| Not Yet Recruiting | Parents Helping Parents for Youth Vaping Cessation NCT07207850 | University of Nebraska | N/A |
| Not Yet Recruiting | Sex Differences in E-Cigarette Perception NCT07398976 | Yale University | N/A |
| Recruiting | Effects of a Low Nicotine Standard and Tobacco Prices on Illegal Cigarette Purchasing NCT07161050 | Virginia Polytechnic Institute and State University | N/A |
| Not Yet Recruiting | The Development and Evaluation of a Culturally Grounded ENDS Intervention for Rural Hawaiian Youth NCT06929520 | University of Hawaii | N/A |
| Recruiting | A Trial of Varenicline for E-cigarette Cessation NCT07040566 | Yale University | Phase 2 |
| Completed | Effects of E-Cigarette Use Among Young Egyptian Adults NCT07422415 | Mansoura University Hospital | — |
| Completed | Tobacco Product Susceptibility and Substitutability by Rurality and Alcohol Use NCT07010601 | Mark J Rzeszutek, PhD | N/A |
| Recruiting | An Online Intervention to Reduce E-cigarette Use and Susceptibility to Smoking in Young Adults NCT06129123 | University of Southern California | N/A |
| Not Yet Recruiting | Impact of Aversive Warnings on E-Cigarette Cessation NCT05892445 | University of California, San Diego | Phase 3 |
| Recruiting | Noncombustible Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers NCT06372899 | Abramson Cancer Center at Penn Medicine | N/A |
| Recruiting | Concurrent vs. Sequential Cessation of Dual Cigarette and E-cigarette Use NCT06027840 | Yale University | Phase 1 |
| Recruiting | Adapting an Intervention for Vaping in Young Veterans NCT06196489 | Veterans Medical Research Foundation | N/A |
| Completed | Incentive-based and Media Literacy Informed Approaches to Improve Vaping Cessation NCT05586308 | University of Nebraska | N/A |
| Recruiting | Sex Differences in the Vascular Effects of E-cigarette Use NCT06159608 | Anna Stanhewicz, PhD | EARLY_Phase 1 |
| Recruiting | Evaluation of the Electronic Cigarette Withdrawal Syndrome NCT06066996 | Johns Hopkins University | EARLY_Phase 1 |
| Completed | Developing E-liquid Product Standards (Sweet Spot Study) NCT05864586 | Ohio State University Comprehensive Cancer Center | N/A |
| Recruiting | Vape-Free Text-Messaging: Pilot Study NCT05906082 | Jovan Gwon, PhD, RN, FIAAN | N/A |
| Recruiting | Novel Pulmonary Imaging of Lung Structure and Function in E-cigarette Smokers NCT04616313 | Western University, Canada | — |
| Completed | Vaper to Vaper: A Multimodal Mobile Peer Driven Intervention to Support Adolescents in Quitting Vaping NCT05140915 | University of Massachusetts, Worcester | N/A |
| Enrolling By Invitation | Evaluation of the Be Vape Free Curriculum of the Tobacco Prevention Toolkit NCT05493982 | Stanford University | N/A |
| Unknown | Smoking Prevention Program in Poland NCT05488743 | Wroclaw Medical University | — |
| Completed | Evaluating E-Cigarette Nicotine Form, Concentration, and Flavors Among Youth NCT05458895 | Ohio State University Comprehensive Cancer Center | N/A |
| Withdrawn | Impact of New Product Standards for JUUL Among Dual JUUL/Combusted Cigarette Users NCT04179617 | Duke University | N/A |
| Completed | BIDI Stick ENDS Abuse Liability and Puffing Topography Assessment NCT05072925 | BIDI Vapor | N/A |
| Unknown | Attentional Bias Modification Training for E-cigarette Users NCT05112562 | University of Wisconsin, Milwaukee | N/A |
| Completed | Middle School Cluster Randomized Controlled Trial (RCT) to Evaluate E-Cigarette Prevention Program: CATCH My B NCT04843501 | The University of Texas Health Science Center, Houston | N/A |
| Completed | Acute Effects of TCIG vs ECIG in PLWH NCT04568395 | University of California, Los Angeles | N/A |
| Completed | PACE Vape Messaging Study NCT04450537 | University of Vermont | N/A |
| Completed | The Acute Effects of E-cigarette Inhalation on Vascular Function, Microcirculation and Thrombosis NCT04175457 | Karolinska Institutet | N/A |
| Completed | Effects of E-Cigarettes in Menthol Smokers NCT05949034 | University of Southern California | N/A |
| Completed | E-Cigarette Effects on Markers of Cardiovascular and Pulmonary Disease NCT03863509 | University of Wisconsin, Madison | — |
| Unknown | Feasibility of PET/CT to Detect the Oral/Pulmonary Distribution of Nicotine Following E-cigarette Use NCT03491059 | University of Cincinnati | Phase 4 |
| Completed | Switching to E-Cigarettes After Type 2 Diabetes Diagnosis and Health Outcomes NCT07414355 | Samsung Medical Center | — |