Trials / Unknown
UnknownNCT00629668
Genetic Polymorphisms of TNF-α Promoter and HBV Genotype on Outcome of HBV-Related Chronic Liver Disease
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- —
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Accepted
Summary
The prognosis of Hepatitis B virus (HBV)infection varies from minimal progressive liver disease to cirrhosis or hepatocellular carcinoma (HCC).Both viral and host genetic factors contribute to disease severity. Cytokine gene polymorphism has been regarded affecting prognosis of disease. By detecting HBV genotyping and tumor necrosis factor-alpha polymorphism, this study aime to assess their effects and interaction on disease severity of HBV-related chronic liver disease and HCC.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| GENETIC | TNF-alpha and HBV genotype | |
| OTHER | TNF-alpha and HBV genotypes |
Timeline
- Start date
- 2007-01-01
- Completion
- 2007-12-01
- First posted
- 2008-03-06
- Last updated
- 2008-03-06
Locations
1 site across 1 country: Taiwan
Source: ClinicalTrials.gov record NCT00629668. Inclusion in this directory is not an endorsement.