| Recruiting | Role of Transposable Elements in Septic Immune Aging NCT06809868 | University of California, San Francisco | — |
| Recruiting | Treatment Strategy of Human Gamma Globulin on the Therapy for Intensively Ill Children With Inflammatory Storm NCT04850456 | Children's Hospital of Fudan University | — |
| Not Yet Recruiting | Accuracy of Venous Excess Ultrasound (VEXUS) Score Versus Central Venous Pressure in Patients With Severe Seps NCT06586931 | Minia University | — |
| Completed | Does the Phoenix Pediatric Sepsis Prognosis Prediction Scale Work NCT06539884 | Oguz Dursun | — |
| Recruiting | Early Intravenous Hydrocortisone in Sepsis NCT06217939 | Siriraj Hospital | N/A |
| Recruiting | Reducing Empiric VAncomycin Use in Pediatric Suspected Sepsis NCT05975671 | Children's Hospital of Philadelphia | N/A |
| Recruiting | Early Administration of Norepinephrine in Sepsis NCT05836272 | Tunis University | Phase 4 |
| Unknown | The Value of Full-targeted Pathogen Capture Metagenomics Next Generation Sequencing in Etiological Diagnosis o NCT05540808 | Shenzhen Second People's Hospital | — |
| Recruiting | Towards Novel BIOmarkers to Diagnose SEPsis on the Emergency Room NCT06178822 | Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC) | — |
| Withdrawn | Effects of IL-1β and Its Receptor Antagonists in the Treatment of Severe Infection and Inflammatory Storm in C NCT04821414 | Children's Hospital of Fudan University | — |
| Recruiting | Recovery From Acute Immune Failure in Septic Shock by Immune Cell Extracorporeal Therapy NCT05442710 | Artcline GmbH | Phase 2 |
| Completed | Effect of Probiotics on Cytokines in Sepsis in Children NCT05467605 | Cairo University | N/A |
| Recruiting | Assessment for Implementation Methods in Sepsis NCT05491941 | Rhode Island Hospital | N/A |
| Unknown | High-dose Intravenous Vitamin C in Patients With Septic Shock NCT04796636 | Melbourne Health | Phase 1 |
| Completed | Microcirculation Properties of Albumin for Fluid Resuscitation in Septic Shock NCT05357339 | Rachael Cusack | N/A |
| Completed | Early Administration of Vitamin C in Patients With Sepsis or Septic Shock in Emergency Departments NCT04747795 | Universitaire Ziekenhuizen KU Leuven | Phase 3 |
| Unknown | De-resuscitation Informed by Ultrasound for Patients With Sepsis NCT04921319 | The Miriam Hospital | N/A |
| Unknown | Function of Circulating Exosomes in Sepsis-induced Immunosuppression NCT04979767 | University of Kansas Medical Center | — |
| Recruiting | Sepsis: From Syndrome to Personalized Care NCT04203979 | Oslo University Hospital | — |
| Unknown | Vitamin C, Vitamin B1 and Steroid in Sepsis NCT04039815 | Far Eastern Memorial Hospital | Phase 4 |
| Unknown | Early Identification of Sepsis in Children NCT03884595 | Brno University Hospital | — |
| Unknown | Immune Profile of Patients With Sepsis NCT04163705 | Hospital El Cruce | — |
| Unknown | Procalcitonin in Diagnosis of Sepsis in Critically Ill Patient NCT04105400 | Assiut University | — |
| Terminated | EMS Prehospital Blood Culture Collection and Antibiotic Administration: A Two-Phase Pilot Project to Reduce Mo NCT04134624 | HealthPartners Institute | N/A |
| Terminated | The Role of Emergency Neutrophils and Glycans in Postoperative and Septic Patients NCT04117568 | Göteborg University | — |
| Completed | Effects of Endotoxin Absorption and Cytokine Removal Hemofilter on Severe Septic Shock NCT03974386 | National Taiwan University Hospital | N/A |
| Terminated | Recombinant Interleukin-7 (CYT107) to Restore Absolute Lymphocyte Counts in Sepsis Patients NCT03821038 | Revimmune | Phase 2 |
| Completed | As an Early Indicator Biomarker of Prognosis and Mortality in Children With Sepsis and Septic Shock: suPAR NCT04459572 | Ege University | N/A |
| Unknown | Comparison of Balanced Crystalloids and Normal Saline in Septic Patients NCT03685214 | ZhiYong Peng | N/A |
| Unknown | Multiple Biomarkers in ICU Sepsis Patients NCT03802136 | Zhongnan Hospital | — |
| Completed | Is NMES Treatment in Sepsis/ Septic Shock Patients Protective in Development of ICU-AW? NCT04833621 | Ondokuz Mayıs University | N/A |
| Completed | LIPIDS-P Trial Phase I/II Trial NCT03405870 | University of Florida | Phase 1 / Phase 2 |
| Completed | DIAGNOSis of Infection in Emergency Department NCT03708796 | Association pour la Formation l'Enseignement et la Recherche du Service de l'Accueil des Urgences | — |
| Completed | Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in Sepsis. NCT03422159 | Community Medical Center, Toms River, NJ | Phase 2 |
| Unknown | Reducing Elevated Heart Rate in Patients With Severe Sepsis by Ivabradine NCT03367026 | Peking Union Medical College Hospital | N/A |
| Completed | Detecting Sepsis in Patients With Severe Subarachnoideal Hemorrhage NCT05246969 | Goethe University | — |
| Completed | Predict Sepsis; the Predictive Value of Bedside Measures in the Ambulance NCT03249597 | Karolinska Institutet | — |
| Completed | MR-Evaluation of Renal Function In Septic Patients NCT02765191 | Uppsala University | N/A |
| Completed | The Effect pf Goal-directed De-escalation in ARDS on Organ Function and Mortality NCT04508296 | Northern State Medical University | N/A |
| Recruiting | Monocyte Profiles in Critically Ill Patients With Pseudomonas Aeruginosa Sepsis NCT03044223 | University of Ulm | — |
| Unknown | Bispectral Index (BIS) for Classification of Procalcitonin (PCT) Sepsis Grades in Critically Ill Patients With NCT03244293 | Suez Canal University | — |
| Completed | Health Related Quality of Life After Intensive Care for Sepsis, a National Cohort Study. NCT06368336 | Uppsala University Hospital | — |
| No Longer Available | Evaluating the Use of Polymyxin B Cartridge Hemoperfusion for Patients With Septic Shock and COVID 19 NCT04352985 | Spectral Diagnostics (US) Inc. | — |