| Not Yet Recruiting | Antibiotic Prophylaxis After Simple Tooth Extraction in Immunosuppressed Patients With Autoimmune Rheumatic Di NCT07275580 | University of Sao Paulo General Hospital | Phase 4 |
| Not Yet Recruiting | Surgeons' Prediction of Dental Surgery Complications and the Influence of Patient Characteristics: Development NCT07461324 | University of Copenhagen | — |
| Not Yet Recruiting | Is Cross-linked Hyaluronic Acid a Biologic Alternative for Alveolar Ridge Preservation? NCT07496437 | Medical University of Vienna | N/A |
| Not Yet Recruiting | Reduced Time Interval for Implant Placement After Extraction Socket Preservation Using the Vega Plus Implants NCT07484685 | Universidad Catolica Santiago de Guayaquil | N/A |
| Recruiting | Evaluation of Stem Cell Exosomes Versus Platelet-Rich Fibrin in Tooth Extraction Socket Healing NCT07508033 | Al Salam University | Phase 1 / Phase 2 |
| Withdrawn | Ridge Preservation Following Tooth Extraction NCT05485194 | University of Maryland, Baltimore | N/A |
| Recruiting | Wound Healing Following Tooth Extraction and Ridge Preservation Using OsteoGen® NCT07154693 | The University of Texas Health Science Center at San Antonio | N/A |
| Not Yet Recruiting | Periodontal Regeneration at the Distal Site of Second Molars After the Extraction of Lower Included Third Mola NCT07059247 | Universidad Complutense de Madrid | Phase 4 |
| Not Yet Recruiting | Diode Laser Photocoagulation With Immediate Implant Placement NCT07044895 | Hams Hamed Abdelrahman | N/A |
| Recruiting | Efficacy and Safety Evaluation Study of Implants With Periodontal Ligament NCT07302581 | OrganTech, Inc. | N/A |
| Withdrawn | Immediate Implant Placement Using Volume-Stable Collagen Matrix Combined With rhPDGF-BB NCT06038695 | I-Ching Wang | N/A |
| Active Not Recruiting | Using Different Biomaterials to Preserve Bone After Tooth Extraction NCT07394738 | Inonu University | N/A |
| Enrolling By Invitation | Effect of AV Distraction and Acuapoint Stimulation in Pediatric Extraction on Pain and Anxiety NCT07371442 | Mansoura University | N/A |
| Completed | Infiltration Anesthesia vs. Block Anesthesia NCT06766981 | Sinan A. Shwailiya | N/A |
| Not Yet Recruiting | Evaluation of Antibiotic Administration Following Tooth Extraction NCT06502288 | Chittagong Medical College | N/A |
| Recruiting | Effects of Tranexamic Acid Irrigation on Impacted Third Molar Surgery NCT06806241 | Bezmialem Vakif University | — |
| Active Not Recruiting | Effect of Two Incision Techniques on Soft and Hard Tissue Outcomes in Immediate Implant Placement in Class II NCT07020767 | Ain Shams University | N/A |
| Recruiting | Combination Therapy Effect of Laser on Wound Healing and Bone Regeneration of Dental Sockets NCT06552936 | Sharif Medical Research Center | N/A |
| Completed | Efficacy of Artificial Intelligence-Generated Music Therapy in Reducing Dental Anxiety Among Adults Undergoing NCT06998979 | University of Coimbra | N/A |
| Completed | An Immediate Implant Will be Placed Using the MiniNaviDent System and Static Guide. A Postoperative CBCT Scan NCT07380360 | Ain Shams University | N/A |
| Not Yet Recruiting | A New Syndesmotomy Technique for Tooth Extractions to Preserve the Alveolar Bone NCT06612684 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | N/A |
| Completed | Ridge Preservation With FDBA (Freeze Dried Bone Allograft) Using Dexamethasone vs. Saline NCT06556095 | The University of Texas Health Science Center at San Antonio | EARLY_Phase 1 |
| Recruiting | Assessing Levels of Fear and Anxiety and Monitoring Wound Healing Among Patients Who Are About to Undergo Wisd NCT06473922 | Assaf-Harofeh Medical Center | — |
