| Recruiting | HBV Reactivation in Immunocompromised Patients (REANT STUDY) NCT07529171 | Yaşar Bayındır, MD | — |
| Not Yet Recruiting | Prospective Cohort Study on PEG-IFN-α-2b in Improving Clinical Cure Rate of Pediatric Patients With Chronic He NCT07231276 | Nanfang Hospital, Southern Medical University | Phase 4 |
| Recruiting | Changes in Bile Acids and Microbiota in Patients With Hepatitis D Treated With Bulvertide NCT07429864 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Recruiting | Clinical Performance Evaluation of MagIA IVD-MD Multiplex Testing (HIV/HBV/HCV/Syphilis) NCT07170748 | MagIA Diagnostics | — |
| Not Yet Recruiting | Real-world Study on Liver Cancer Risk in Chronic Hepatitis B Patients With Family History of Liver Cancer NCT07007286 | Peking University First Hospital | — |
| Not Yet Recruiting | A Real-World Study of Antiviral Therapy in Children With Chronic Hepatitis B NCT06926647 | Beijing 302 Hospital | — |
| Not Yet Recruiting | Non-interventional Study to Assess the Number of People With Untreated/Unknown HBV + HDV and HCV in South-East NCT06834178 | Vanessa Stadlbauer-Koellner, MD | — |
| Recruiting | Phase 1b, Open-label Study of Tune-401 to Assess Safety, PK and PD in Adults With Chronic Hepatitis B NCT06671093 | Tune Therapeutics, Inc. | Phase 1 |
| Not Yet Recruiting | Impact of Hepatitis B Immunoglobulins in Patients With Chronic Hepatitis B on Hepatocellular Carcinoma - a Pro NCT05293158 | Medical University of Graz | N/A |
| Not Yet Recruiting | Current Situation of Health Care in Women With HBV or HCV Infection NCT06579313 | Ruijin Hospital | — |
| Not Yet Recruiting | Antiviral Therapy in Infants With HBV Infection NCT06503796 | Beijing 302 Hospital | Phase 4 |
| Recruiting | Rapid T-cell Analysis Test in Patients With Chronic HBV and HBV/HDV Disease NCT06372990 | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | — |
| Recruiting | The TRIple Elimination Model Of Mother-to-child Transmission Program (TRI-MOM) NCT05951751 | Institut de Recherche pour le Developpement | N/A |
| Unknown | Viral Immunity in Solid Organ Transplant Recipients: Monitoring Of The Response To Hepatitis B Booster Vaccina NCT06307808 | University Hospital, Grenoble | — |
| Not Yet Recruiting | Predictive Value of HBV pgRNA on Long-term Outcomes in Hepatitis B Patients Treated With Antiviral Therapy NCT05965388 | Wen-hong Zhang | — |
| Recruiting | Study on the Treatment of Hepatitis B Virus(HBV) Infected Individuals With Peginterferon α-2b Combined With NA NCT06746701 | Xiangya Hospital of Central South University | — |
| Unknown | The Efficacy and Safety of Rifaximin Treatment NCT05786859 | Sun Yat-sen University | EARLY_Phase 1 |
| Recruiting | Use of Blood Biomarkers for the Early Diagnosis of Hepatocellular Carcinoma (HCC) NCT05781568 | Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis | — |
| Not Yet Recruiting | Nivolumab/Ipilimumab and Chemotherapy Combination in Advanced NSCLC Patients With HIV, HBV, HCV and Long Covid NCT05597800 | Universita di Verona | Phase 2 |
| Unknown | Single-cell RNA Sequencing Resolves the Regulatory Role of HBV on the Hepatocellular Carcinoma Immune Microenv NCT05677724 | Fubing Wang | — |
| Unknown | Evaluation of Intradermal Hepatitis B Vaccine After IMIQUIMOD's Application, in Cirrhotics Who Did Not Respond NCT05028322 | Central Hospital, Nancy, France | Phase 2 |
