| Recruiting | Copper Supplementation in Cirrhosis NCT07471542 | University of Washington | N/A |
| Not Yet Recruiting | To Study the Clinical Course and Outcomes of Non-electively Hospitalised Patients of Chronic Liver Disease (CL NCT07270809 | Institute of Liver and Biliary Sciences, India | — |
| Recruiting | Endoscopic Ultrasound Shear Wave Elastography Study NCT06592820 | Olympus Corporation of the Americas | — |
| Completed | Comparing Portal Vein Assessment by Intraoperative Doppler and Transesophageal Echocardiography NCT06909175 | Institute of Liver and Biliary Sciences, India | — |
| Not Yet Recruiting | Efficacy of Plasmapheresis in Patients of Drug-Induced Liver Injury (DILI) With Underlying Chronic Liver Disea NCT06797011 | Institute of Liver and Biliary Sciences, India | Phase 2 / Phase 3 |
| Recruiting | Albumin Modifications as Early Biomarkers of Chronic Liver Diseases NCT06318949 | University Hospital, Limoges | N/A |
| Recruiting | Effect of Perioperative Oral Rifaximin on Early Graft Dysfunction in Adult Living Donor Liver Transplant NCT06743464 | Institute of Liver and Biliary Sciences, India | N/A |
| Active Not Recruiting | Mobile Chat Messaging for Alcohol Reduction in Patients With Chronic Liver Diseases NCT06587568 | The University of Hong Kong | N/A |
| Enrolling By Invitation | Somatic Mutation in Chronic Liver Disease NCT06656767 | The Wellcome Sanger Institute | — |
| Recruiting | In Patients With Chronic Liver Diseases(Alcoholic Liver Disease and Non-Alcoholic Fatty Liver Disease), LAENNE NCT06493799 | Green Cross Wellbeing | Phase 3 |
| Enrolling By Invitation | Study on the Efficacy and Safety of Avatricopal in Patients With CLD Complicated With Thrombocytopenia NCT06642740 | Beijing Ditan Hospital | — |
| Recruiting | hepatomiR cACLD Study NCT06432582 | Karl Landsteiner University of Health Sciences | — |
| Not Yet Recruiting | Referral of Patients to Hepatology With Hepatoscope NCT06387745 | University Hospital, Antwerp | N/A |
| Recruiting | Measuring Patient Reported Needs in Outpatient Liver Disease Management NCT07191886 | Indiana University | — |
| Enrolling By Invitation | An Observational Study of Patients With Chronic Liver Disease NCT05744713 | Target PharmaSolutions, Inc. | — |
| Not Yet Recruiting | Evaluating the Diagnostic and Predictive Value of Non-invasive Tests (NITs) on the Progression of Chronic Live NCT05312853 | Johannes Gutenberg University Mainz | — |
| Unknown | Intervention, Prognosis and Mechanism of Covid-19 Infection in Patients With Underlying Diseases NCT05965843 | The Second Affiliated Hospital of Chongqing Medical University | — |
| Unknown | ASSESSMENT OF SURGICAL RISK IN PATIENTS WITH CHRONIC LIVER DISEASE USING VOCAL PENN SCORE NCT06227988 | Asian Institute of Gastroenterology, India | — |
| Unknown | Effectiveness of Oral Lactulose Versus Lactulose Enema in Hepatic Encephalopathy NCT05788627 | Khyber Medical College, Peshawar | Phase 4 |
| Unknown | Comparison Between Thromboelastography and Conventional Coagulation Tests in Pediatrics With Chronic Liver Dis NCT05809141 | Assiut University | — |
| Recruiting | D-SOLVE Cohorts (Cohort a and B) NCT06160635 | Hannover Medical School | — |
| Active Not Recruiting | VIATORR Device Registry NCT05661331 | W.L.Gore & Associates | — |
| Completed | Study to Evaluate the Efficacy and Safety of DWJ1464 in Patients with Chronic Liver Disease NCT06272630 | Daewoong Pharmaceutical Co. LTD. | Phase 4 |
| Recruiting | FAST-IRM for HCC suRveillance in pAtients With High risK of Liver Cancer. NCT05095714 | Assistance Publique - Hôpitaux de Paris | N/A |
