| Not Yet Recruiting | Imbalances of Regional Pulmonary Ventilation in Patients With Post-acute-COVID-19 NCT05238623 | Jan-Christoph Lewejohann | — |
| Recruiting | Cardiovascular Disease Progression in Survivors of Community Acquired Pneumonia and Lung Infection by Covid-19 NCT06601998 | Hellenic Institute for the Study of Sepsis | — |
| Withdrawn | Mesenchymal Stromal Cells for COVID-19 and Viral Pneumonias NCT05286255 | Medical University of South Carolina | Phase 1 |
| Recruiting | AI-based System for Assessing Suspected Viral Pneumonia Related Lung Changes NCT06501599 | Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department | — |
| Unknown | Efficacy of Bailing Capsule on Pulmonary Fibrosis After COVID-19 NCT05890573 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Unknown | NAC for Attenuation of COVID-19 Symptomatology NCT05074121 | Cambridge Health Alliance | Phase 2 |
| Recruiting | Passive Detection- SARS-CoV-2 (COVID-19) A&M Breathalyzer (PROTECT Kiosk) for Operational Medicine NCT06402318 | The Geneva Foundation | — |
| Completed | CPAP Therapy Through a Helmet or a Full Face Mask in Patients With Acute Hypoxemic Respiratory Failure: Cross- NCT06113432 | I.M. Sechenov First Moscow State Medical University | N/A |
| Unknown | Characteristics of Blood Glucose Variability in Patients With Type 2 Diabetes Mellitus and COVID-19 NCT06156137 | Qilu Hospital of Shandong University | — |
| Active Not Recruiting | SARS-CoV-2/COVID-19 Study of Next Generation Non-Invasive Passive Detection Technologies NCT05765396 | The Geneva Foundation | — |
| Unknown | Factors Associated With Failure of HFNO in COVID-19 ICU Patients NCT05798234 | Central Hospital, Nancy, France | — |
| Recruiting | Corona Virus Disease 2019 Cohort Study NCT06927622 | Shandong University | — |
| Unknown | Efficacy of Lianhua Qingwen in Treating Patients Infected With the Omicron Variant of the COVID-19 NCT05778318 | Qianfoshan Hospital | — |
| Completed | COVID-19 Breakthrough Infection in Fully Vaccinated People and in People Who Received a Booster Dose NCT05392075 | Methodist Health System | — |
| Unknown | Efficacy and Safety of Jaktinib in Patients With COVID-19 Pneumonia. NCT05672888 | First Affiliated Hospital of Zhejiang University | Phase 2 |
| Unknown | The Difference Between Non-invasive High-frequency Oscillatory Ventilation and Non-invasive Continuous Airway NCT05706467 | Guangzhou Institute of Respiratory Disease | N/A |
| Unknown | Pharmacokinetics and Safety of GST-HG171 Tablets in Subjects With Impaired and Normal Renal Function NCT06106126 | Fujian Akeylink Biotechnology Co., Ltd. | N/A |
| Unknown | A Clinical Study on Safety and Effectiveness of Mesenchymal Stem Cell Exosomes for the Treatment of COVID-19. NCT05787288 | First Affiliated Hospital of Wenzhou Medical University | EARLY_Phase 1 |
| Unknown | Efficacy of Megadose Vitamin C in Severe and Critical Ill COVID-19 Patients. NCT05694975 | Zhujiang Hospital | Phase 2 / Phase 3 |
| Unknown | Bevacizumab in Patients With Severe Covid-19 NCT04305106 | Qilu Hospital of Shandong University | Phase 3 |
| Unknown | UC-MSCs in the Treatment of Severe and Critical COVID-19 Patients With Refractory Hypoxia NCT05689008 | Shanghai East Hospital | Phase 3 |
| Unknown | UC-MSCs in the Treatment of Severe and Critical COVID-19 Patients NCT05682586 | Shanghai East Hospital | Phase 3 |
| Completed | A Study to Evaluate the Relative Bioavailability of STI-1558 and the Effect of Itraconazole and Rifampin on th NCT05685719 | Zhejiang ACEA Pharmaceutical Co. Ltd. | Phase 1 |
| Unknown | Traditional Chinese Medicine or Low-dose Dexamethasone in COVID-19 Pneumonia NCT05798195 | China-Japan Friendship Hospital | N/A |
| Completed | Jing Si Herbal Tea for Long-Coronavirus Disease(COVID) Gut-brain Interaction NCT05668104 | Buddhist Tzu Chi General Hospital | N/A |
| Unknown | Low-Dose Radiation Therapy for Severe COVID-19 Pneumonia NCT05694962 | Jiangsu Cancer Institute & Hospital | Phase 2 |
| Completed | Study of GST-HG171/Ritonavir Compared With Placebo in Patients With Mild to Moderate COVID-19 NCT05656443 | Fujian Akeylink Biotechnology Co., Ltd. | Phase 2 / Phase 3 |
