Trials / Conditions / Restless Legs Syndrome

Restless Legs Syndrome

182 registered clinical trials studyying Restless Legs Syndrome — 13 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	Tonic Motor Activation (TOMAC) Therapy in Patients With Restless Legs Syndrome and Dopaminergic Augmentation NCT07397247	Noctrix Health, Inc.	N/A
Recruiting	Functional Connectivity of the Interoceptive Network in RLS NCT07001891	University Hospital, Bordeaux	N/A
Active Not Recruiting	Efficacy of Vibration Therapy on Restless Legs Syndrome and Sleep Disturbances Among Patients Undergoing Hemod NCT06889324	Amjed Abdulabbas Shraida	N/A
Active Not Recruiting	Response to an Investigational Device in Patients With Restless Legs Syndrome NCT06866132	Noctrix Health, Inc.	N/A
Completed	Restless Legs Syndrome in Temporomandibular Joint Disorders NCT07292077	Gulseren Demir Karakilic	—
Recruiting	Prevalence and Characteristics of Restless Leg Syndrome in Thai Patients With Parkinson's Disease NCT06684782	Siriraj Hospital	—
Completed	Restless Legs Syndrome and Sleep Quality in Pes Planus NCT07117591	Bozok University	—
Recruiting	Restless Leg Syndrome: Is There a Response to Buddhist Walking Meditation in Hemodialysis NCT06806891	Cairo University	N/A
Recruiting	Blood Changes After Exercise in Restless Legs Syndrome NCT06481176	Stanford University	N/A
Not Yet Recruiting	A Randomized, Placebo-controlled Trial of Prednisone in Refractory Restless Legs Syndrome: a Pilot Study NCT06631300	Scripps Health	Phase 1 / Phase 2
Active Not Recruiting	Benefits of a Cannabidiolic Acid Topical Cream for the Treatment of Restless Leg Syndrome NCT06570941	Synthonics Inc	Phase 1 / Phase 2
Recruiting	Ecological Momentary Assessment in Patients With Restless Legs Syndrome NCT05695963	University Hospital, Bordeaux	N/A
Unknown	Gut Microbiota and Bacterial Translocation in Restless Legs Syndrome NCT05985421	University Hospital, Montpellier	—
Completed	Effect of Progressive Muscle Relaxation Exercises in Menopausal Women Experiencing RLS. NCT06156007	Gazi University	N/A
Active Not Recruiting	A Post-Market Study for Long-Term Effectiveness and Safety of the NTX100 for RLS NCT06076499	Noctrix Health, Inc.	—
Recruiting	The Application of Wide Pulse High Frequency Neuromuscular Electrical Stimulation in Disorders Associated With NCT05908214	University of Lausanne	N/A
Completed	Massage, Oxidative and Antioxidant Enzymes in Hemodialysis Patients With Restless Legs Syndrome(RLS) NCT05787080	Baskent University	N/A
Active Not Recruiting	Treating Leg Symptoms in Women With X-linked Adrenoleukodystrophy NCT05003648	Massachusetts General Hospital	Phase 4
Unknown	The Effect of Vitamin C and E Therapy on Restless Leg Syndrome in Patients With End Stage Renal Disease on Hae NCT05350124	King Abdulaziz University	Phase 3
Suspended	A Proof of Concept, Phase 2, Double-blind, Randomized Trial With d-Methadone Product Versus Placebo NCT04145674	Mauro Manconi	Phase 2
Unknown	Restless Legs Syndrome in People With Neuromyelitis Optica Spectrum Disorder NCT05573711	Dokuz Eylul University	—
Unknown	Pitolisant in Refractory Restless Legs Syndrome NCT05581576	William Ondo, MD	Phase 4
Completed	Impact of Iron Supplementation Treatment on Brain Iron Concentrations NCT04144790	Hugo W. Moser Research Institute at Kennedy Krieger, Inc.	—
Unknown	Sublingual Apomorphine in Refractory Restless Legs Syndrome NCT05529095	William Ondo, MD	Phase 4
Completed	The Effect of Compression Stockings on the Complaints of Pregnant Women With Restless Leg Syndrome NCT05795868	TC Erciyes University	N/A
Completed	Noninvasive Peripheral Nerve Stimulation for Medication-Naive and Medication-Refractory RLS NCT05214963	Noctrix Health, Inc.	N/A
Recruiting	Mainz Register of Patients With Sleep Disorders NCT05321355	Johannes Gutenberg University Mainz	—
Terminated	Treatment of Restless Legs Symptoms With Pramipexole to Improve the Outcomes of Protracted Opioid Withdrawal i NCT04759703	Massachusetts General Hospital	Phase 2 / Phase 3
Completed	Exercise Training Versus Ropinirole in Treating Restless Legs Syndrome Among Hemodialysis Patients NCT06468371	Lahore General Hospital	N/A
Completed	Extension Study Evaluating NTX100 Neuromodulation System for Medication-Refractory Primary RLS NCT05196828	Noctrix Health, Inc.	N/A
Recruiting	Clinical Features Associated With Restless Legs Syndrome. NCT05044520	University Hospital, Montpellier	—