| Unknown | Observational Clinical Study of the Natural Course and Long-term Prognosis of Patients With Chronic Liver Dise NCT05653830 | First Affiliated Hospital Xi'an Jiaotong University | — |
| Withdrawn | A Study to Evaluate Vaccines Against COVID-19 in the Real World NCT04775056 | Humanity & Health Medical Group Limited | — |
| Unknown | Elastography in Chronic Liver Disease in Children NCT04774601 | Assiut University | — |
| Unknown | Evaluation of the Quality of Life in Patients Referred for Transjugular Intrahepatic Portosystemic Shunt NCT05204251 | University Hospital, Strasbourg, France | — |
| Unknown | Delta Radiomics for Liver Function Evaluation NCT05296434 | Zhujiang Hospital | — |
| Completed | Comparison of the Acute Effects of Chest Physiotherapy Methods Applied in Different Positions in Preterm Newbo NCT05036603 | Sanko University | N/A |
| Unknown | Study to Compare the Efficacy & Safety of Ursoplus Capsules vs. UDCA vs. Placebo Among Chronic Liver Disease P NCT05849558 | MinaPharm Pharmaceuticals | Phase 4 |
| Completed | Comparative Efficacy of Liver Fibrosis and Steatosis Assessment With Fibroscan and iLivTouch NCT05224037 | Federal State Budgetary Scientific Institution "Federal Research Centre of Nutrition, Biotechnology | N/A |
| Completed | A Study to Evaluate Liver Stiffness With Shear Wave Elastography NCT05097963 | Mayo Clinic | N/A |
| Completed | EUS vs TJ for Liver Biopsy and Portal Pressure Gradient Measurement NCT05118308 | McGill University Health Centre/Research Institute of the McGill University Health Centre | N/A |
| Completed | Liver and Splenic Stiffness in Predicting Esophageal Varices Needing Treatment in MASLD Related Compensated Ad NCT05044663 | Institute of Liver and Biliary Sciences, India | — |
| Completed | Risk Stratification of Hepatocarcinogenesis Using a Deep Learning Based Clinical, Biological and Ultrasound Mo NCT04802954 | IHU Strasbourg | N/A |
| Unknown | Efficacy of Avatrombopag in Thrombocytopenic Patients With Chronic Liver Disease Undergoing an Elective Proced NCT04915287 | Chinese PLA General Hospital | Phase 4 |
| Completed | Part A: In Patients With Chronic Liver Diseases, LAENNEC (Human Placenta Hydrolysate) is to Assess Safety and NCT05532124 | Green Cross Wellbeing | Phase 2 |
| Completed | Antibody Response to COVID-19 Vaccines in Liver Disease Patients NCT04775069 | Humanity & Health Medical Group Limited | Phase 4 |
| Completed | 19Gauge Fine Needle Biopsy (FNB) Versus 22Gauge FNB for Endoscopic Ultrasound Guided Liver Biopsy (EUS-LB) NCT04806607 | Geisinger Clinic | N/A |
| Completed | Comparison and Outcomes of Endoscopic Ultrasound Liver Biopsies Versus Percutaneous Liver Biopsies NCT04751045 | University of Missouri-Columbia | N/A |
| Unknown | A Diagnostic Study on Patients With Drug-induced Liver Injury NCT04526548 | Drug Induced Liver Disease Study Group | — |
| Recruiting | Comparison Between 2-dose Versus 3-dose Regimens of Heplisav B in Cirrhosis NCT04588077 | Mercy Medical Center | Phase 4 |
| Unknown | Etiopathogenesis of Anemia in Chronic Liver Disease NCT04622449 | Post Graduate Institute of Medical Education and Research, Chandigarh | — |
| Unknown | The Development of Quantitative Ultrasound Imaging Software Platform NCT05836246 | Seoul National University Bundang Hospital | — |
| Recruiting | An Observational Study Evaluating Patients With Chronic Liver Diseases Associated With Hepatic Steatosis NCT05335603 | University of Copenhagen | — |
| Completed | Effect of Midodrine on HVPG in Advanced Chronic Liver Disease NCT04455464 | Institute of Liver and Biliary Sciences, India | N/A |