| Enrolling By Invitation | IMMEDIATE IMPLANT With Different Types of Membranes NCT06657651 | Mansoura University | N/A |
| Unknown | Bovine-derived Xenograft With or Without L-PRF for Alveolar Ridge Preservation After Tooth Extraction: a Rando NCT06172114 | Mohammed Bin Rashid University of Medicine and Health Sciences | N/A |
| Enrolling By Invitation | Alternatives to Dental Opioid Prescribing After Tooth Extraction NCT06275191 | Douglas Oyler | N/A |
| Completed | Cortical Lamina for Alveolar Ridge Preservation NCT07231874 | ARDEC Academy | N/A |
| Completed | Multi-Modal Education to Improve Compliance, Knowledge Retention & Anxiety After Dental Extractions NCT07191132 | Universiti Teknologi Malaysia | N/A |
| Enrolling By Invitation | Treating Children With Extensive Dental Needs NCT06863103 | Malmö University | — |
| Completed | Comparison of Intraligamentary Anesthesia With the Inferior Alveolar Nerve Block for the Extraction of Mandibu NCT06611865 | Hamza Zia Ahmed | N/A |
| Completed | IMMEDIATE IMPLANT With Different Types of Membrane NCT07396350 | Mansoura University | N/A |
| Unknown | Efficacy of Computer Controlled Intraosseous Anesthesia in Pediatric Dental Patients NCT06245161 | Alexandria University | N/A |
| Completed | Injectable Platelet-rich Fibrin and Advanced Platelet-rich Fibrin With Xenograft on the Socket Preservation of NCT06936358 | Hams Hamed Abdelrahman | N/A |
| Completed | Application Of Dentapen In Dental Local Infiltration Anesthesia NCT07431801 | Son Hoang Le | N/A |
| Recruiting | Comparison of Two Collagen Membranes for Bone Augmentation Around Dental Implants Restored with Monolithic Zir NCT06724783 | Dr. med. dent. Malin Strasding | Phase 4 |
| Completed | On Adequacy of Referrals to Oral and Maxillofacial Surgery NCT05845437 | Region Skane | — |
| Unknown | Ridge Preservation Using Different Techniques NCT05892016 | Tri-Service General Hospital | N/A |
| Terminated | Ultrasound-based Imaging to Detect Early Changes of Hard and Soft Tissue Around Immediately Placed Implants Wi NCT05330702 | University of Iowa | N/A |
| Unknown | Platelet Rich Fibrin (PRF) in Socket Preservation Technique NCT06173492 | University of Naples | N/A |
| Completed | Immediate Implant Loading After Ridge Preservation Using Autogenous Dentin Graft and Beta-Tricalcium Phosphate NCT07324083 | Soaad Tolba Mohammed Tolba Badawi | N/A |
| Completed | Clinical and Radiographic Evaluation of Topical Vitamin D on Immediate Dental Implants NCT06806423 | Suez Canal University | N/A |
| Unknown | Treatment of Alveolar Osteitis: Traditional or Regenerative? NCT05615272 | University of Dublin, Trinity College | N/A |
| Active Not Recruiting | Autogenous Dentin Derived Barrier Membrane Versus Collagen Membrane NCT06615362 | Mansoura University | N/A |
| Unknown | Remimazolam vs Midazolam Cognitive and Motor Recovery After Intravenous Conscious Sedation for Dental Extracti NCT05220462 | Guy's and St Thomas' NHS Foundation Trust | Phase 3 |
| Completed | Comparative Study of Immediate Single Unit Implants in Early Loading Protocols, With or Without Photobiomodula NCT05106855 | University of Santiago de Compostela | N/A |
| Active Not Recruiting | Peri-implant Tissues on the Galimplant Anti-rotational Slim Abutment. NCT05118815 | University of Santiago de Compostela | N/A |
| Completed | Effect of Low Power Laser in the Pain After Lower Tooth Extraction NCT05255731 | University of Santiago de Compostela | N/A |
