Clinical Trials Directory

Trials / Terminated

TerminatedNCT04023721

Evaluating the Safety and Efficacy of Inarigivir in Non-cirrhotic, Hepatitis B e Antigen-negative Subjects Infected With HBV Virus and Receiving or Stopping Treatment With a NUC Inhibitor

A Phase 2, Exploratory Study Evaluating the Safety and Antiviral Efficacy of Inarigivir Soproxil in Non-cirrhotic, Hepatitis B e Antigen-negative Subjects Infected With Chronic Hepatitis B Virus and Receiving or Stopping Treatment With a Nucleoside/Nucleotide Inhibitor

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
64 (actual)
Sponsor
F-star Therapeutics, Inc. · Industry
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Not accepted

Summary

An open-label, Phase 2, exploratory study to examine the safety and efficacy of inarigivir in non-cirrhotic, hepatitis B e antigen (HBeAg)-negative subjects with chronic HBV infection.

Conditions

Interventions

TypeNameDescription
DRUGInarigivir soproxilInarigivir soproxil 200 mg tablets
DRUGNucleoside/nucleotide (NUC) analogue inhibitorsContinuation of prestudy NUC therapy

Timeline

Start date
2019-06-18
Primary completion
2020-07-16
Completion
2020-07-16
First posted
2019-07-17
Last updated
2020-07-22

Locations

7 sites across 2 countries: Canada, United Kingdom

Source: ClinicalTrials.gov record NCT04023721. Inclusion in this directory is not an endorsement.