| Completed | Pharmacokinetics and Safety of GST-HG171 Tablets in Subjects With Impaired and Normal Liver Function NCT06106113 | Fujian Akeylink Biotechnology Co., Ltd. | Phase 1 |
| Completed | Pirfenidone in Adult Hospitalized Patients With COVID-19 NCT05713292 | Capital Medical University | Phase 3 |
| Recruiting | Phase 2/Phase 3 Study To Evaluate The Efficacy And Safety Of Ramatroban Along With The Standard Of Care In Sub NCT05706454 | KARE Biosciences | Phase 2 / Phase 3 |
| Withdrawn | Respiratory COVID-19: A Randomized, Sham-Controlled Study NCT05166915 | Aytu BioPharma, Inc. | N/A |
| Completed | Investigation of Efficacy and Safety of Electrical Signal Therapy Provided by Dr Biolyse® Device in COVID-19 D NCT06113757 | AVB Biotechnology | N/A |
| Completed | N-Acetylcysteine as an Adjuvant Therapy in Critically Ill COVID-19 Patients: NCT05504655 | Ain Shams University | — |
| Completed | HRQOL of Life After ECMO Due to COVID-19. NCT05531032 | Medical University of Vienna | N/A |
| Completed | Nebulised BromAc in Healthy Volunteers NCT05220605 | Mucpharm Pty Ltd | Phase 1 |
| Unknown | Efficacy and Safety Evaluation of Paxlovid for COVID-19: a Real-world Case-control Study NCT05532852 | Ruijin Hospital | N/A |
| Completed | Influence of Manual Diaphragm Release on Pulmonary Functions in Women With COVID-19 NCT05903144 | Cairo University | N/A |
| Recruiting | Clinical Characteristics and Long Term Impact on Pediatric COVID-19 in Taiwan NCT05582512 | National Taiwan University Hospital | — |
| Unknown | Nebulised Heparin in Patients With COVID-19 Pneumonia NCT05255848 | Lady Reading Hospital, Pakistan | Phase 2 / Phase 3 |
| Completed | Phase I Clinical Trial of GEN2-Recombinant COVID-19 Vaccine (CHO Cells) in Healthy People Aged 18 and Above NCT05408312 | National Vaccine and Serum Institute, China | Phase 1 |
| Unknown | Effect of Slope Time in PCV Mode on Mechanical Power Calculation and Oxygenation in Covid-19 ARDS Patients. NCT05474300 | Bakirkoy Dr. Sadi Konuk Research and Training Hospital | — |
| Unknown | Angiotensin Converting Enzyme Inhibitors and Angiotensin Receptor Blockers With Risk of COVID_19 NCT05398731 | Assiut University | — |
| Completed | Factors Affecting Mortality in Covid-19 Disease NCT06043115 | Melike Cengiz | — |
| Terminated | Evaluate the Efficacy and Safety of TF0023 in Treatments for COVID-19 in Hospitalized Adults NCT05212818 | Techfields Inc | Phase 2 |
| Completed | Kesuting Syrup in the Treatment of Corona Virus Disease 2019 (COVID-19) NCT05366231 | Guizhou Bailing Group Pharmaceutical Co Ltd | Phase 4 |
| Unknown | Observational Study on the Use of Ivermectin as an Outpatient Treatment Option for COVID-19 NCT05045937 | Patrick Robinson | — |
| Withdrawn | Mesenchymal Stromal Cells for the Treatment of Patients With COVID-19. NCT05433298 | Paulo Brofman | Phase 1 / Phase 2 |
| Unknown | Safety of Nebulized Combination Therapy BromAc® in COVID-19 Respiratory Disease NCT05258682 | Mucpharm Pty Ltd | Phase 1 / Phase 2 |
| Completed | The Aerobic Exercise Capacity and Muscle Strenght in Individuals With COVID-19 NCT06272266 | Selda Sarıkaya | N/A |
| Unknown | Phase 2b/3 Trial of NuSepin® in COVID-19 Pneumonia Patients NCT05352347 | Shaperon | Phase 2 / Phase 3 |
| Withdrawn | Study of F-652 in Subjects With Corona Virus Disease 2019 (COVID-19) Pneumonia NCT05205668 | EVIVE Biotechnology | Phase 2 |
| Unknown | Women's Menstruation During the Covid-19 Pandemic NCT05197491 | Fayoum University | — |
| Completed | The Effect of Special Discharge Training in the COVID-19 NCT05867485 | Kilis 7 Aralik University | N/A |
| Completed | STUDIO DELLE MANIFESTAZIONI CARDIOVASCOLARI A LUNGO TERMINE MEDIANTE TECNICHE DI IMAGING NCT05770336 | IRCCS San Raffaele | — |
| Unknown | Recruitment Assessment in Patients With Acute Respiratory Distress Syndrome and Covid-19 NCT05248243 | Ramos Mejía Hospital | — |
| Withdrawn | Study to Evaluate the Efficacy and Safety of EG-009A Compared to DEX in Patients With COVID-19 Pneumonia NCT04561180 | Evergreen Therapeutics, Inc. | Phase 2 |
| Unknown | The Effect of Deep Breathing and Cough Exercise on Respiratory Parameters in Patients With Covid-19 Associated NCT05218200 | Özge Uçar | N/A |
