| Recruiting | Cardiac Self-Efficacy in Patients With Chronic Thromboembolic Pulmonary Hypertension NCT07272798 | Damascus University | — |
| Recruiting | Registry of Patients With chrOnic thromboemboLic Pulmonary hypErTension NCT07254078 | Irina E. Chazova | — |
| Recruiting | Riociguat-Discontinue Effects on Right HEART in CTEPH (RED-HEART) NCT06922240 | Suqiao Yang | Phase 3 |
| Recruiting | Chronic Thromboembolic Pulmonary Hypertension After Pulmonary Embolism NCT06081881 | Ester Ashraf Faried Beshay | — |
| Recruiting | Switching of Sildenafil to Riociguat in CTEPH Patients NCT06715280 | Chinese University of Hong Kong | Phase 4 |
| Completed | Exercise Performance on Ambient Air vs. Low-Flow Oxygen Therapy in Pulmonary Vascular Disease (PVD) NCT06384534 | University of Zurich | N/A |
| Enrolling By Invitation | Balloon Pulmonary Angioplasty vs. Combined Approach With Pulmonary Artery Denervation in CTEPH: Effectiveness NCT06209710 | Boris Dzudovic | Phase 2 / Phase 3 |
| Recruiting | BPA vs. PEA in CTEPH NCT05110066 | University of Aarhus | N/A |
| Recruiting | Frailty, Physical Capacity and Lung Function in Postoperative Pulmonary Endarterectomy Patients NCT06286891 | University of Sao Paulo General Hospital | — |
| Recruiting | 129Xe MRI Cardiopulmonary NCT06038630 | Bastiaan Driehuys | Phase 2 |
| Unknown | Impact of Pulmonary Endarterectomy on Sleep-Related Breathing Disorders in CTEPH: The IPES Trial NCT06060366 | Marmara University | — |
| Unknown | High Altitude (HA) Residents With Pulmonary Vascular Diseases (PVD), 6 Minute Walk Distance (6MWD) Assessed at NCT06003244 | University of Zurich | N/A |
| Unknown | High Altitude (HA) Residents With Pulmonary Vascular Diseseases (PVD), Pulmonary Artery Pressure (PAP) Assesse NCT06092424 | University of Zurich | N/A |
| Unknown | HA Residents With PVD, SDB Assessed at HA (2840m) vs LA (Sea Level) NCT06072417 | University of Zurich | N/A |
| Recruiting | Chronic Thromboembolic Disease Registry NCT05843500 | University of California, San Francisco | — |
| Unknown | HA Residents With PVD, 6MWD Assessed at HA (2840m) vs LA (Sea Level) NCT05996302 | University of Zurich | N/A |
| Unknown | HA Residents With PVD, Pulmonary Artery Pressure (PAP) Assessed at HA (2840m) With and Without Supplemental Ox NCT06084559 | University of Zurich | N/A |
| Withdrawn | Exercise Therapy After Pulmonary Thromboendarterectomy or Balloon Pulmonary Angioplasty for Chronic Thromboemb NCT05693779 | University of Michigan | N/A |
| Active Not Recruiting | TrEatment Approach in the Multimodal Era Registry NCT05629052 | International CTEPH Association | — |
| Withdrawn | Non-Invasive Measurement of Cardiac Output and Stroke Volume in PAH/CTEPH NCT05618093 | University of California, Los Angeles | N/A |
| Completed | Dapagliflozin in Pulmonary Arterial Hypertension NCT05179356 | Mads Ersbøll | Phase 2 |
| Completed | Validation of SEARCH, a Novel Hierarchical Algorithm to Define Long-term Outcomes After Pulmonary Embolism NCT05568927 | University of California, San Diego | — |
| Recruiting | Proteomic Pattern Associated With the Diagnosis of Chronic Thromboembolic Pulmonary Hypertension NCT05340023 | Centre Hospitalier Universitaire de Saint Etienne | — |
| Terminated | Effects of Riociguat on RIght VEntricular Size and Function in PAH and CTEPH NCT04954742 | Heidelberg University | Phase 4 |
| Unknown | Ventilation and Perfusion Scan in Pulmonary Embolism Following Catheter Directed Thrombectomy Versus Anticoagu NCT05133713 | University of Arizona | — |
| Unknown | RV Conductance Catheter Assessment During Balloon Pulmonary Angioplasty NCT04444973 | Papworth Hospital NHS Foundation Trust | — |
| Completed | Right Atrial Fibrosis in Pulmonary Hypertension NCT04663230 | University of Giessen | — |
| Unknown | Optimized Management After Balloon Pulmonary Angioplasty in Chronic Thromboembolic Pulmonary Hypertension NCT04777448 | University Hospital, Grenoble | N/A |
| Unknown | Hemodynamic Effects of BPA at Rest and During Exercise in CTEPH NCT04052243 | Aarhus University Hospital | N/A |