| Completed | Effect of BCAA Supplementation on Muscle Mass, Muscle Quality and Molecular Markers of Muscle Regeneration in NCT04246918 | Institute of Liver and Biliary Sciences, India | N/A |
| Completed | COVID-19 in Patients With Chronic Liver Diseases NCT04439084 | Stanford University | — |
| Completed | Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BLD-0409 in Healthy Subjects NCT04146805 | Blade Therapeutics | Phase 1 |
| Unknown | Radiofrequency Ablation With Gradual Radiofrequency Energy Increment for Hepatocellular Carcinoma Treatment NCT05397860 | Seoul National University Hospital | N/A |
| Withdrawn | FDGal PET/CT to Detect Hepatocellular Carcinoma NCT02899325 | British Columbia Cancer Agency | — |
| Completed | Validation of the Second Generation of the Controlled Attenuation Parameter (CAP) Using the MRI-PDFF as Refere NCT03704792 | Echosens | N/A |
| Completed | Pirfenidone and Advanced Liver Fibrosis. NCT04099407 | Grupo Mexicano para el Estudios de las Enfermedades Hepaticas | Phase 2 |
| Unknown | Efficacy and Safety of Plasma Exchange Compared to Standard Medical Therapy in Patients With Severe Drug Induc NCT04015570 | Institute of Liver and Biliary Sciences, India | N/A |
| Completed | The SHUNT-V Study for Varices NCT03583996 | HepQuant, LLC | N/A |
| Unknown | Evaluation of the Mechanisms of Sarcopenia in Chronic Inflammatory Disease: Protocol for a Prospective Cohort NCT04734496 | University of Birmingham | — |
| Completed | Impact of Counselling and Visual Aid on Anxiety in Endoscopic Patients NCT05241158 | King Edward Medical University | N/A |
| Unknown | Non Invasive Electrical Impedance Technology (EIT) for Diagnosing Liver Diseases Severity NCT03492879 | Prof. Ziv Ben-Ari MD | N/A |
| Completed | Postprandial Liver and Spleen Stiffness Measurements in the Noninvasive Diagnosis of Cirrhosis NCT03087344 | VA Connecticut Healthcare System | N/A |
| Completed | Efficacy and Safety of Sodium Benzoate in the Management of Hyperammonemia in Infants, Children and Adolescent NCT04022941 | Institute of Liver and Biliary Sciences, India | N/A |
| Completed | Proof of Concept Study Concerning Efficacy of P03277 MR Imaging in HCC Diagnosis NCT02973516 | Guerbet | Phase 2 |
| Completed | Superior Silybin Bioavailability in Healthy Volunteers NCT03440164 | Medica Sur Clinic & Foundation | — |
| Unknown | Blood Ammonia as Predictor for Esophageal Varices and Risk of Bleeding NCT03212872 | Tanta University | N/A |
| Completed | Nutritional Assessment Tool in Childhood Chronic Liver Disease NCT02802761 | Institute of Liver and Biliary Sciences, India | — |
| Completed | Long Term Follow-up of Hepatitis C Cured Patients NCT03246048 | Hospital Universitari Vall d'Hebron Research Institute | — |
| Completed | Nutritional Assessment Tool and Nutritional Intervention in Childhood Chronic Liver Disease NCT02715973 | Institute of Liver and Biliary Sciences, India | N/A |
| Suspended | Clinical Features and Natural History of Acute-on-Chronic Liver Failure in Korean Patients With Chronic Liver NCT02650011 | Chuncheon Sacred Heart Hospital | — |
| Terminated | Non-invasive Evaluation of Portal Pressure by MRI NCT02530567 | University Hospital, Toulouse | N/A |
| Terminated | Trial to Examine the Effect of Two Doses of GRI-0621 in Patients With Chronic Liver Disease NCT02949375 | GRI Bio Operations, Inc. | Phase 2 |
| Completed | Prolonged Release Pirfenidone Versus Placebo in Compensated Cirrhosis. NCT06267794 | Jorge L Poo | Phase 2 |
| Completed | Safety and Efficacy Study of Lusutrombopag for Thrombocytopenia in Patients With Chronic Liver Disease Undergo NCT02389621 | Shionogi | Phase 3 |