| Unknown | COVID-19 Hyper Coagulability Care by LLLT NCT05271461 | Cairo University | N/A |
| Completed | The Validity of the ROX Index in Predicting Intubation in Patients With Covid-19 Pneumonia NCT05150886 | Atatürk Chest Diseases and Chest Surgery Training and Research Hospital | — |
| Unknown | Nebulized Fentanyl for Respiratory Symptoms in Patients With COVID-19 NCT05165992 | Hamad Medical Corporation | Phase 3 |
| Completed | Effects of IMT on Functional Capacity in Patients With Chronic COVID After Hospital Discharge NCT05279430 | Fundación para la Investigación del Hospital Clínico de Valencia | N/A |
| Completed | The Role of Olive Oil in the Treatment of Covid-19 Pneumonia NCT06677658 | Giresun University | — |
| Unknown | Oxygen Requirements and Use in Patients With COVID-19 in LMICs NCT04918875 | Pryanka Relan | — |
| Completed | High Velocity Nasal Insufflation Versus Continuous Positive Airway Pressure in COVID 19 Pneumonic Patients NCT07213518 | Mansoura University | N/A |
| Unknown | Dexmedetomidine Reduces Atrial Fibrillation in Mechanically Ventilated Patients With COVID-19 Pneumonia NCT05171985 | Tanta University | N/A |
| Completed | Comparison of Different Walk and Performance Test in Detecting Silent Hypoxia NCT05709262 | Kutahya Health Sciences University | — |
| Unknown | The Diagnosis of Superinfections in Mechanically Ventilated Covid-19 Patients NCT05148975 | Brno University Hospital | — |
| Completed | High-flow Nasal Oxygenation and Non-invasive Ventilation Strategies for the Treatment of Covid-19 Pneumonia NCT05137431 | Medipol University | — |
| Terminated | Usefulness of DORNASE in COVID-19 on HFNO NCT05139901 | University Medical Centre Ljubljana | Phase 4 |
| Completed | Predictive Factors for Failure of Non-invasive Support Ventilation in Patients With COVID-19: A Retrospective NCT05579080 | Universidade Federal do Rio de Janeiro | — |
| Completed | Covid-19 Pandemic and Use of Video Laryngoscopy NCT05121701 | Van Bölge Eğitim ve Araştırma Hastanesi | N/A |
| Terminated | Cromolyn Sodium for Treatment of COVID-19 Pneumonia NCT05077917 | Texas Tech University Health Sciences Center, El Paso | Phase 3 |
| Terminated | Safety, Tolerability and Efficacy of Uproleselan (GMI-1271) in Patients With COVID-19 Pneumonia NCT05057221 | Lena Napolitano, MD | Phase 1 / Phase 2 |
| Completed | Plasma SARS-CoV-2 RNA Levels in Critically Ill COVID-19 Patients NCT05115045 | Hopital of Melun | — |
| Unknown | Evaluation of Immunogenicity, Safety and Antibody Persistence of COVID-19 Booster Vaccine (Produced in Beijing NCT05104333 | China National Biotec Group Company Limited | Phase 4 |
| Unknown | Evaluation of Immunogenicity, Safety and Antibody Persistence of COVID-19 Booster Vaccine (Produced in Wuhan) NCT05104437 | China National Biotec Group Company Limited | Phase 4 |
| Unknown | Clinical Presentations and Outcomes of Patients With Covid-19 Pneumonia NCT05092555 | Sohag University | — |
| Withdrawn | LB1148 for Pulmonary Dysfunction Associated With COVID-19 Pneumonia NCT04390217 | Leading BioSciences, Inc | Phase 2 |
| Suspended | Leronlimab in Patients With Coronavirus Disease 2019 (COVID-19) With Need for Mechanical Ventilation or Extrac NCT04901689 | Hospital Israelita Albert Einstein | Phase 3 |
| Unknown | Effect of Montelukast Therapy on Clinical Course, Pulmonary Function, and Mortality in Patients With COVID-19 NCT05094596 | Bugra Kerget | Phase 4 |
| Unknown | Prognostic Value Of Chest Ultrasound (Lung Ultrasound Score) In COVID-19 Pneumonia Patients NCT05080257 | Assiut University | — |
| Completed | The Long Term Effects of COVID on Pulmonary Function NCT05077982 | Sciberras, Stephen M.D. | — |
| Terminated | Self-proning and Repositioning in COVID-19 Outpatients at Risk of Complicated Illness NCT05518474 | Unity Health Toronto | N/A |
| Completed | Effect of Prone Positioning on the Severity of COVID-19 Pneumonia and Acute Respiratory Distress Syndrome. NCT05405335 | Ayub Medical College, Abbottabad | N/A |
| Unknown | Clinical Trial on Sequential Immunization of Recombinant COVID-19 Vaccine (CHO Cells,NVSI-06-08) and Inactivat NCT05069129 | National Vaccine and Serum Institute, China | Phase 1 / Phase 2 |