| Recruiting | Pulmonary Hypertension Biorepository and Registry NCT04808596 | University of Kansas Medical Center | — |
| Terminated | A Study to Evaluate Efficacy and Safety of Macitentan 75 mg in Inoperable or Persistent/Recurrent Chronic Thro NCT04271475 | Actelion | Phase 3 |
| Completed | The Role of Matrix Metalloproteinase 2 and 9 Enzymes in Developing Chronic Thromboembolic Pulmonary Hypertensi NCT04773028 | AHMET ZENGIN | — |
| Unknown | COVID-19 Pneumonia: Pulmonary Physiology, Health-related Quality of Life and Benefit of a Rehabilitation Progr NCT04881214 | University Hospital, Geneva | N/A |
| Unknown | Clinical Study of Balloon Pulmonary Angioplasty for Patients With Chronic Thromboembolic Pulmonary Hypertensio NCT04326777 | Li Xuyan | N/A |
| Unknown | N-acetyl Cysteine in Post-reperfusion Pulmonary Injury in Chronic Thromboembolic Pulmonary Hypertension. NCT04081012 | Instituto Nacional de Cardiologia Ignacio Chavez | N/A |
| Unknown | Iodine Subtraction Mapping in the Diagnosis of Chronic Pulmonary Thromboembolic Disease NCT03806907 | University of Sheffield | — |
| Completed | Computerized Decision Support to Increase Detection of Chronic Thromboembolic Pulmonary Hypertension in Patien NCT03729544 | Brigham and Women's Hospital | N/A |
| Terminated | A Study to Find Out if Selexipag is Effective and Safe in Patients With Chronic Thromboembolic Pulmonary Hyper NCT03689244 | Actelion | Phase 3 |
| Completed | Dyspnea in Chronic Thromboembolic Pulmonary Hypertension NCT03786367 | Dr. Denis O'Donnell | — |
| Terminated | Riociguat in Patients With Operable CTEPH Prior to Pulmonary Endarterectomy (PEA Bridging Study) NCT03273257 | International CTEPH Association | Phase 2 |
| Recruiting | Safety and Efficacy of Balloon Pulmonary Angioplasty in China NCT04206852 | Chinese Pulmonary Vascular Disease Research Group | — |
| Enrolling By Invitation | Endtidal Carbon Dioxide for Earlier Detection of Pulmonary Hypertension NCT03388476 | University of Giessen | — |
| Unknown | The Prospective Risk Factor Evaluation & Discovery In CTEPH Study NCT03470207 | Mark W. Dodson | N/A |
| Completed | A Clinical Study to Investigate the Long-term Safety of the Drug Macitentan in Patients With Pulmonary Hyperte NCT03422328 | Actelion | Phase 3 |
| Completed | International BPA Registry NCT03245268 | International CTEPH Association | — |
| Recruiting | DataBase of pulmoNary hyPertesion in PoLish Population - BNP-PL NCT03959748 | Polish Cardiology Association | — |
| Completed | Long-term Outcome After Heparin and Edoxaban Versus Heparin Plus Vit K Antagonists for Acute DVT and PE NCT03757481 | University Hospital, Montpellier | N/A |
| Completed | Inspiratory Muscle Training in Pulmonary Hypertension NCT03102294 | Federal University of São Paulo | N/A |
| Completed | Retrospective Data Analysis of Data From the Zurich PH Registry NCT03198910 | University of Zurich | — |
| Unknown | Long-term Outcome After Edoxaban Versus Vitamin K Antagonists for Acute VTE NCT04007653 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | — |
| Completed | The Right Ventricle in Chronic Pressure Overload: Identifying Novel Molecular Targets for Functional Imaging NCT03199131 | Centre Chirurgical Marie Lannelongue | N/A |
| Completed | Sleep-Disordered Breathing in Chronic Thromboembolic Pulmonary Hypertension NCT03074539 | Medical University of Vienna | N/A |
| Unknown | Pulmonary Endarterectomy Guided by CT Scanning for Patients With Chronic Thromboembolic Pulmonary Hypertension NCT03795740 | Sheng Liu | N/A |
| Unknown | Registry of Patients With Chronic Thromboembolic Pulmonary Hypertension in Novosibirsk Region NCT03349164 | Novosibirsk Scientific Research Institute for Circulatory Pathology | — |
| Completed | Early Non-invasive Detection of CTEPH After Pulmonary Embolism NCT02555137 | Leiden University | — |
| Unknown | CTEPH in Patients With Prior Pulmonary Embolism and Risk Score Validation NCT04681014 | iPHNET (italian Pulmonary Hypertension NETwork) | — |
| Completed | Riociguat Versus Balloon Pulmonary Angioplasty in Non-operable Chronic thromboEmbolic Pulmonary Hypertension NCT02634203 | Assistance Publique - Hôpitaux de Paris | N/A |
