| Not Yet Recruiting | ETSF for Latinx Young Adults with Alcohol Use Disorder NCT06722690 | Tulane University | N/A |
| Not Yet Recruiting | Testing a Music Listening mHealth Intervention for Stress Reduction in Early Recovery (CalmiFy II) NCT07088237 | Washington State University | N/A |
| Not Yet Recruiting | Social Identity Mapping for Adolescent Recovery NCT07474207 | Massachusetts General Hospital | N/A |
| Not Yet Recruiting | OEA for Young Adults With Alcohol Use Disorder NCT07503782 | Medical University of South Carolina | Phase 2 |
| Not Yet Recruiting | Cannabidiol as an Adjunct Treatment for Alcohol Withdrawal and Craving NCT07148843 | Johns Hopkins University | Phase 2 / Phase 3 |
| Not Yet Recruiting | Deaf CBT-TS to Reduce Suicide Risk NCT07279363 | University of Rochester | N/A |
| Not Yet Recruiting | Effectiveness of Nurse-Conducted Brief Intervention (NCBI) Supplemented With Mobile for Preventing Alcohol Use NCT06652802 | University of Pittsburgh | N/A |
| Not Yet Recruiting | Acceptability and Feasibility Study of Non-alcoholic Beverages NCT07451574 | Stanford University | N/A |
| Not Yet Recruiting | Evaluate the Efficacy and Safety of Naltrexone Hydrochloride Implant in Patients With Alcohol Use Disorder NCT07433413 | Shenzhen Sciencare Medical Industries Co., Ltd. | Phase 3 |
| Recruiting | Probenecid Administration for Alcohol Craving and Consumption NCT07118618 | Brown University | Phase 2 |
| Not Yet Recruiting | Imaging Phosphodiesterase 4B (PDE4B) in People With Psychiatric Disorders With Positron Emission Tomography (P NCT07488819 | Yale University | — |
| Not Yet Recruiting | Psilocybin-assisted Therapy for Comorbid Major Depressive Disorder and Alcohol Use Disorder NCT07405606 | Centre for Addiction and Mental Health | Phase 2 |
| Not Yet Recruiting | Online Interventions to Prevent Alcohol Use Disorders NCT07373405 | University of Southern Denmark | N/A |
| Not Yet Recruiting | Tirzepatide Combined With Cognitive-Behavioural Therapy (CBT) for Adults With Alcohol Use Disorder (AUD) and O NCT07292519 | South West Sydney Local Health District | Phase 2 |
| Recruiting | Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 3 Semaglutide NCT07040592 | Yale University | Phase 2 |
| Not Yet Recruiting | Ketamine-Enhanced Therapy for Individuals With Alcohol Use Disorder and Depression: A Pilot Study (KET-DUAL) NCT07247370 | South West Sydney Local Health District | Phase 1 / Phase 2 |
| Not Yet Recruiting | High Intensity Alternating Current Stimulation as a Neuromodulation Therapy for Alcohol Use Disorder: A Pilot NCT07227545 | Shanghai Mental Health Center | N/A |
| Recruiting | Recovery Through Inhibitory Learning, Self-Efficacy Building, Problem Solving, and Community Building NCT07217795 | University of Rhode Island | N/A |
| Recruiting | Study of Tirzepatide for Recovery and Alcohol Use Management NCT06727331 | Brigham and Women's Hospital | Phase 2 |
| Recruiting | Alcohol and the Social Brain: An Alcohol-Administration Hyperscanning Study Employing a Within-Subject Design NCT07125534 | University of Illinois at Urbana-Champaign | N/A |
| Recruiting | The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD) NCT06070649 | Yale University | Phase 1 |
| Recruiting | Effect of Sublingual Formulation of Dexmedetomidine Hydrochloride (HCl) (BXCL501) - Outpatient Study NCT06335407 | Pharmacotherapies for Alcohol and Substance Use Disorders Alliance | Phase 1 |
| Not Yet Recruiting | Brexanolone to Target Concurrent PTSD and Stress Induced Alcohol Use in Veterans: A Dose Finding Study NCT06580444 | Pharmacotherapies for Alcohol and Substance Use Disorders Alliance | Phase 2 |
| Recruiting | Web-based Alcohol- or Cocaine-specific Inhibition Training in Adolescents and Young Adults With Substance Use NCT07071779 | University of Bern | N/A |
| Recruiting | iTBS for Alcohol Use Disorder NCT06696365 | Nicholas Balderston, PhD | N/A |
| Recruiting | Suvorexant for Treatment of AUD and PTSD NCT06679062 | Pharmacotherapies for Alcohol and Substance Use Disorders Alliance | Phase 2 |
| Not Yet Recruiting | Assessing the Impact of Deep TMS Neuromodulation on Neural Circuits Associated With Alcohol Use Disorder NCT06949423 | Stanford University | N/A |
| Recruiting | Ketamine and Neurofeedback as Combined Therapeutic Interventions to Target Glutamatergic Neurotransmission in NCT06969937 | Dr. med. Marcus Herdener | Phase 2 |
