NCT02086708

Ultrasound Method to Measure Fibrosis of the Liver in Children

Sonoelastography: Ultrasound Method to Measure Fibrosis of the Liver in Children

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: Massachusetts General Hospital · Academic / Other
• Sex: All
• Age: 1 Year – 21 Years
• Healthy volunteers: Not accepted

Summary

HYPOTHESIS: The investigators hypothesize that sonoelastography (SE) provide accurate quantitative measurements that can be used to stage liver fibrosis in pediatric patients with chronic liver disease. Specific Aims: To measure liver stiffness with sonoelastography in pediatric and adolescents with suspect diffuse liver disease who will undergo nonfocal liver biopsy as part of their routine clinical care.

Conditions

• Chronic Liver Disease
• Non-Alcoholic Fatty Liver Disease
• HCV Coinfection
• HBV
• Drug-Induced Liver Injury

Interventions

Type	Name	Description
DEVICE	Shear Wave sonoelastography	Shear Wave Sonoelastography as a ultrasound technique to measure liver fibrosis is performed on patients scheduled for non-focal liver biopsy. Results are compared with pathological score of fibrosis from liver biopsy.

Timeline

• Start date: 2010-06-01
• Primary completion: 2015-03-01
• Completion: 2015-03-01
• First posted: 2014-03-13
• Last updated: 2017-02-01
• Results posted: 2017-02-01

Locations

1 site across 1 country: United States