| Unknown | Prospective Registry to Evaluate the Effective Incidence of Chronic Thromboembolic Pulmonary Hypertension in G NCT02660463 | Kerckhoff Klinik | — |
| Recruiting | Pulmonary Hypertension Association Registry NCT04071327 | Pulmonary Hypertension Association, Inc. | — |
| Recruiting | Change-a Multi-center Chronic Thromboembolic Pulmonary Hypertension （CTEPH） Database in China NCT05311072 | China-Japan Friendship Hospital | — |
| Unknown | Interventional Treatment of Residual Pulmonary Hypertension in Patients After Pulmonary Thromboendarterectomy NCT02745106 | Novosibirsk Scientific Research Institute for Circulatory Pathology | Phase 2 |
| Unknown | 3D Echocardiographic Assessment of RV Function in Patients Undergoing Pulmonary Endarterectomy NCT02426203 | Papworth Hospital NHS Foundation Trust | — |
| Unknown | Assessment of Blood Coagulation Disorders in Patients With Pulmonary Hypertension NCT03195543 | National and Kapodistrian University of Athens | — |
| Completed | Clinical Study to Assess the Safety, Tolerability and Efficacy of Macitentan in Subjects With Inoperable Chron NCT02060721 | Actelion | Phase 2 |
| Completed | Chronic Thrombo-embolic Pulmonary Hypertension: Classification and Long Term Outcome NCT02565030 | Sheffield Teaching Hospitals NHS Foundation Trust | — |
| Completed | New International CTEPH Database NCT02656238 | International CTEPH Association | — |
| Completed | Prognostic Value of Estimated Plasma Volume in Pulmonary Hypertension NCT05861479 | Central Hospital, Nancy, France | — |
| Completed | Clinical Study to Assess the Efficacy, Safety and Tolerability of Macitentan in Subjects With Inoperable Chron NCT02021292 | Actelion | Phase 2 |
| Completed | Pilot Study to Evaluate Right Ventricular Function With Riociguat in CTEPH NCT02094001 | Ottawa Heart Institute Research Corporation | Phase 2 |
| Terminated | Sleep Disordered Breathing in Precapillary Pulmonary Hypertension: Effect of CPAP Treatment NCT02583906 | Universitaire Ziekenhuizen KU Leuven | N/A |
| Completed | RF Surgical Sponge-Detecting System on the Function of Pacemakers and Implantable Cardioverter Defibrillators NCT02111980 | University of California, San Diego | N/A |
| Completed | Pulmonary Perfusion Heterogeneity in Patients With CTEPH Using Functional PET Imaging NCT02114047 | Massachusetts General Hospital | — |
| Unknown | Long Term Outcomes of Venous Thromboembolism NCT02268630 | Ostfold Hospital Trust | — |
| Unknown | Identification of Heritable CTEPH NCT03579862 | Intermountain Health Care, Inc. | — |
| Unknown | Balloon Pulmonary Angioplasty in Non-operable CTEPH Patients NCT02964390 | Department of Pulmonary Circulation and Thromboembolic Diseases, Medical Center for Postgraduate Med | N/A |
| Recruiting | Chinese PE Multimodality Imaging Artificial Intelligence Study NCT06526468 | China-Japan Friendship Hospital | — |
| Recruiting | the Application of Cardiopulmonary Exercise Testing in Assessment Outcome of Patients With Pulmonary Hypertens NCT02061787 | Chinese Pulmonary Vascular Disease Research Group | — |
| Unknown | Right Ventricular Resynchronization Therapy NCT01163422 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Unknown | Registry for Pulmonary Hypertension in China NCT01417338 | Chinese Academy of Medical Sciences, Fuwai Hospital | — |
| Completed | Lung Protective Ventilation in Pulmonary Thromboendarterectomy (PTE) Patients NCT00747045 | University of California, San Diego | N/A |
| Completed | Identification of Criteria of the Success of the Endarterectomy in Chronic Pulmonary Post Embolic Hypertension NCT00657722 | Assistance Publique - Hôpitaux de Paris | N/A |
| Unknown | Latent Pulmonary Hypertension (PH) in Chronic Thromboembolic Pulmonary Hypertension (CTEPH )After Endarterecto NCT00477724 | Heidelberg University | N/A |
| Completed | Bosentan Effects in Inoperable Forms of Chronic Thromboembolic Pulmonary Hypertension NCT00313222 | Actelion | Phase 3 |
| Unknown | Gene Mutations in Secondary Pulmonary Hypertension NCT00348803 | Medical University of Vienna | — |