NCT04203979

Sepsis: From Syndrome to Personalized Care

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,950 (estimated)
• Sponsor: Oslo University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a prospective, observational study designed to examine the performance of biomarkers, molecular biological methods and other analysis in blood from patient with suspected sepsis in the Emergency department, as well as identidying novel sepsis endotypes. Around 1500 patients will be enrolled.

Detailed description

The study will prospectively include adult patients (\>18 years) with suspected sepsis admitted to Oslo University Hospital, Ullevål (OUH-Ullevål). Patients admitted to the emergency department and managed by the medical rapid response team or the sepsis rapid response team are considered eligible for inclusion. Informed consent will be collected at the emergency department if possible, or within few days, by a clinical investigator or a study nurse. The investigators aim to include 1500 patients treated by the Sepsis Rapid Response Team or Medical Emergency team for possible sepsis. Patients classified to have had other conditions than sepsis in the post hoc assessment will be used as controls. The inclusion period will be 5 years.

Conditions

• Sepsis Syndrome
• Sepsis
• Sepsis, Severe
• Septic Shock

Timeline

• Start date: 2020-01-06
• Primary completion: 2027-07-31
• Completion: 2027-09-30
• First posted: 2019-12-18
• Last updated: 2026-03-19

Locations

1 site across 1 country: Norway