| Completed | The Use of the Transient Elastography Paediatric Probe, Compared to the M Probe, Indirect Biomarkers and Histo NCT04380493 | Hospital Vall d'Hebron | — |
| Terminated | Study Evaluating Novel Biomarkers of AKI (Acute Kidney Injury) in Post-operative Patients NCT02499185 | Universitair Ziekenhuis Brussel | Phase 4 |
| Unknown | PatientSpot Formerly Known as ArthritisPower NCT03840928 | Global Healthy Living Foundation | — |
| Completed | Therapeutic Approach to Diastolic Dysfunction in Chronic Liver Disease Patients and Its Impact on Morbidity an NCT02294292 | Institute of Liver and Biliary Sciences, India | N/A |
| Completed | Determination of Liver Stiffness in Chronic Liver Disease Patients by Acoustic Radiation Force Imaging (ARFI) NCT02652221 | Children's Hospital Medical Center, Cincinnati | N/A |
| Completed | Prediction Value of the BreathID 13C-Methacetin Breath Test for Hepatic Decompensation NCT02084160 | Meridian Bioscience, Inc. | — |
| Unknown | The Role of Strain Elastography in Staging Liver Fibrosis NCT02184000 | University of Medicine and Pharmacy Craiova | — |
| Recruiting | Prognosis Value of Non-invasive Methods for the Diagnosis of Chronic Liver Disease NCT02060565 | Association HGE CHU Bordeaux Sud | — |
| Unknown | Prospective Studies on Immunopathogenesis of Liver Fibrosis NCT04943978 | University of Regensburg | — |
| Completed | Comparison of Response and Recurrence Rates Following Percutaneous Microwave Coagulation Therapy Versus Percut NCT02859753 | Centre Hospitalier Universitaire Dijon | N/A |
| Unknown | Hepatic Venous Pressure Gradient and Platelet Activation in Chronic Liver Disease NCT02618798 | Medical University of Vienna | — |
| Completed | Stratification of Patients With Chronic Liver Disease Using Multi Spectral CT NCT01825213 | Massachusetts General Hospital | — |
| Completed | MBT Versus HVPG in Identifying Responders to Portal Hypertension Therapy NCT01851252 | Meridian Bioscience, Inc. | Phase 1 |
| Unknown | Real Time Elastography in Liver Fibrosis NCT01948687 | University of Medicine and Pharmacy Craiova | — |
| Completed | The Association With Peptic Ulcer Disease and Hepatic Vein Pressure Gradient NCT01944878 | Chuncheon Sacred Heart Hospital | — |
| Recruiting | Nottingham Community Liver Biomarkers Cohort NCT02037867 | University of Nottingham | — |
| Completed | Non-invasive Diagnosis of Portal Hypertension With Acoustic Radiation Force Impulse (ARFI) NCT01644656 | VA Connecticut Healthcare System | N/A |
| Completed | To Evaluate the Efficacy of DDB/Garlic Oil in Patients With Elevated Transaminase Chronic Liver Disease NCT02347319 | PharmaKing | Phase 4 |
| Completed | Vitamin D Improves Depression in Liver Patients NCT02359266 | Universität des Saarlandes | N/A |
| Completed | Combination Diagnostic Strategies in NAFLD NCT04384159 | University Hospital, Montpellier | — |
| Terminated | Detection of Hepatocellular Carcinoma (HCC) With Octanoate Breath ID Test Compared to MRI NCT01433016 | Meridian Bioscience, Inc. | Phase 2 |
| Terminated | Predicting Lung Injury From Transfusion in Patients With Liver Disease NCT01756690 | University of Colorado, Denver | — |
| Completed | G-CSF and Erythropoetin in Survival of Patients With Decompensated Liver Disease NCT01384565 | Institute of Liver and Biliary Sciences, India | Phase 3 |
| Withdrawn | Increlex Treatment of Children With Chronic Liver Disease and Short Stature NCT01314508 | University of California, Los Angeles | N/A |
| Unknown | Hepatocyte Matrix Implant Study Indonesia NCT01335568 | Baermed | Phase 1 |
| Completed | Detection of Liver Fibrosis With Magnetic Resonance Imaging (MRI) NCT01600105 | Bachir Taouli | Phase 4 |
