 | University of Aarhus | N/A |
| Completed | A New Model of Acute Febrile Disease NCT03158363 | University of Aarhus | N/A |
| Completed | Defibrotide in the Human Endotoxemia Model --- an Exploratory Trial Investigating the Effects and the Mechanis NCT02876601 | Bernd Jilma | Phase 4 |
| Completed | The Effects of Acetylsalicylic Acid on Immunoparalysis Following Human Endotoxemia NCT02922673 | Radboud University Medical Center | N/A |
| Completed | Effect of Monosaccharides on Intestinal Barrier Function NCT03482284 | Prof. Dr. Ina Bergheim | N/A |
| Completed | Effects of Cold Exposure and Breathing Techniques on Immune Response NCT03240497 | Radboud University Medical Center | N/A |
| Completed | Effects of Vasopressors on Immune Response NCT02675868 | Radboud University Medical Center | Phase 4 |
| Completed | Ticagrelor in Human Endotoxemia Response to Human Endotoxemia NCT02612480 | Radboud University Medical Center | N/A |
| Completed | PK/PD of EA-230 During Endotoxemia NCT02629874 | Radboud University Medical Center | Phase 1 |
| Completed | The Role of the Gut Microbiota in the Systemic Immune Response During Human Endotoxemia NCT02127749 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Completed | The Role of Dietary Fat on Postprandial Endotoxemia in Healthy Adults NCT02521779 | Iowa State University | N/A |
| Completed | In Vivo Effects of C1-esterase Inhibitor on the Innate Immune Response During Human Endotoxemia - VECTOR II NCT01766414 | Radboud University Medical Center | Phase 3 |
| Completed | Probiotic Sport Study NCT01474629 | Green Beat | N/A |
| Completed | The Effects of Immunostimulation With GM-CSF or IFN-y on Immunoparalysis Following Human Endotoxemia NCT01374711 | Radboud University Medical Center | N/A |
| Completed | Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Septic Shock NCT01046669 | Spectral Diagnostics (US) Inc. | N/A |
| Completed | The Effects of Oral Dipyridamole Treatment on the Innate Immune Response During Human Endotoxemia NCT01091571 | Radboud University Medical Center | Phase 4 |
| Completed | Anti-inflammatory Effects of Enriched Enteral Nutrition During Human Experimental Endotoxemia NCT01100996 | Radboud University Medical Center | N/A |
| Completed | The Effects of Atazanavir-induced Hyperbilirubinemia During Human Endotoxemia NCT00916448 | Radboud University Medical Center | N/A |
| Completed | In Vivo Effects of C1-esterase Inhibitor on the Innate Immune Response During Human Endotoxemia NCT00785018 | Radboud University Medical Center | N/A |
| Completed | Anti-inflammatory Effects of GTS-21 After LPS NCT00783068 | Radboud University Medical Center | N/A |
| Completed | A Possible Therapeutic Role for Adenosine During Inflammation NCT00513110 | Radboud University Medical Center | Phase 1 |
| Completed | Study of Gene Activity in Fat and Muscle in Diabetics and Healthy Controls NCT00412906 | Rigshospitalet, Denmark | N/A |
| Unknown | Study of Renal Blood Flow During Human Endotoxemia NCT00413465 | Rigshospitalet, Denmark | N/A |
| Unknown | Type 2 Diabetes and the Effect of Probiotics NCT00413348 | Rigshospitalet, Denmark | N/A |
| Completed | Cerebral Blood Flow and Metabolism During Hypoxia and Endotoxemia NCT00332267 | Rigshospitalet, Denmark | N/A |
| Completed | Anti-Inflammatory Effect of Statins in the Human Endotoxin Model NCT00309374 | Medical University of Vienna | Phase 1 |
| Completed | Ethnic Differences in the Inflammatory Response in Systemic Inflammation NCT00284869 | Medical University of Vienna | Phase 1 |
| Completed | Pathophysiology and Clinical Relevance of Endotoxin Tolerance in Humans NCT00246714 | Radboud University Medical Center | Phase 1 |
| Completed | Effect of Selective iNOS Inhibition During Human Endotoxemia NCT00184990 | Radboud University Medical Center | Phase 1 |
| Unknown | Low-Dose Endotoxemia and the Acute Phase Response NCT00197899 | Herlev Hospital | N/A |
| Completed | Blockade of Vascular Potassium Channels During Human Endotoxemia NCT00185003 | Radboud University Medical Center | Phase 1 |
| Temporarily Not Available | Open-label Evaluation of Polymyxin B Hemoperfusion for Septic Shock NCT02825329 | Spectral Diagnostics (US) Inc. | — |
| No Longer Available | Evaluating the Use of Polymyxin B Cartridge Hemoperfusion for Patients With Septic Shock and COVID 19 NCT04352985 | Spectral Diagnostics (US) Inc. | — |