| Completed | Insulin Regulation and Severity of Severe Acute Respiratory Syndrome COVID-19 Infection NCT05897528 | Arrowhead Regional Medical Center | — |
| Unknown | Effect of Covid 19 Infection on Fetomaternal Outcome NCT05160649 | Fayoum University | — |
| Completed | Pulmonary Rehabilitation After Pregnancy in COVID-19 Infection: A Case Report NCT05063799 | Dr. Lutfi Kirdar Kartal Training and Research Hospital | N/A |
| Completed | Evaluation of Immunogenicity and Safety of COVID-19 Vaccine (Produced in Beijing) in Patients With Hypertensio NCT05065879 | China National Biotec Group Company Limited | Phase 4 |
| Unknown | Adding Colchicine to Tocilizumab in Patients With Severe COVID-19 Pneumonia. NCT05118737 | Hamad Medical Corporation | EARLY_Phase 1 |
| Unknown | Evaluation of Immunogenicity and Safety of COVID-19 Vaccine (Produced in Wuhan) in Patients With Hypertension NCT05065892 | China National Biotec Group Company Limited | Phase 4 |
| Completed | Practice Variation on Antithrombotics in COVID-19 NCT04998799 | NMC Specialty Hospital | — |
| Unknown | Baseline Blood Indices and Prolonged Length of Hospital Stay NCT05054283 | Gulhane Training and Research Hospital | — |
| Completed | Efficacy of PJS-539 for Adult Patients With COVID-19. NCT05008393 | Hospital do Coracao | Phase 2 |
| Completed | The Effect of Tocilizumab on Procalcitonin and Other Biochemical and Clinical Markers in the Setting of COVID- NCT05035589 | Sciberras, Stephen M.D. | — |
| Completed | Acoustic Cough Monitoring for the Management of Patients With Known Respiratory Disease NCT05042063 | Clinica Universidad de Navarra, Universidad de Navarra | — |
| Completed | RALE Versus CORADS/CT-Severity Score in COVID-19 NCT05047653 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | — |
| Unknown | Study to Evaluate the Dynamic Consent Model Based on the Blockchain-based Clinical Trial Platform METORY NCT05047016 | Seoul National University Hospital | N/A |
| Unknown | Clinical Trial on Sequential Immunization of Recombinant COVID-19 Vaccine (CHO Cells) and Inactivated COVID-19 NCT05033847 | National Vaccine and Serum Institute, China | Phase 2 |
| Suspended | Leronlimab in Moderately Ill Patients With COVID-19 Pneumonia NCT04901676 | Hospital Israelita Albert Einstein | Phase 3 |
| Unknown | A Randomized Controlled Trial to Investigate The Role of Adjuvant Inhalable Sodium Bicarbonate Solution 8.4% i NCT05035524 | Mansoura University | N/A |
| Completed | COVID19 Oral Vaccine Consisting of Bacillus Subtilis Spores NCT05239923 | DreamTec Research Limited | N/A |
| Completed | Convolutional Neural Network Model to Detect Coronavirus Disease 2019 (COVID-19) Pneumonia in Chest Radiograph NCT05722665 | Fundacion Clinica Valle del Lili | — |
| Terminated | NIV in Covid-19 Respiratory Failure NCT05020691 | National Heatlh Service Ayrshire and Arran | — |
| Completed | Efficacy of the Early Prone-positioning in Hospitalized Patients With Mild Covid-19 Pneumonia NCT05008380 | University of Milano Bicocca | N/A |
| Completed | Coronavirus Associated Pneumomediastinum and Pneumothorax NCT04897152 | Azienda Sanitaria-Universitaria Integrata di Udine | — |
| Completed | Evaluation of Postmortem Pulmonary Interstitial Fibrosis Severity and EGFR Positivity in Covid-19 Pneumonia NCT05290441 | Bursa Yuksek Ihtisas Training and Research Hospital | N/A |
| Unknown | Atorvastatin for Reduction of 28-day Mortality in COVID-19: RCT NCT04952350 | Mansoura University | Phase 3 |
| Unknown | A Proof-of-Concept Study Evaluating EOM613 in COVID-19 Infected Patients With Severe Symptoms NCT05212532 | EOM Pharmaceuticals | Phase 1 |
| Completed | Allogeneic Natural Killer (NK) Cell Therapy in Subjects Hospitalized for COVID-19 NCT04900454 | Coeptis Therapeutics | Phase 1 |
| Unknown | Effect of Cyproheptadine on Ventilatory Support-free Days in Critically Ill Patients With COVID-19 NCT04979221 | Hospital de Clinicas de Porto Alegre | Phase 3 |
| Terminated | Real-world Evidence of COVID-19 Vaccines Effectiveness NCT04981405 | Ivan S Moiseev | — |
| Withdrawn | Baricitinib in Hospitalized Covid-19 Patients With Diabetes Mellitus NCT04970719 | Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders | Phase 3 |