| Completed | Assessing the Effect of Virtual Reality Gamification on Anxiety and Pain Management During Extraction of MIH-a NCT06964451 | Rasa Mladenovic | N/A |
| Completed | Evaluation of β-tricalcium Phosphate/Calcium Sulfate Versus Allografts NCT05708196 | Mansoura University | N/A |
| Unknown | Alveolar Ridge Preservation in Molar Extraction Sockets With an Open Healed Collagen Membrane: A Randomized Cl NCT04802148 | National Taiwan University Hospital | N/A |
| Unknown | Vestibular Socket Therapy in Immediate Implants With Grafting Materials NCT04957654 | Mohamed Mofreh Hamada Hamed | N/A |
| Active Not Recruiting | Soft Tissue Volume Changes After Immediate Implants With Two Different Techniques NCT04803110 | Aula Dental Avanzada | N/A |
| Completed | Physics Forceps vs Conventional Forceps in Extraction of Mandibular Molars NCT04875650 | Melaka Manipal Medical College | N/A |
| Completed | Platelet Rich Fibrin and Concentrated Growth Factors on Osseointegration of Immediate Implants NCT05101954 | Hams Hamed Abdelrahman | N/A |
| Completed | Assessment of DAFILON® Suture Material in Oral Surgery (Mucosal Sutures) NCT04390620 | Aesculap AG | — |
| Active Not Recruiting | The Indications of First Molar Extraction at Tufts University, School of Dental Medicine NCT04705181 | Tufts University | — |
| Completed | De-Implementing Opioids for Dental Extractions NCT03584789 | HealthPartners Institute | N/A |
| Completed | Vestibular Socket Therapy With and Without Bone Grafting NCT04930497 | Hams Hamed Abdelrahman | N/A |
| Completed | The Clinical and Biological Effects of Leucocyte and Platelet-rich Fibrin (L-PRF) on Post-extraction Sockets H NCT03985033 | The European Research Group on Periodontology (ERGOPerio) | N/A |
| Completed | Effect of Immersive Virtual Reality on Pain in Different Dental Procedures in Children NCT06794788 | King Abdullah University Hospital | N/A |
| Completed | Childrens' Experiences of Pain in Conjunction With Tooth Extraction - a Grounded Theory Study NCT04064853 | Malmö University | — |
| Completed | Vestibular Extraction Technique (VET): a Novel Atraumatic Extraction Technique NCT04990999 | Hams Hamed Abdelrahman | N/A |
| Completed | Pre-emptive Analgesic Administration in Primary Tooth Extraction NCT03786029 | Tishreen University | Phase 2 / Phase 3 |
| Active Not Recruiting | Plasma Rich in Growth Factors in Post-extraction Sockets NCT03943680 | Universidad de Granada | N/A |
| Active Not Recruiting | Resorbable vs Non-resorbable Bone Substitute at Immediate Post-extractive Single Implants NCT07047131 | Marco Esposito | Phase 3 |
| Completed | Comparison of the Efficacy and Safety of Two Homologous Active Principles for Local Dental Anesthesia NCT04166890 | Universidad de Antioquia | Phase 4 |
| Completed | Prediction Model of Cardiac Risk for Dental Extraction in Elderly Patients With Cardiovascular Diseases NCT03211312 | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | — |
| Completed | A Clinical Study on the Efficacy and Safety of Lando® Absorbable Collagen Membrane in Oral Bone Repair NCT03464786 | Shenzhen Lando Biomaterials Co., Ltd. | N/A |
| Completed | A 14 Weeks Longitudinal Study to Investigate the Effect of Leukocyte- Platelet Rich Fibrin Plug on the Quality NCT03487718 | Firas Al Yafi | N/A |
| Completed | Immediate Implant Placement in Fresh Extraction Sockets and Delayed Implants in Healed Sockets. NCT04346706 | Saint-Joseph University | N/A |
| Terminated | Tranexamic Acid To Reduce Bleeding in Patients Treated With New Oral Anticoagulants Undergoing Dental Extracti NCT03413891 | Universitaire Ziekenhuizen KU Leuven | Phase 4 |
