NCT05238623

Imbalances of Regional Pulmonary Ventilation in Patients With Post-acute-COVID-19

Imbalances of Regional Pulmonary Ventilation in Patients With Post-acute-COVID-19 Symptoms

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 50 (estimated)
• Sponsor: Jan-Christoph Lewejohann · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Investigation of the correlation of CT-morphological changes of the lung compared to regional ventilation distribution on electrical impedance tomography in patients with post-acute-Covid-19 symptoms.

Detailed description

Prospective non-interventional, monocentric observational study on imbalances in regional lung ventilation compared to chest CT in post-acute-Covid-19. The aim is to verify the agreement between computerized tomography derived imaging variables and electrical impedance tomography in detecting lung ventilation imbalances. The primary study objective is to match CT morphological changes in regional ventilation in post-acute-COVID-19 patients and/or changes in lung function examination, with changes that can be visualized by electroimpedance tomography.

Conditions

• COVID-19 Pneumonia
• Post-acute COVID-19 Syndrome
• Electric Impedance

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	additional EIT Measurement	Patients who receive standard CT and pulmonary function testing also receive electroimpedance tomography measurement. The lunghealthy Patients in the control group only receive a EIT.

Timeline

• Start date: 2025-10-01
• Primary completion: 2026-06-30
• Completion: 2027-03-31
• First posted: 2022-02-14
• Last updated: 2025-09-25

Locations

1 site across 1 country: Germany