| Enrolling By Invitation | Prophylactic Entecavir for HBV Reactivation in Past HBV Infected Patients With Hematopoietic Stem Cell Transpl NCT04942886 | Seoul St. Mary's Hospital | N/A |
| Unknown | The Efficacy of Prophylactic TAF for HBsAg-positive Patients Receiving bDMARDs NCT05001672 | Taipei Veterans General Hospital, Taiwan | Phase 4 |
| Terminated | HCV, HBV, HIV Testing During Consultation With Anesthesiologist NCT04286347 | Assistance Publique - Hôpitaux de Paris | N/A |
| Unknown | Tenofovir Alafenamide for HBV Prophylaxis in Post Orthotopic Liver Transplant NCT05063071 | Fudan University | Phase 4 |
| Completed | Relationships Among Inflammation, Physical and Mental Health in Subjects With Chronic Inflammatory Physical Di NCT05125458 | University of Campania Luigi Vanvitelli | — |
| Unknown | Tenofovir Alafenamide for HBV Prophylaxis in HBV(-) Liver Transplant Recipients With HBcAb+ Donors NCT04703465 | RenJi Hospital | N/A |
| Unknown | Predictive Models of Hepatic Decompensation and Survival Outcomes in Pediatric Patients With Cirrhosis NCT05181332 | West China Hospital | — |
| Completed | Specific Anti-HBV Vaccine Response After Vaccination in Patients Requiring Anti-CD20 Monoclonal Antibodies NCT04519710 | Centre de Recherches et d'Etude sur la Pathologie Tropicale et le Sida | N/A |
| Recruiting | Stratified vs Routine Prophylaxis in Living Kidney Transplantation From HBsAg+ Donors to HBsAg- Recipients NCT04562051 | West China Hospital | — |
| Unknown | Tenofovir Alafenamide in HBV Related Decompensated Liver NCT04683341 | Kaohsiung Medical University Chung-Ho Memorial Hospital | Phase 4 |
| Unknown | Entecavir and Tenofovir Versus Entecavir in Lymphoma Patients With Positive HBV DNA NCT04539119 | Ruijin Hospital | Phase 3 |
| Unknown | The Impact of Tenofovir Alafenamide on Profiles of Body Weight and Metabolic Features in Chronic Hepatitis B P NCT04886336 | National Cheng-Kung University Hospital | — |
| Unknown | A Clinical Study of APG-1387 in Combination With Entecavir in Patients With Chronic Hepatitis B NCT04568265 | Ascentage Pharma Group Inc. | Phase 2 |
| Recruiting | Access HBV Assays - European Union (EU) Clinical Trial Protocol - NCT04904835 | Beckman Coulter, Inc. | — |
| Terminated | Evaluating the Safety and Efficacy of Inarigivir in Non-cirrhotic Treatment Naive Subjects Infected With Hepat NCT04059198 | F-star Therapeutics, Inc. | Phase 2 |
| Completed | Clinical Study of hUC-MSCs Treating Decompensated Liver Cirrhosis With HBV NCT05442437 | Zhongnan Hospital | EARLY_Phase 1 |
| Unknown | A Perspective Study of the Antiviral Efficacy and Safety of Switching to TAF Treatment in CHB Adults With Subo NCT04034368 | The First Hospital of Jilin University | Phase 4 |
| Unknown | A Study of AARC Standards on Diagnosis and Treatment of Patients With HBV-ACLF in China (AARC China Study) NCT04054037 | Qin Ning | — |
| Terminated | Evaluating the Safety and Efficacy of Inarigivir in Non-cirrhotic, Hepatitis B e Antigen-negative Subjects Inf NCT04023721 | F-star Therapeutics, Inc. | Phase 2 |
| Terminated | Evaluating the Effects of Inarigivir on Immune Response and Viral Markers in Chronic Hepatitis B Patients NCT03932513 | F-star Therapeutics, Inc. | Phase 2 |
| Unknown | Mechanism of DCs Dysfunction in Chronic HBV Infection NCT03753308 | University Hospital, Grenoble | — |
| Completed | A Randomized, Double-Blind Trial of Antroquinonol in Patients With Chronic Hepatitis B NCT03625102 | Golden Biotechnology Corporation | Phase 2 |
