NCT04310735

Examining Brain Responses Linked to Emotion in Individuals Who Smoke Cigarettes

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 62 (actual)
• Sponsor: Penn State University · Academic / Other
• Sex: All
• Age: 21 Years – 55 Years
• Healthy volunteers: Accepted

Summary

The study will use functional magnetic resonance imaging and facial coding methods to study individuals who smoke cigarettes. Smoking expectancy (the extent to which one perceives an opportunity to smoke a cigarette) will be manipulated using instructions, and the investigators will examine the effects of this manipulation on two primary endpoints under conditions designed to induce an urge to smoke: (1) brain responses measured using fMRI and (2) subjective affective responses measured using facial coding. Secondary endpoints include self-report measures of the desire to smoke and current affect.

Conditions

• Smoking, Tobacco

Interventions

Type	Name	Description
BEHAVIORAL	Verbal smoking expectancy manipulation	Instructions regarding whether or not participants will have an opportunity to smoke during the experimental session.

Timeline

• Start date: 2019-10-04
• Primary completion: 2023-06-30
• Completion: 2023-11-28
• First posted: 2020-03-17
• Last updated: 2025-03-07
• Results posted: 2025-03-07

Locations

1 site across 1 country: United States