| Recruiting | ACT Lung Health Intervention: Phase Two NCT06945120 | Dana-Farber Cancer Institute | N/A |
| Recruiting | Respiratory Function and Oxygenation in Smokers and Non-smokers NCT07027956 | Kirsehir Ahi Evran Universitesi | — |
| Completed | Comparison of Postoperative Pulmonary Complications Between Smokers and Nonsmokers NCT06982911 | mehmet özkılıç | — |
| Recruiting | A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free Home NCT06693700 | Memorial Sloan Kettering Cancer Center | N/A |
| Recruiting | The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Maligna NCT06535867 | Memorial Sloan Kettering Cancer Center | — |
| Completed | Tobacco Cessation in Public Housing NCT04889638 | Johns Hopkins University | N/A |
| Recruiting | Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia NCT05660525 | University of Virginia | N/A |
| Recruiting | V+PSF-M for Tobacco Cessation in HIV Care in India NCT05786547 | University of Colorado, Denver | Phase 3 |
| Active Not Recruiting | Process and Effect Evaluation of the KickAsh! Intervention NCT05920772 | University Ghent | N/A |
| Completed | CSD201204 An Actual Use Study of P12 Electronic Nicotine Delivery System Among U.S. Adult Smokers NCT05960305 | RAI Services Company | N/A |
| Unknown | Investigating Exposure to Toxicants From Smoking and Vaping NCT05953220 | King's College London | — |
| Completed | A Brief Digital Screening Tool to Address Tobacco and E-cigarette Use in Pediatric Medical Care NCT05366790 | St. Justine's Hospital | N/A |
| Completed | Nicotine Pharmacokinetics of THS Single Use of a Regular or a Menthol Stick Compared to CIG NCT05789420 | Philip Morris Products S.A. | N/A |
| Completed | Comparison of Saliva Biomarkers in Two Different Geographical Regions of Turkey NCT06809439 | Karabuk University | N/A |
| Enrolling By Invitation | The Next Step in Smoking Prevention: the Reduction of Tobacco Retail Outlets, a Comprehensive Policy Evaluatio NCT05554120 | Maastricht University Medical Center | — |
| Completed | Messages About Reduced Nicotine in Combusted Tobacco Products NCT05506046 | Georgia State University | N/A |
| Completed | Impact of Positive Mental Vs. Physical Health Messaging on Motivation to Stop Smoking NCT06762756 | Katherine Sawyer | N/A |
| Completed | The Effect of Motivational Interviews Based on the Transtheoretic Model on Pregnant Women's Smoking Cessation NCT05173428 | Cumhuriyet University | N/A |
| Completed | Smoking, Stress, and Mobile Technology NCT04838236 | University of Houston | N/A |
| Completed | Contingency Management for Smoking Cessation NCT04982952 | University of California, San Francisco | N/A |
| Terminated | High Dose Bupropion for Smoking Cessation - Pilot Study NCT03326128 | University of Southern California | Phase 2 |
| Completed | Proactive Outreach for Smoking Treatment NCT04988477 | Sandra Japuntich | Phase 2 |
| Unknown | Development and Assessment of a Teacher-led Intervention in Preventing Tobacco Use Among the Youth in Ghana NCT04891939 | Ghana Health Services | N/A |
| Active Not Recruiting | Digitally Enhanced Smoking Cessation for High Risk Smokers NCT04691297 | Dana-Farber Cancer Institute | N/A |
| Withdrawn | Opioids and Smoking Cessation NCT03857139 | University of Houston | Phase 4 |
| Recruiting | Cue Effects in Human Addiction: Pavlovian to Instrumental Transfer NCT05992272 | Charite University, Berlin, Germany | — |
| Completed | Smoking Cessation Pilot for People Living With HIV (PLWH) NCT04808609 | Columbia University | N/A |
| Terminated | PRogetto Salute Parma NCT04282694 | University of Parma | — |
| Completed | Evaluation of Electronic Portal Messaging and Embedded Asynchronous Care on Physician-Assisted Smoking Quit At NCT05172219 | Oklahoma State University Center for Health Sciences | N/A |