| Completed | A Phase 1 Study to Evaluate the Safety and Pharmacokinetics of Entecavir Extended Release (XR) in Healthy Subj NCT03239353 | Aucta Pharmaceuticals, Inc | Phase 1 |
| Completed | Chronic Hepatitis B Virus Clinical Epidemiology in a Representative Sample of Zambian Adults NCT03149627 | University of Alabama at Birmingham | — |
| Active Not Recruiting | Chronic Hepatitis B Virus Infection in Zambia NCT03158818 | University of Alabama at Birmingham | — |
| Terminated | A Study of ALN-HBV in Healthy Adult Volunteers and Non-cirrhotic Patients With Chronic Hepatitis B Virus (HBV) NCT02826018 | Alnylam Pharmaceuticals | Phase 1 |
| Withdrawn | Cost Effective Non Invasive Diagnostic Modalities and Predictive Model for Development and Progression of Fibr NCT02658786 | Institute of Liver and Biliary Sciences, India | — |
| Active Not Recruiting | Liver Fibrosis in Zambian HIV-HBV Co-infected Patients NCT02344680 | University of Alabama at Birmingham | — |
| Completed | A Pilot Study Comparing the Immunogenicity of Fendrix vs. Double-dose Engerix B in HIV-infected Non-responders NCT02434848 | Sheffield Teaching Hospitals NHS Foundation Trust | Phase 2 / Phase 3 |
| Completed | Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate for Treatment of Hepatitis B e Antigen-Negative Hep NCT02836236 | Gilead Sciences | Phase 3 |
| Completed | Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate for Treatment of Hepatitis B e Antigen-Positive Hep NCT02836249 | Gilead Sciences | Phase 3 |
| Completed | Hepatitis B Virus Vertical Transmission From HIV-HBV Co-infected Women NCT02044068 | Hopital Lariboisière | — |
| Completed | Efficacy and Safety of E/C/F/TAF (Genvoya®) in HIV-1/Hepatitis B Co-infected Adults NCT02071082 | Gilead Sciences | Phase 3 |
| Completed | Widespread vs. Selective Screening for Hepatitis B Infection Prior to Chemotherapy NCT01970254 | M.D. Anderson Cancer Center | — |
| Completed | Prevention of Hepatitis B Virus Vertical Transmission by Serovaccination and Tenofovir During Pregnancy NCT02039362 | Hopital Lariboisière | Phase 4 |
| Unknown | Sorafenib Combined With Transarterial Chemoembolization in Treating HBV-infected Patients With Intermediate He NCT01556815 | Shandong Cancer Hospital and Institute | Phase 2 |
| Completed | Prevention for Mother-to-infant Transmission of HBV NCT02312531 | Xi'an Jiaotong University | N/A |
| Completed | Telbivudine Therapy in HBeAg-positive Pregnant Women to Prevent Mother-to-infant Transmission of HBV NCT01637844 | Yi-Hua Zhou | Phase 4 |
| Completed | A Study Evaluating GS-9620 in Treatment Naive Subjects With Chronic Hepatitis B NCT01590641 | Gilead Sciences | Phase 1 |
| Completed | Impact of Hepatitis B Vaccination on HBs Antigenemia NCT03193775 | Zagazig University | N/A |
| Terminated | Ultrasound Method to Measure Fibrosis of the Liver in Children NCT02086708 | Massachusetts General Hospital | N/A |
| Terminated | Eltrombopag To Reduce The Need For Platelet Transfusion In Subjects With Chronic Liver Disease And Thrombocyto NCT00678587 | GlaxoSmithKline | Phase 3 |
| Completed | Safety and Antiviral Activity of Entecavir in Participants With Chronic Hepatitis B Following Monotherapy in O NCT01438424 | Bristol-Myers Squibb | Phase 2 |
| Withdrawn | 'Tenofovir Pulse and Peg Interferon Alpha 2b' Therapy in HBeAg-positive Patients With Normal ALT NCT02454764 | Institute of Liver and Biliary Sciences, India | N/A |