NCT03685214

Comparison of Balanced Crystalloids and Normal Saline in Septic Patients

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 500 (estimated)
• Sponsor: ZhiYong Peng · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

In this prospective randomized controlled trial, investigators attempt to study the effects of acetated Ringer's solution on the prognosis and renal function of patients with sepsis in intensive care unit compared with normal saline, and provide evidence for current fluid resuscitation strategies for sepsis.

Detailed description

During the study period，either normal saline or acetated Ringer's solution will be assigned as resuscitation fluid to the septic patients meeting the inclusion criteria.It is anticipated that about 500 patients will be enrolled during the study period.

Conditions

• Sepsis
• Acute Kidney Injury
• Septic Shock
• Sepsis, Severe

Interventions

Type	Name	Description
DRUG	0.9% saline	we use 0.9% saline in ICU patients with sepsis for resuscitation fluid.
DRUG	lactated Ringer's solution	we use balanced balanced crystalloids in ICU patients with sepsis for resuscitation fluid.

Timeline

• Start date: 2019-03-01
• Primary completion: 2021-04-01
• Completion: 2021-05-01
• First posted: 2018-09-26
• Last updated: 2019-03-26

Locations

1 site across 1 country: China