| Completed | Is the Direct Inferior Alveolar Nerve Block Required for Third Lower Molar Extraction? NCT03443726 | University of Barcelona | N/A |
| Unknown | Evaluation of Anesthetic Efficacy in Extraction on Mandibular Molars NCT03106168 | University of Sao Paulo | N/A |
| Completed | Comparison of Two Intravenous Drug Combinations for Ambulatory Oral & Maxillofacial Surgery NCT06867068 | Albert Einstein College of Medicine | Phase 1 |
| Completed | Antibiotic Therapy in Erupted Tooth Extractions NCT04082598 | Antonio Barone | Phase 4 |
| Unknown | The Effect of Alveolar Ridge Preservation After Tooth Extraction in the Posterior Maxilla NCT02952209 | NYU College of Dentistry | N/A |
| Completed | Ridge Preservation With New Class of Osteoplastic Materials NCT02155764 | I.M. Sechenov First Moscow State Medical University | Phase 2 |
| Completed | Acupuncture on Anxiety and Inflammatory Events Following Surgery of Mandibular Third Molars NCT03545022 | Federal University of the Valleys of Jequitinhonha and Mucuri | N/A |
| Completed | A Volumetric Analysis of Soft and Hard Tissue Healing for Ridge Preservation and Socket Seal After Tooth Extra NCT02844569 | University of North Carolina, Chapel Hill | N/A |
| Completed | Combination of Platelet-Rich Fibrin and Calcium Sulfate in Socket Augmentation NCT03851289 | University of Malaya | N/A |
| Completed | Esthetic Outcomes of Immediately Placed Implants Receiving Immediate Provisionalization and Delayed Restoratio NCT01925339 | University of Michigan | N/A |
| Completed | Ridge Preservation Using FDBA and a Collagen Wound Dressing in Molar Sites NCT03191448 | The University of Texas Health Science Center at San Antonio | N/A |
| Completed | Efficacy of Platelet Rich Plasma (PRP) on Mouth Opening and Pain After Surgical Extraction of Mandibular Third NCT04452734 | Foundation University Islamabad | N/A |
| Completed | Anxiety and Hemodynamic Changes in Third Molar Extraction After Patient Education NCT07018115 | Ummugulsum Coskun | N/A |
| Completed | Evaluating the Effectiveness of Axiostat Hemostatic Dressing Material Versus Conventional Method of Hemostasis NCT03108365 | Axio Biosolutions Pvt. Ltd. | N/A |
| Completed | Histological Comparison of Ridge Preservation Using Mineralized FDBA Alone Versus a Combined Mineralized-Demin NCT01924390 | The University of Texas Health Science Center at San Antonio | N/A |
| Completed | Safety, Tolerability and Efficacy Study of TT-173 in Healthy Volunteers After Tooth Extraction NCT01595360 | Thrombotargets Europe S.L | Phase 1 |
| Completed | Ridge Preservation After Tooth Extraction Using Cortical Versus Cancellous Freeze Dried Bone Allograft NCT01588444 | The University of Texas Health Science Center at San Antonio | N/A |
| Completed | A Study to Evaluate the Safety and Efficacy of an Investigational Drug in the Treatment of Postoperative Denta NCT00387140 | Merck Sharp & Dohme LLC | Phase 2 |
| Completed | Capsaicin to Control Pain Following Third Molar Extraction NCT00088686 | National Institute of Dental and Craniofacial Research (NIDCR) | Phase 2 |
| Completed | Pain Pathways in the Brain NCT00078364 | National Institute of Dental and Craniofacial Research (NIDCR) | Phase 2 |
| Completed | Prostanoid Levels After Medication to Prevent Pain Following Third Molar (Wisdom Tooth) Extraction NCT00078104 | National Institute of Dental and Craniofacial Research (NIDCR) | Phase 2 |
| Completed | Rofecoxib and Bupivacaine to Prevent Pain After Third Molar (Wisdom Tooth) Extraction NCT00050362 | National Institute of Dental and Craniofacial Research (NIDCR) | Phase 2 |