NCT05864586

Developing E-liquid Product Standards (Sweet Spot Study)

Nicotine Concentration and Forms: Differential Appeal to Smokers Versus Non-Smokers

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 150 (actual)
• Sponsor: Ohio State University Comprehensive Cancer Center · Academic / Other
• Sex: All
• Age: 21 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The Sweet Spot Study aims to evaluate the effect of e-liquids with nicotine varying in freebase (FB) levels and concentrations on the appeal of electronic cigarettes (ECs) in young adult EC users with minimal/no history of smoking and older adult smokers.

Conditions

• Nicotine
• Nicotine Vaping
• E-cigarette Use

Interventions

Type	Name	Description
BEHAVIORAL	Vaping study EC A	Vaping two puffs using the study EC device
BEHAVIORAL	Vaping study EC B	Vaping two puffs using the study EC device
BEHAVIORAL	Vaping study EC C	Vaping two puffs using the study EC device
BEHAVIORAL	Vaping study EC D	Vaping two puffs using the study EC device
BEHAVIORAL	Vaping study EC E	Vaping two puffs using the study EC device
BEHAVIORAL	Vaping study EC F	Vaping two puffs using the study EC device
BEHAVIORAL	Vaping study EC G	Vaping two puffs using the study EC device
BEHAVIORAL	Vaping study EC H	Vaping two puffs using the study EC device
BEHAVIORAL	Vaping study EC I	Vaping two puffs using the study EC device
BEHAVIORAL	Vaping study EC J	Vaping two puffs using the study EC device

Timeline

• Start date: 2023-05-30
• Primary completion: 2024-02-26
• Completion: 2024-02-26
• First posted: 2023-05-18
• Last updated: 2025-04-10
• Results posted: 2025-04-10

Locations

1 site across 1 country: United States