Trials / Recruiting
RecruitingNCT06809868
Role of Transposable Elements in Septic Immune Aging
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 116 (estimated)
- Sponsor
- University of California, San Francisco · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
The goal of this observational study is to learn about how transposable element levels affect the patient outcomes in sepsis. The main questions it aims to answer is: 1. Do transposable elements prematurely age the immune systems of patients with sepsis? 2. Do transposable elements correlate with increased mortality in patients with sepsis in the ICU? 3. Do transposable elements correlate with increased amount of secondary infections in patients with sepsis in the ICU? Participants will have blood drawn from them but will not be subjected to additional interventions.
Conditions
- Sepsis
- Sepsis and Septic Shock
- Sepsis With Multiple Organ Dysfunction (MOD)
- Sepsis With Acute Organ Dysfunction
- Sepsis, Severe
- Sepsis at Intensive Care Unit
- Sepsis, Severe Sepsis and Septic Shock
- Sepsis, Septic Shock
Interventions
| Type | Name | Description |
|---|---|---|
| GENETIC | RNA and DNA Sequencing | DNA and RNA sequencing will be conducted on both control participants and patients with sepsis who are admitted to the ICU. |
Timeline
- Start date
- 2025-02-14
- Primary completion
- 2028-02-14
- Completion
- 2028-08-14
- First posted
- 2025-02-05
- Last updated
- 2026-01-30
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT06809868. Inclusion in this directory is not an endorsement.