Trials / Terminated
TerminatedNCT02583906
Sleep Disordered Breathing in Precapillary Pulmonary Hypertension: Effect of CPAP Treatment
- Status
- Terminated
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 8 (actual)
- Sponsor
- Universitaire Ziekenhuizen KU Leuven · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Evaluation of the effect of CPAP (continuous positive airway pressure ) treatment in PAH (pulmonary arterial hypertension) and CTEPH (chronic thromboembolic pulmonary hypertension) patients suffering from sleep disordered breathing.
Detailed description
The primary endpoint of the study is to evaluate the effect of CPAP therapy on pulmonary vascular resistance in PAH and CTEPH patients suffering from sleep disordered breathing. The secondary endpoints are the effect of CPAP on right atrium and right ventricle diameter and ejection fraction measured by echocardiography, 6 minutes walk distance, NYHA class, QOL, endothelial function, sympathetic activity and prognosis.
Conditions
- Sleep-Disordered Breathing
- Pulmonary Arterial Hypertension
- Chronic Thromboembolic Pulmonary Hypertension
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | CPAP | Treatment with CPAP for six months in the CPAP arm. |
Timeline
- Start date
- 2014-04-01
- Primary completion
- 2019-05-01
- Completion
- 2019-05-01
- First posted
- 2015-10-22
- Last updated
- 2023-01-27
Locations
1 site across 1 country: Belgium
Source: ClinicalTrials.gov record NCT02583906. Inclusion in this directory is not an endorsement.