| Completed | The Development of a COVID19 Oral Vaccine Consisting of Bacillus Subtilis Spores NCT05057923 | DreamTec Research Limited | N/A |
| Active Not Recruiting | Assessing the Efficacy of Sirolimus in Patients With COVID-19 Pneumonia for Prevention of Post-COVID Fibrosis NCT04948203 | University of Chicago | Phase 2 / Phase 3 |
| Completed | Retrospective Evaluation of Lung Pathology in Subjects With COVID-19 NCT04878913 | Vicore Pharma AB | — |
| Completed | Immuno-bridging Study of Inactivated SARS-CoV-2 Vaccine in Healthy Population Aged 3-17 vs Aged 18 Years Old a NCT04917523 | China National Biotec Group Company Limited | Phase 3 |
| Completed | Post COVID-19 Interstitial Lung Disease: A Study of Genetic and Environmental Interactions NCT04987606 | Imperial College London | — |
| Recruiting | Cardiac Magnetic Resonance Tissue Characterization in COVID-19 Survivors NCT05164744 | Weill Medical College of Cornell University | — |
| Unknown | Ivermectina Colombia (IVERCOL) NCT04886362 | Ayudas Diagnosticas Sura S.A.S | Phase 2 / Phase 3 |
| Completed | Tocilizumab in Covid-19 Penumonia in Buenos Aires City NCT05057962 | Sanatorio Finochietto | — |
| Unknown | Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of CKD-314 NCT04871646 | Chong Kun Dang Pharmaceutical | Phase 3 |
| Terminated | Cerebral Autoregulation and COVID-19 NCT04930874 | University of Athens | N/A |
| Completed | Clinical Impact of COVID-19 by P.1 SARS-CoV-2 Lineage NCT04928469 | Hospital de Clinicas de Porto Alegre | — |
| Completed | imPulse™ Una Infrasound-to-ultrasound E-stethoscope NCT04941209 | Level 42 AI, Inc. | — |
| Unknown | Safety and Effectiveness of an Immunobiological Drug in CoViD-19 NCT04913779 | Administracion Nacional de Laboratorios e Institutos de Salud Dr. Carlos G. Malbran | Phase 2 / Phase 3 |
| Unknown | Pilot Study for Cyproheptadine in Hospitalized Patient for COVID-19 NCT04876573 | Ciusss de L'Est de l'Île de Montréal | Phase 2 |
| Completed | Effect of Kunamin in SARS-CoV-2 RT-PCR Positive Covid-19 Patients NCT05417997 | RAAS Nutritionals, LLC | Phase 3 |
| Completed | Systemic Corticosteroids in Treatment of Post-COVID-19 Interstitial Lung Disease NCT04988282 | Turkish Thoracic Society | Phase 4 |
| Unknown | External Validation of the CHOD Risk Scale NCT04889261 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | — |
| Unknown | The Ontario Multi-Regional Hospital COVID-19 Registry (COREG)- Recovery Trajectory Sub-study NCT04868864 | Hamilton Health Sciences Corporation | — |
| Completed | The Role of High Dose Co-trimoxazole in Severe Covid-19 Patients NCT04884490 | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | Phase 2 / Phase 3 |
| Unknown | Evaluation of Immunogenicity and Safety of Combined Immunization of COVAX (Produced in Wuhan) and PPV23 / IIV4 NCT05079152 | China National Biotec Group Company Limited | Phase 4 |
| Withdrawn | Safety and Long-term Effects of COVID-19 Vaccines in Patients With Pulmonary Tumor NCT04894682 | Guangdong Provincial People's Hospital | — |
| Completed | Follow-up of Covid-19 Long Term Sequelae NCT05097677 | Azienda Ospedaliera Universitaria Integrata Verona | — |
| Completed | Investigating the Efficacy and Safety ICATIBANT For The Treatment of Patients With SARS-CoV-2 (COVID-19) Infec NCT04978051 | Sebastian Videla | Phase 2 |
| Completed | Evaluation of Serial Ultrasound Screening in ICU COVID-19 Patients NCT05028244 | Hospital Universitari Vall d'Hebron Research Institute | N/A |
| Recruiting | Study of HMB-enriched Amino Acid Supplementation in Patients With Alcoholic Liver Disease and COVID-19 NCT04858412 | The Cleveland Clinic | N/A |
| Unknown | MANS-NRIZ Trial for COVID-19 Treatment : Extension Study NCT04959786 | Mansoura University | Phase 2 / Phase 3 |
| Completed | A Novel Parameter LIT/N That Predicts Survival in COVID-19 ICU Patients NCT05520918 | Gazi University | N/A |
| Completed | Tele-rehabilitation Program After Hospitalization for COVID-19 NCT04821934 | Istituti Clinici Scientifici Maugeri SpA | N/A |
| Completed | Exercise Training Six-Months After Discharge in Post-COVID-19 Syndrome NCT05739032 | Ukbe Sirayder | N/A |