| Completed | GeoScan and Remote Geo Smoking Study: Neural and Behavioral Correlates of Smokers' Exposure to Retail Environm NCT04279483 | Abramson Cancer Center at Penn Medicine | N/A |
| Completed | Connecting Alaska Native People to Quit Smoking NCT03645941 | Mayo Clinic | N/A |
| Completed | Examining Brain Responses Linked to Emotion in Individuals Who Smoke Cigarettes NCT04310735 | Penn State University | N/A |
| Completed | Assessment of the Pivot Breath Sensor: Single-Arm Cohort Study NCT04133064 | Jennifer Marler, MD | N/A |
| Completed | Personalized Feedback for Distress Intolerant Smokers NCT03918031 | University of Houston | N/A |
| Completed | PARQuit Smoking Cessation Intervention for Adults With Serious Mental Illness NCT03950427 | University of California, San Francisco | Phase 4 |
| Completed | Version 2 of the Smoking Cessation Smartphone App "Smiling Instead of Smoking" (SiS) NCT03951766 | Massachusetts General Hospital | N/A |
| Completed | Optimizing Smoke-free Residential Housing Policies NCT04791722 | Harvard School of Public Health (HSPH) | N/A |
| Unknown | Harm Reduction for Tobacco Smoking With Support of Tobacco-Replacing Electronic Nicotine Delivery Systems NCT03962660 | University of Washington | N/A |
| Completed | Assessing the Integration of Tobacco Cessation Treatment Into Lung Cancer Screening (LCS) NCT03611881 | Massachusetts General Hospital | Phase 4 |
| Completed | DECIDE: Developing Tools for Lung Cancer Screening Discussion Improvement NCT03891602 | Hackensack Meridian Health | — |
| Completed | Pivot Breath Sensor Performance Study NCT03870022 | Jennifer Marler, MD | N/A |
| Completed | Pivot Breath Sensor Human Factors and Usability Study NCT03835260 | Jennifer Marler, MD | N/A |
| Completed | Effects of Nicotine in Tobacco Smokers NCT03651869 | University of Southern California | Phase 1 |
| Completed | Hollings Cancer Center Varenicline Sampling Study NCT03742154 | Medical University of South Carolina | EARLY_Phase 1 |
| Completed | An Extended Facebook Intervention for Young Sexual and Gender Minority Smokers NCT03553992 | University of California, San Francisco | N/A |
| Completed | Tobacco Cessation Intervention NCT03657511 | Barbara Ann Karmanos Cancer Institute | N/A |
| Completed | Evaluation of an Intensive Individualized Smoking Cessation Program Delivered by Pharmacists NCT03597607 | Memorial University of Newfoundland | N/A |
| Completed | Addictive Potential of LCCs in Dual Users NCT03496077 | UConn Health | N/A |
| Unknown | The Role of Congenital Mucosal Immune System in the Airways of Patients With Chronic Obstructive Pulmonary Dis NCT04061122 | Medical University of Lodz | — |
| Active Not Recruiting | Nicotinic Hepatic Metabolism on Neuroreceptor Substrates of Nicotine Addiction NCT03442413 | University of Pennsylvania | Phase 1 |
| Completed | A Guided Imagery Tobacco Cessation Intervention Delivered by a Quit Line and Website NCT02968381 | University of Arizona | N/A |
| Completed | A Facebook Intervention for Young Sexual and Gender Minority Smokers NCT03259360 | University of California, San Francisco | N/A |
| Completed | Path2Quit Tobacco Intervention For African Americans NCT03524482 | Case Comprehensive Cancer Center | N/A |
| Completed | Identify Biomarkers of Tobacco Exposure and Nicotine Uptake From JUUL 5% in Adult Smokers NCT03463837 | Juul Labs, Inc. | N/A |
| Unknown | Testing a Self-affirmation Intervention for Use in a Mobile Application NCT03405220 | Kent State University | N/A |
| Unknown | Grip&Health: Behavioural Intervention to Reduce Smoking, Stress and Improve Financial Health in Low-SES in Rot NCT03553979 | Erasmus Medical Center | N/A |