| Unknown | ¹³C-Methacetin Breath Test (MBT) Methodology Study NCT01205074 | Hadassah Medical Organization | Phase 2 / Phase 3 |
| Completed | Evaluation of Liver Fibrosis Staging With Acoustic Radiation Force Impulse Elastography NCT01283230 | Yonsei University | — |
| Terminated | Ultrasound Method to Measure Fibrosis of the Liver in Children NCT02086708 | Massachusetts General Hospital | N/A |
| Unknown | Non-Invasive Evaluation of Fibrosis and Steatosis in Chronic Hepatopathy NCT01246388 | Tischendorf, Jens, M.D. | — |
| Unknown | Efficacy and Safety of Ursodeoxycholic Acid (UDCA) Added to the DPP-4 Inhibitor in People With Type 2 Diabetes NCT01337440 | Kanazawa University | Phase 4 |
| Completed | Sonoelastography: Ultrasound Method to Measure Liver Fibrosis NCT01747772 | Massachusetts General Hospital | N/A |
| Completed | Effect of Probiotics in Treatment of Minimal Hepatic Encephalopathy (MHE) and Health Related Quality of Life NCT01008293 | CD Pharma India Pvt. Ltd. | Phase 2 / Phase 3 |
| Completed | Colesevelam Versus Placebo in Cholestatic Pruritus NCT00756171 | Foundation for Liver Research | Phase 2 / Phase 3 |
| Completed | BreathID 13C-Methacetin Breath Test for Detecting Cirrhosis NCT00736840 | Meridian Bioscience, Inc. | Phase 3 |
| Terminated | Eltrombopag To Reduce The Need For Platelet Transfusion In Subjects With Chronic Liver Disease And Thrombocyto NCT00678587 | GlaxoSmithKline | Phase 3 |
| Terminated | Hypovitaminosis D and an Inadequate PTH Response in Chronic Liver Disease Patients NCT00599352 | Rajib Bhattacharya, MD | N/A |
| Completed | Relative-dose-response Test (RDR) Adaptation for Chronic Liver Disease NCT01634698 | Universidade Federal do Rio de Janeiro | N/A |
| Completed | Preoperative Oral Supplementation With Branched-Chain Amino Acids (BCAA) Improves Postoperative Quality of Lif NCT00945568 | Kochi University | N/A |
| Completed | Genetic Polymorphisms of Interleukin-1B and TNF-A and HBV-Related Hepatocellular Carcinoma NCT00629486 | Kaohsiung Medical University Chung-Ho Memorial Hospital | N/A |
| Unknown | Genetic Polymorphisms of Interleukin-10 and TNF-α on Outcome of HCV-Related Chronic Liver Disease NCT00630006 | Kaohsiung Medical University Chung-Ho Memorial Hospital | N/A |
| Withdrawn | Comparison of the Quantiferon®-TB GOLD (in Tube) Assay With Tuberculin Skin Testing for Detecting Latent Tuber NCT00424684 | University of Pittsburgh | N/A |
| Completed | Polymorphisms of Fibrosis-Relating Genes on Outcome of HCV-Related Chronic Liver Disease NCT00629603 | Kaohsiung Medical University Chung-Ho Memorial Hospital | N/A |
| Unknown | Genetic Polymorphisms of TNF-α Promoter and HBV Genotype on Outcome of HBV-Related Chronic Liver Disease NCT00629668 | Kaohsiung Medical University Chung-Ho Memorial Hospital | N/A |
| Completed | Comparison of Quantiferon-TB Gold Assay With Tuberculin Skin Testing in Patients With Chronic Liver Disease NCT00402402 | University Health Network, Toronto | Phase 4 |
| Completed | Different PEG-interferon and Ribavirin Schedules for Chronic Hepatitis C in the Real Clinical Practice. NCT01195181 | Azienda Ospedaliera di Padova | Phase 4 |
| Completed | Exploring the Comorbidity Between Mental Disorders and General Medical Conditions NCT03847753 | University of Aarhus | — |
| Completed | Study to Evaluate Efficacy and Safety of PENNEL Capsule in the Patients With Chronic Liver Disease NCT01393678 | PharmaKing | Phase 3 |
| Completed | Study to Evaluate Efficacy, Safety and Tolerability of PENNEL Capsule in the Patients With Chronic Liver Disea NCT01393665 | PharmaKing | Phase 2 |