| Unknown | Embolism in COVID-19 Positive Patients NCT04910360 | Afyonkarahisar Health Sciences University | — |
| Terminated | Early Awake Alterning Prone Positioning Combined With Non-invasive Oxygen Therapy in Patients With COVID-19. NCT06076109 | Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran | N/A |
| Completed | "Clinical Characteristics, Comorbidities and Outcome of Critically Sick Patients With COVID-19 NCT05249803 | FMH College of Medicine and Dentistry | — |
| Completed | Efficacy and Safety of Antimicrobial Stewardship Intervention in Hospitalized COVID-19 Patients (COVASP) NCT04896866 | University of Alberta | N/A |
| Completed | A Retrospective Study of COVID-19 Treatments NCT04949230 | ProgenaBiome | — |
| Unknown | Breathing Effort in Covid-19 Pneumonia: Effects of Positive Pressure, Inspired Oxygen Fraction and Decubitus NCT04885517 | San Luigi Gonzaga Hospital | N/A |
| Unknown | Pain, Fatigue and Life Quality in COVID-19 Patients NCT04988126 | Afyonkarahisar Health Sciences University | — |
| Unknown | Clinical, Molecular and Functional Biomarkers for PROgnosis, Pathomechanisms and Treatment Strategies of COVID NCT04977934 | Charite University, Berlin, Germany | — |
| Completed | Evaluation of the Effectiveness of Therapy for Patients With Covid-19 Using Food Supplements Viusid + Asbrip NCT04980534 | Catalysis SL | N/A |
| Unknown | IRAK 4 Inhibitor (PF-06650833) in Hospitalized Patients With COVID-19 Pneumonia and Exuberant Inflammation. NCT04933799 | Giovanni Franchin, M.D, Ph.D | Phase 2 |
| Completed | Pilot Study of Cefditoren Pivoxil in COVID-19 Patients With Mild to Moderate Pneumonia NCT04709172 | Meiji Pharma Spain S.A. | Phase 4 |
| Unknown | Mineralocorticoid Receptor Antagonist and Pulmonary Fibrosis in COVID-19. NCT04912011 | Pomeranian Medical University Szczecin | Phase 4 |
| Completed | Comparison of the Results of Bronchoalveolar Lavage Culture and Endotracheal Aspirate Culture in Intubated Cri NCT05403489 | Basri Cakiroglu | — |
| Completed | Evaluation of the Efficacy and Safety of Nano-S1 NCT05822180 | General Administration of Military Health, Tunisia | Phase 3 |
| Unknown | Superinfection and Hyperinflammatory Phenotype in COVID-19 (Coronavirus Disease 2019) Pneumonia Patients NCT04867161 | Brno University Hospital | — |
| Completed | Association of Androgenetic Alopecia and Severity of Coronavirus Disease 2019 (COVID-19). NCT04898166 | Syeda Mahanum Ali | — |
| Unknown | Prone Positioning for Invasively Ventilated Patients With COVID-19 Registry NCT04905875 | St. Bortolo Hospital | — |
| Unknown | Tracheal Intubation in COVID-19 Patients NCT04909476 | St. Bortolo Hospital | — |
| Completed | Efficacy and Safety of Oral Immunotherapy With GcMAF in Hospitalized Patients With COVID-19 Pneumonia NCT04845971 | Dr. Spadera Lucrezia | Phase 2 |
| Completed | Hepatitis B Virus Reactivation in COVID-19 NCT07154212 | University Medical Centre Ljubljana | — |
| Withdrawn | Lanadelumab in Participants Hospitalized With COVID-19 Pneumonia NCT04460105 | Shire | Phase 1 |
| Terminated | Tofacitinib for Treatment of Moderate COVID-19 NCT04415151 | Yale University | Phase 2 |
| Completed | GM-CSF Inhalation to Prevent ARDS in COVID-19 Pneumonia NCT04569877 | University of Giessen | Phase 2 |
| Completed | Double-blind, Randomized, Controlled Clinical Trial to Assess Efficacy of MSC in Patients With COVID-19 ARDS NCT04615429 | Cristina Avendaño Solá | Phase 2 |
| Unknown | Oral Prednisone Regimens to Optimize the Therapeutic Strategy in Patients With Organizing Pneumonia Post-COVID NCT04534478 | Hospital Universitari Vall d'Hebron Research Institute | Phase 4 |
| Unknown | Randomized, Unicentric, Open, Controlled Clinical Trial, in Phase Iii, to Demonstrate the Effectiveness of Toc NCT05002517 | Biogipuzkoa Health Research Institute | Phase 3 |
| Unknown | Cyclosporine A Plus Low-steroid Treatment in COVID-19 Pneumonia NCT04540926 | Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado | Phase 1 / Phase 2 |
| Completed | Study to Verify the Effectiveness and Safety of Isothymol or Carvacrol Compound Against SARS-CoV-2 in COVID-19 NCT05445089 | Instituto Venezolano de Investigaciones Cientificas | Phase 2 / Phase 3 |