| Completed | Effect of Smoking and Periodontal Therapy on Salivary and Gingival Crevicular IL-17 and IL-35 NCT05281848 | Gazi University | N/A |
| Completed | Applying Novel Technologies and Methods to Inform the Ontology of Self-Regulation: Binge Eating and Smoking NCT03353649 | Stanford University | N/A |
| Completed | Personalized Feedback for Smokers With Elevated Anxiety Sensitivity NCT03382093 | University of Houston | N/A |
| Completed | Examination of Low Wattage and High Wattage E-Cigarettes NCT03113136 | Ohio State University Comprehensive Cancer Center | N/A |
| Completed | Helping Poor Smokers Quit NCT03194958 | Washington University School of Medicine | N/A |
| Completed | The Lung Screening, Tobacco and Health Project NCT03200236 | Georgetown University | Phase 3 |
| Completed | Effects of Smoking on Placenta and Lactation NCT06456645 | Celal Bayar University | — |
| Completed | Music to Reduce Use of Smoking in Patients With Schizophrenia NCT03190161 | NYU Langone Health | N/A |
| Completed | Carbon Monoxide Breath Sensor System Performance, Human Factors, and Usability Assessment Conducted in a Singl NCT03148613 | David Utley, MD | N/A |
| Active Not Recruiting | BROnchoalveolar Investigations of Never-smokers With Chronic Obstruction From the Swedish CardioPulmonary bioI NCT03049202 | Karolinska Institutet | — |
| Completed | Smoking Reduction Intervention for Smoking Parents of Paediatric Patients in Hong Kong NCT03879889 | Chinese University of Hong Kong | Phase 4 |
| Completed | The Cardiovascular Impacts of Electronic Cigarettes in Comparison to the Use of Nicotine Replacement Patches NCT03358953 | NHS Greater Glasgow and Clyde | N/A |
| Completed | Pilot Study of Contingency Management for Smoking Cessation NCT03015597 | King's College London | N/A |
| Completed | BRP1602: Evaluation of Technical and Logistical Feasibility to Measure Lung Permeability NCT06105424 | RAI Services Company | N/A |
| Completed | A Health Recommeder System to Tailor Message Preferences in a Smoking Cessation Programme NCT03206619 | University of Seville | — |
| Unknown | MapMySmoke: Smoking Cessation App With Geospatial Capture NCT02932917 | University of St Andrews | Phase 1 |
| Completed | Use of the Motivational Interviewing in the Treatment of Smokers in Groups in Primary Health Care NCT03221010 | Hospital Nossa Senhora da Conceicao | N/A |
| Completed | Proactive Population Health Strategy to Offer Tobacco Dependence Treatment to Smokers NCT03612895 | Massachusetts General Hospital | N/A |
| Unknown | Adverse Airway Effects From Tobacco and E-Cigarettes NCT03251053 | Miami VA Healthcare System | N/A |
| Completed | Financial Incentives for Smoking Treatment NCT02506829 | NYU Langone Health | N/A |
| Completed | Enhancing Smoking Cessation in the Homeless Population NCT01932996 | University of Minnesota | Phase 4 |
| Completed | Let's STOP Now Trial: Smoking in Trauma Orthopaedic Patients NCT02428244 | University of Maryland, Baltimore | N/A |
| Completed | Internet-Based Nonsmoking Program for Postpartum Women NCT02602730 | Oregon Center for Applied Science, Inc. | Phase 2 |
| Active Not Recruiting | An Observational Study on the Natural Course of Chronic Pancreatitis NCT04574297 | Changhai Hospital | — |
| Completed | Post-Market Surveillance of Tobacco Products NCT04255459 | RAI Services Company | N/A |
| Completed | Proactive Tobacco Treatment for Veterans NCT00608426 | US Department of Veterans Affairs | N/A |
| Completed | Bupropion and Cigarette-Related Cues in Smokers NCT03920319 | University of California, Los Angeles | Phase 1 |
| Completed | The Whole Day First Grade Program NCT00257088 | American Institutes for Research | Phase 4 |