Trials / Completed
CompletedNCT04568395
Acute Effects of TCIG vs ECIG in PLWH
Acute Impact of Switching From Tobacco Cigarettes to E-Cigarettes in People Living With HIV
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 37 (actual)
- Sponsor
- University of California, Los Angeles · Academic / Other
- Sex
- All
- Age
- 21 Years – 45 Years
- Healthy volunteers
- Not accepted
Summary
Randomized controlled trial of acute use of electronic cigarette or tobacco cigarette on parameters of ventricular repolarization and inflammation/oxidative stress.
Detailed description
On separate days, participants will undergo 3 different exposures: an acute e-cigarette exposure, an acute tobacco cigarette exposure, and a sham (empty e-cigarette) control . Before and after the acute exposure, participants will have blood drawn for inflammation/oxidative stress markers and undergo a 5-minute ECG recording.
Conditions
- E Cigarette Use
- Vaping
- Smoking
- Tobacco Smoking
- Nicotine Use Disorder
- Qt Interval, Variation in
- HIV I Infection
- Oxidative Stress
- Inflammation
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | TCIG | Use a TCIG |
| OTHER | ECIG | Use an ECIG |
| OTHER | sham control | Use a sham control (empty ECIG) |
Timeline
- Start date
- 2020-10-01
- Primary completion
- 2023-05-08
- Completion
- 2023-05-08
- First posted
- 2020-09-29
- Last updated
- 2023-10-04
Locations
2 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT04568395. Inclusion in this directory is not an endorsement.