| Completed | Cutaneous Manifestations of Coronavirus Disease 2019(COVID-19). NCT05094687 | Jinnah Postgraduate Medical Centre | — |
| Completed | Multiple Dosing of Mesenchymal Stromal Cells in Patients With ARDS (COVID-19) NCT04466098 | Masonic Cancer Center, University of Minnesota | Phase 2 |
| Completed | Therapeutic Plasma Exchange Followed by Convalescent Plasma Transfusion in Severe and Critically Ill COVID-19 NCT04973488 | Novacescu Alexandru | N/A |
| Completed | Anti-inflammatory Effect of Low-Dose Whole-Lung Radiation for COVID-19 Pneumonia NCT04534790 | Instituto Mexicano del Seguro Social | N/A |
| Terminated | Efficacy and Safety Study of BDB-001 in Severe COVID-19 With ALI/ARDS NCT04449588 | Staidson (Beijing) Biopharmaceuticals Co., Ltd | Phase 2 / Phase 3 |
| Completed | Clinical Trial to Evaluate CERC-002 in Adults With COVID-19 Pneumonia and Acute Lung Injury NCT04412057 | Aevi Genomic Medicine, LLC, a Cerecor company | Phase 2 |
| Unknown | Statistical and Epidemiological Study Based on the Use of Convalescent Plasma for the Management of Patients W NCT04452812 | Universidad Autonoma de Coahuila | Phase 1 / Phase 2 |
| Completed | High Body Mass Index and Severity of Coronavirus NCT04876898 | South Valley University | — |
| Completed | NestaCell® Mesenchymal Stem Cell to Treat Patients With Severe COVID-19 Pneumonia NCT04315987 | Azidus Brasil | Phase 2 |
| Completed | A Study to Evaluate the Efficacy and Safety of Remdesivir Plus Tocilizumab Compared With Remdesivir Plus Place NCT04409262 | Hoffmann-La Roche | Phase 3 |
| Completed | A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe CO NCT04386616 | Genentech, Inc. | Phase 2 |
| Terminated | ARrest RESpiraTory Failure From PNEUMONIA NCT04193878 | Stanford University | Phase 3 |
| Completed | NO-mediated Vascular Function in Covid-19 Patient NCT04625036 | Istituti Clinici Scientifici Maugeri SpA | — |
| Unknown | Multiparametric Assessment of Peripheral Blood and Tissue Myeloid Cells. Phenotype for Precision Medicine in P NCT05767853 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Unknown | Ozone Auto-hemotherapy for COVID-19 Pneumonia NCT04370223 | Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta | Phase 3 |
| Unknown | Clinical, Virological, Serological and Immunological Characteristics During and Following COVID-19 Hospitaliza NCT05274373 | Nordsjaellands Hospital | — |
| Unknown | plasmApuane CoV-2 : Efficacy and Safety of Immune Covid-19 Plasma in Covid-19 Pneumonia in Non ITU Patients NCT04622826 | Azienda USL Toscana Nord Ovest | Phase 2 |
| Completed | Glucocorticoids in COVID-19 (CORTIVID) NCT04438980 | Fundacion Miguel Servet | Phase 3 |
| Completed | A Study to Evaluate the Efficacy and Safety of Tocilizumab in Hospitalized Participants With COVID-19 Pneumoni NCT04372186 | Genentech, Inc. | Phase 3 |
| Completed | Lung Diffusing Capacity for Nitric Oxide and Carbon Monoxide Early After Mild-to-severe COVID-19 NCT04610554 | IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy | — |
| Completed | An Open-label, Randomized, Parallel-arm Study Investigating the Efficacy and Safety of Intravenous Administrat NCT05262309 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | Phase 2 / Phase 3 |
| Unknown | Clinical Trial to Evaluate Efficacy of 3 Types of Treatment in Patients With Pneumonia by COVID-19 NCT04346147 | Hospital Universitario de Fuenlabrada | Phase 2 |
| Completed | Convalescent Plasma vs Human Immunoglobulin to Treat COVID-19 Pneumonia NCT04381858 | Centenario Hospital Miguel Hidalgo | Phase 3 |
| Completed | A Study to Investigate Intravenous Tocilizumab in Participants With Moderate to Severe COVID-19 Pneumonia NCT04363736 | Hoffmann-La Roche | Phase 2 |
| Terminated | Trial of Open Label Dipyridamole- In Hospitalized Patients With COVID-19 NCT04424901 | UConn Health | Phase 2 |
| Unknown | Treatment of Coronavirus COVID-19 Pneumonia (Pathogen SARS-CoV-2) With Cryopreserved Allogeneic P_MMSCs and UC NCT04461925 | Institute of Cell Therapy | Phase 1 / Phase 2 |
| Unknown | ACT-20 in Patients With Severe COVID-19 Pneumonia NCT04398303 | Aspire Health Science | Phase 1 / Phase 2 |