| Recruiting | Psilocybin With Psychological Support (Psi-PS) for Military Veterans and First Responders With Co-occurring PT NCT06853912 | Nathan Brashares Sackett | Phase 2 |
| Recruiting | Developing a Music Listening mHealth Intervention for Stress Reduction in Early Recovery NCT07052318 | Washington State University | — |
| Active Not Recruiting | RECLAIM STUDY: A Phase 2 Evaluating the Efficacy and Safety of Pemvidutide in the Treatment of Alcohol Use Dis NCT06987513 | Altimmune, Inc. | Phase 2 |
| Recruiting | Renewed Recovery: a Pilot Test of a Web-Based Mindfulness-Based Relapse Prevention Continuing Care Interventio NCT06987526 | University of Georgia | N/A |
| Recruiting | Metabolome and Gut Microbiome Changes During Smoking Cessation in Long-term Drug Therapy in a Therapeutic Comm NCT06803706 | Sigmund Freud PrivatUniversitat | N/A |
| Active Not Recruiting | Transcranial Ultrasound Stimulation as a Neuromodulation Therapy for Craving and Relapse Behaviors in Alcohol NCT06867224 | Shanghai Mental Health Center | N/A |
| Recruiting | LHC-CIDI-5 in Hong Kong NCT06804525 | The University of Hong Kong | — |
| Recruiting | Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics NCT06624137 | Yale University | — |
| Recruiting | Diclofenac Dose Response Study NCT06636227 | University of Maryland, Baltimore | Phase 1 |
| Recruiting | Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms NCT06484075 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 1 / Phase 2 |
| Terminated | A Study to Investigate the Safety and Efficacy of TMP-301 Compared to Placebo in Adult Patients With Alcohol U NCT06648655 | Tempero Bio, Inc. | Phase 2 |
| Recruiting | Combining a Smartphone App With Medications to Manage Heavy Drinking NCT06303778 | VA Office of Research and Development | N/A |
| Recruiting | Baclofen for Anxiety and Alcohol Use Disorder (AUD): an Open Label Study NCT06835907 | Universitair Ziekenhuis Brussel | N/A |
| Recruiting | Role of Pavlovian Mechanisms for Control Over Substance Use NCT06701487 | Technische Universität Dresden | — |
| Recruiting | Influence of Mavoglurant on Alcohol Craving and Drinking in Heavy Drinkers NCT06136195 | Yale University | Phase 1 |
| Not Yet Recruiting | LSD Treatment for Persons With Alcohol Use Disorder NCT05474989 | Felix Mueller | Phase 2 |
| Completed | Research on the Heart-Brain Coupling Mechanisms and Interventions for Emotional Inhibitory Control Deficits in NCT07036055 | Shanghai Mental Health Center | N/A |
| Recruiting | Assessing Habitual, Goal-Directed, and Pavlovian Influences in Alcohol Use Disorder NCT06701500 | Technische Universität Dresden | — |
| Recruiting | A Randomised Controlled Trial of N-acetylcysteine for the Management of Alcohol Use Disorder NCT05408247 | University of Sydney | Phase 4 |
| Active Not Recruiting | Psilocybin for Treatment of Alcohol Use Disorder: a Feasibility Study NCT04718792 | Anders Fink-Jensen, MD, DMSci | Phase 2 |
| Active Not Recruiting | Ibudilast for Treating Alcohol Use Disorder NCT05414240 | University of Pennsylvania | Phase 2 |
| Completed | Brain Network Modulation and Alcohol Use NCT04828577 | Virginia Polytechnic Institute and State University | N/A |
| Recruiting | The Oklahoma Parent-Child Assistance Program NCT05534568 | University of Oklahoma | N/A |
| Completed | The Anchor Study: Digitally Delivered Intervention for Reducing Problematic Substance Use NCT04925570 | Woebot Health | Phase 2 |
| Completed | Records for Alcohol Care Enhancement NCT05492942 | Boston Medical Center | N/A |
| Recruiting | Attentional Control Training for Treating Alcohol Use Disorder NCT05102942 | University of Southern Denmark | N/A |
| Completed | Non-invasive Brain Stimulation of the Prefrontal Cortex in Substance Use Disorders NCT05471154 | Universitair Ziekenhuis Brussel | N/A |
| Completed | Examining the Effectiveness of Deep TMS in Veterans With Alcohol Use Disorder NCT04927364 | VA Palo Alto Health Care System | N/A |
| Unknown | Mobile Rewarding Activity Centered Treatment NCT05064228 | University of Central Florida | N/A |
| Recruiting | Pharmaceutically-Enhanced Reinforcement for Reduced Alcohol and Smoking NCT05181891 | Washington State University | Phase 2 |
| Unknown | The Efficacy and Neurobehavioural Mechanism of Cannabidiol (CBD) for Alcohol Dependence NCT05387148 | South West Sydney Local Health District | Phase 2 |
| Completed | AAT-App Outpatient Trial NCT05120856 | Turning Point | N/A |
| Completed | Feasibility and Effects of Activity Trackers Among Alcohol Users Receiving In-patient Treatment for Alcohol Us NCT06629493 | University of Oviedo | N/A |
