NCT05101954

Platelet Rich Fibrin and Concentrated Growth Factors on Osseointegration of Immediate Implants

A Comparative Study Between the Effect of Platelet-rich Fibrin and Concentrated Growth Factors on Osseointegration of Immediate Implants (a Randomized Clinical Trial)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 14 (actual)
• Sponsor: Hams Hamed Abdelrahman · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

This study will involve 14 patients with mandibular premolars indicated for extraction and immediate replacement. The patients will be randomly allocated into two groups and each patient will receive one implant. In Group A, a CGF membrane will be laid in the implant cavity. While in Group B, a PRF membrane will be laid in the implant cavity. Bone graft material will be applied to fill the empty parts of the socket. Resonance frequency measurement will be done using the OSTELL device intraoperatively, at the 1st week and after 3 months. Cone-beam computed tomography will be done preoperatively, immediately following surgery, and after 3 months

Conditions

• Tooth Extraction
• Dental Implants

Interventions

Type	Name	Description
PROCEDURE	Concentrated Growth Factors (CGF)	Concentrated Growth Factors membrane will be laid in the implant cavity. Bone graft material will be applied to fill the empty parts of the socket.
PROCEDURE	Platelet-Rich Fibrin (PRF)	Platelet-Rich Fibrin (PRF) membrane will be laid in the implant cavity. Bone graft material will be applied to fill the empty parts of the socket.

Timeline

• Start date: 2020-10-01
• Primary completion: 2021-08-17
• Completion: 2021-08-17
• First posted: 2021-11-01
• Last updated: 2021-11-01

Locations

1 site across 1 country: Egypt