| Completed | Treatment of Severe COVID-19 Pneumonia With Allogeneic Mesenchymal Stem Cells NCT04361942 | Red de Terapia Celular | Phase 2 |
| Withdrawn | Hydroxychloroquine for the Treatment of SARS-CoV2 (COVID 19) : Pharmacokinetic Study NCT04625218 | University Hospital, Toulouse | — |
| Unknown | Azithromycin+Amoxicillin/Clavulanate vs Amoxicillin/Clavulanate in COVID19 Patients With Pneumonia in Non-inte NCT04363060 | Nantes University Hospital | Phase 3 |
| Completed | Tocilizumab and Cytokine Release Syndrome (CRS) In Covid-19 Pneumonia NCT04873141 | Shaheed Zulfiqar Ali Bhutto Medical University | — |
| Unknown | Neuromuscular Electrical Stimulation in Patients With COVID19 Associated Pneumonia NCT04382729 | University of Turin, Italy | N/A |
| Unknown | Screening COVID-19 by Point-of-care Lung Ultrasound: a Validation Study NCT04338568 | Hasselt University | N/A |
| Completed | A Study to Evaluate the Safety and Efficacy of Tocilizumab in Patients With Severe COVID-19 Pneumonia NCT04320615 | Hoffmann-La Roche | Phase 3 |
| Unknown | Efficacy and Safety of Tocilizumab in the Treatment of SARS-Cov-2 Related Pneumonia NCT04332913 | University of L'Aquila | — |
| Unknown | Diaphragm Ultrasound Evaluation During Weaning From Mechanical Ventilation in the Positive COVID-19 Patient NCT05019313 | Azienda Sanitaria-Universitaria Integrata di Udine | — |
| Not Yet Recruiting | Adipose Mesenchymal Cells for Abatement of SARS-CoV-2 Respiratory Compromise in COVID-19 Disease NCT04352803 | Regeneris Medical | Phase 1 |
| Terminated | Efficacy of Early Administration of Tocilizumab in COVID-19 Patients NCT04346355 | Azienda USL Reggio Emilia - IRCCS | Phase 2 |
| Completed | A New Scoring Model to Diagnose COVID-19 Using Lung Ultrasound in the Emergency Department NCT05077202 | Zagazig University | — |
| Completed | Ozone Therapy and Coronavirus Disease of 2019 (COVID-19) Pneumonia NCT04444531 | Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta | — |
| Completed | A Different Use of The Aerosol Box in COVID-19 Patients; Internal Jugular Vein Cannulation NCT04954118 | Bakirkoy Dr. Sadi Konuk Research and Training Hospital | N/A |
| Unknown | Tocilizumab in COVID-19 Pneumonia (TOCIVID-19) NCT04317092 | National Cancer Institute, Naples | Phase 2 |
| Unknown | Reliability of a Pocket Sized Ultrasound Scanner in the Evaluation Covid-19 Pneumonia NCT04433000 | University of Siena | — |
| Withdrawn | Chloroquine + Losartan Compared to Chloroquine Alone for the Treatment of COVID-19 Pneumonia NCT04428268 | Hospital Universitario Dr. Jose E. Gonzalez | Phase 2 |
| Completed | An Investigation on the Role of Emergency Departments in Combatting Against COVID-19 in Zhejiang Province NCT04915001 | Second Affiliated Hospital, School of Medicine, Zhejiang University | — |
| Unknown | Assessment of Long-term Sequelae of Coronavirus Disease 2019 (COVID-19) Pneumonia With Chest CT and Pulmonary NCT05835128 | Centro Hospitalar Universitario do Algarve | — |
| Completed | Safety and Feasibility of Percutaneous Dilatational Tracheostomy in Patients With Severe COVID-19 Supported by NCT05045885 | Hamad Medical Corporation | — |
| Unknown | Safety and Effectiveness of Mesenchymal Stem Cells in the Treatment of Pneumonia of Coronavirus Disease 2019 NCT04371601 | Fuzhou General Hospital | EARLY_Phase 1 |
| Unknown | University Hospital of Ioannina COVID-19 (Coronavirus Disease 2019) Registry NCT05534074 | University Hospital, Ioannina | — |
| Completed | Use of Compromised Lung Volume in Monitoring Usage of Steroid Therapy on Severe COVID-19 NCT04953247 | Guowei Tu | — |
| Completed | Acute Kidney Injury in Coronavirus Disease-19 (COVID-19) Patients Admitted to the Intensive Care Unit (ICU) NCT04997915 | University Hospital, Ghent | — |
| Unknown | Use of Low-frequency Magnetic Fields in the Hybrid Treatment of COVID-19 Patients NCT05163613 | Medical University of Lodz | N/A |
| Recruiting | Retrospective Analysis of Chest X-ray Severity Scoring System of COVID-19 Pneumonia NCT05181696 | Osijek University Hospital | — |
| Completed | A Proof of Concept Study for the DNA Repair Driven by the Mesenchymal Stem Cells in Critical COVID-19 Patients NCT04898088 | SBÜ Dr. Sadi Konuk Eğitim ve Araştırma Hastanesi | N/A |