NCT05181891

Pharmaceutically-Enhanced Reinforcement for Reduced Alcohol and Smoking

• Status: Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 205 (estimated)
• Sponsor: Washington State University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Using a randomized controlled trial (RCT), the goal of this study is to evaluate the ability of evidence based behavioral treatment (contingency management: CM) to significantly decrease alcohol use and cigarette smoking among treatment-seeking smokers with an alcohol use disorder (AUD) who have initiated pharmacotherapy (varenicline; VC) for smoking cessation.

Detailed description

This randomized, placebo-controlled trial to determine the effectiveness of contingency management for reducing alcohol use and cigarette smoking among adults who want to quit or reduce their co-addiction. Contingency management is a powerful and cost-effective technique that has been used successfully for decades to promote abstinence from benzodiazepines, cocaine, tobacco, etc. Contingency management, and a non-contingent control condition will be used combined with varenicline (VC) and manualized counseling in the form of module videos.

Conditions

• Alcohol Use Disorder (AUD)
• Nicotine Use Disorder

Interventions

Type	Name	Description
BEHAVIORAL	Contingency Management	Incentives for submitting negative-alcohol urine samples
BEHAVIORAL	Non-contingent control	Incentives for submitting urine samples

Timeline

• Start date: 2022-07-11
• Primary completion: 2026-05-01
• Completion: 2026-05-01
• First posted: 2022-01-06
• Last updated: 2024-06-25

Locations

1 site across 1 country: United States