| Recruiting | The Zonisamide and Reinforcement for Reducing Alcohol Use (ZARRA) Study NCT05134857 | Washington State University | Phase 2 |
| Completed | Human Laboratory Study of ASP8062 for Alcohol Use Disorder NCT05096117 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Not Yet Recruiting | Neurobiological Effects of Transcranial Direct Current Stimulation Treatment in Alcohol Use Disorder NCT04897295 | ITAB - Institute for Advanced Biomedical Technologies | N/A |
| Completed | Medication Development in Alcoholism: Suvorexant Versus Placebo NCT04229095 | The Scripps Research Institute | Phase 2 |
| Completed | Effect of Sublingual Formulation of Dexmedetomidine HCl (BXCL501) - Alcohol Interaction Study NCT04827056 | Pharmacotherapies for Alcohol and Substance Use Disorders Alliance | Phase 1 |
| Completed | Pilot: Digital Therapeutic vs Education for the Management of Problematic Substance Use NCT04974645 | Woebot Health | N/A |
| Enrolling By Invitation | Relationship Between Brain and Heart Glucose Metabolism in Alcohol Use Disorder NCT05015881 | University of Pennsylvania | Phase 2 / Phase 3 |
| Recruiting | Comparison of the Effectiveness of Two Psycho-physical Interventions: Mindfulness Based Relapse Prevention (MB NCT04598399 | Centre Hospitalier Universitaire de Nīmes | N/A |
| Completed | Smartphone-Based Intervention for Sleep Disturbance in Individuals Recovering From Alcohol Use Disorder NCT06108115 | HealthRhythms, Inc. | N/A |
| Completed | Study of DCR-AUD in Healthy Volunteers NCT05021640 | Dicerna Pharmaceuticals, Inc., a Novo Nordisk company | Phase 1 |
| Completed | Mental Imagery Intervention for Alcohol Craving NCT04958655 | King's College London | N/A |
| Completed | Alcohol Telemedicine Consultation in Primary Care (ATC) NCT05252221 | Kaiser Permanente | N/A |
| Unknown | Dynamics of Risk Perception and Risk Behavior in Alcohol Use Disorder and Schizophrenia NCT04985786 | University of Konstanz | N/A |
| Recruiting | MPFC Theta Burst Stimulation as a Treatment Tool for Alcohol Use Disorder: Effects on Drinking and Incentive S NCT04998916 | Medical University of South Carolina | N/A |
| Unknown | Modification of Cue Reactivity by Neurofeedback in Human Addiction NCT04366505 | Central Institute of Mental Health, Mannheim | N/A |
| Unknown | Sleep and Emotional Reactivity in Alcohol Use Disorder NCT04979507 | SRI International | N/A |
| Completed | Michigan SPARC Trial NCT04861792 | Kaiser Permanente | N/A |
| Unknown | Brief Intervention and Fibroscan for Harmful Drinkers Presenting to the Emergency Department NCT05720247 | Nottingham University Hospitals NHS Trust | N/A |
| Completed | Measuring Beliefs and Norms About Persons With Alcohol Use Disorder NCT04832321 | Massachusetts General Hospital | N/A |
| Active Not Recruiting | Factors Predicting Outcome in Group Treatment of Alcohol Use Disorders (AUDs) NCT04822987 | The Hospital of Vestfold | — |
| Recruiting | Cue Effects in Human Addiction: Pavlovian to Instrumental Transfer NCT05992272 | Charite University, Berlin, Germany | — |
| Active Not Recruiting | Comprehensive Process Model of AA-related Behavior Change NCT04618653 | University of New Mexico | — |
| Recruiting | Alpha-1 Blockade for Alcohol Use Disorder (AUD) NCT04135846 | Brown University | Phase 2 |
| Terminated | Impulsivity and Alcohol Response NCT03736343 | University of Florida | EARLY_Phase 1 |
| Completed | Cognitive Rehabilitation Through Personalized Virtual Reality and Paper-and-pencil Interventions in the Alcoho NCT04639895 | Universidade da Madeira | N/A |
| Terminated | A Critical Illness Recovery Navigator for Alcohol NCT03059082 | University of Colorado, Denver | N/A |
| Completed | NAC for Treating Comorbid PTSD and SUD NCT02911285 | Medical University of South Carolina | Phase 2 |
| Completed | Brain Inflammation and Function in Alcoholism NCT02233868 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | EARLY_Phase 1 |
| Completed | A Randomized, Double-blind Placebo-Controlled Pharmacogenetic Study of Topiramate in European-American Heavy D NCT02371889 | University of Pennsylvania | Phase 2 |
| Completed | Volitional Dysfunction in Self-control Failures and Addictive Behaviors NCT04498988 | Technische Universität Dresden | — |
| Completed | Evaluation of the Efficacy of Sodium Oxybate in the Long-term Maintenance of Abstinence in Alcoholic Patients NCT04648423 | Laboratorio Farmaceutico Ct S.r.l. | Phase 4 |