Completed	Efficacy of Suvorexant in Patients With Effectively Treated Restless Legs Syndrome and Persistent Chronic Inso NCT04706091	Massachusetts General Hospital	Phase 4
Completed	Noninvasive Peripheral Nerve Stimulation for Medication-Refractory Primary RLS (The RESTFUL Study) NCT04874155	Noctrix Health, Inc.	N/A
Completed	The Effect of Progressive Muscle Relaxation Exercise Training Given to Pregnant Women With Restless Leg Syndro NCT04853771	Gazi University	N/A
Completed	Noninvasive Peripheral Nerve Stimulation for Restless Legs Syndrome During Opioid Medication Reduction NCT04698343	Noctrix Health, Inc.	N/A
Unknown	Hypnosis and Direct Autonomic Experience Influence on Chronic Symptoms NCT04303143	Inner Group Inc.	—
Completed	Anesthetic Management of Patients With Chronic Sleep Disorders NCT04827329	University Hospital, Montpellier	—
Completed	Investigation of the Effects of Different Exercise Programs in Patients With Restless Legs Syndrome. NCT04711993	Gulhane School of Medicine	N/A
Terminated	Oral Iron Frequency for Childhood Restless Leg Syndrome/Periodic Limb Movement Disorder NCT04610827	Mayo Clinic	Phase 4
Completed	Autonomic Assessment in Patients With Restless Legs Syndrome NCT04906486	Kocaeli Derince Education and Research Hospital	—
Unknown	The Effect of Hot and Cold Water Application on Pregnant Women With Restless Leg Syndrome NCT04786314	TC Erciyes University	N/A
Unknown	The Effect of Magnesium Citrate Supplementation in Restless Legs Syndrome (RLS) NCT04462796	OSF Healthcare System	N/A
Completed	Alpha-lipoic Acid Combined With B Vitamins Shows Promise for Treating Restless Legs Syndrome NCT06324760	Uriach Consumer Healthcare	—
Completed	Investigation of the Effects of Medium Cut-off Dialyzers Versus High-Flux Dialyzers on Clinical and Laboratory NCT05698420	Sanliurfa Mehmet Akif Inan Education and Research Hospital	—
Completed	RCT for Pregabalin in Restless Legs Syndrome in South Korea NCT04161027	Seoul National University Hospital	Phase 3
Completed	Aerobic And Strength Training Exercises For Restless Leg Syndrome In Patients With Diabetes NCT04316052	Riphah International University	N/A
Completed	Efficacy of BIPAMS for Restless Legs Syndrome in Adults With Multiple Sclerosis: A Pilot Study NCT04061681	University of Alabama at Birmingham	N/A
Completed	Advancing Understanding of Transportation Options NCT04141891	University of Colorado, Denver	N/A
Terminated	A Follow-up Study of Rotigotine Patch in Adolescent Subjects With Restless Legs Syndrome NCT03992196	UCB Biopharma SRL	Phase 3
Withdrawn	Impact of Acute Leg Cycling at Various Intensities on RLS Severity in Persons With MS NCT03849001	University of Alabama at Birmingham	N/A
Unknown	Effects of Transcutaneous Vagus Nerve Stimulation in Chronic Pain Patients and Healthy Controls NCT05007743	University Medical Center Goettingen	N/A
Completed	Noninvasive Peripheral Nerve Stimulation for Restless Legs Syndrome NCT04700683	Noctrix Health, Inc.	N/A
Terminated	Pramipexole for Restless Leg Syndrome in Peritoneal Dialysis Patients NCT03817554	Dong Jie	Phase 4
Completed	DIalysis Symptom COntrol-Restless Legs Syndrome Trial NCT03806530	Population Health Research Institute	Phase 3
Terminated	REST Study (CompRESsion Therapy for RLS) NCT03852771	Radial Medical, Inc.	N/A
Terminated	Effectiveness of Ropinirole and Gabapentin for the Treatment of RLS in Patients on Maintenance HD NCT03708237	University of Alberta	Phase 2
Unknown	Treatment of Restless Legs Syndrome With the Hypocretin Antagonist Suvorexant NCT03755310	Diego García-Borreguero, MD, PhD	Phase 2
Active Not Recruiting	Adverse Long-term Consequences of Sleep Disordered Breathing: The Ottawa Hospital (TOH) Sleep Database NCT03834792	Ottawa Hospital Research Institute	—
Terminated	A Study of Rotigotine Patch in Adolescent Subjects With Restless Legs Syndrome of Unknown Cause NCT03728933	UCB Biopharma SRL	Phase 3
Completed	The Effect of Hot Water Application in Pregnant Women With Restless Legs Syndrome: A Randomised Controlled Stu NCT04887103	TC Erciyes University	N/A
Terminated	Clinical Trial Assessing the Efficacy and Safety of BP1.4979 in Restless Legs Syndrome NCT03345953	Bioprojet	Phase 2
Unknown	Treatment of Restless Leg Syndrome (RLS) Augmentation With Ecopipam, a D1 Specific Antagonist NCT03218969	William Ondo, MD	Phase 1 / Phase 2
Recruiting	Analysis of Sympathetic Activity in Willis-Ekbom Disease NCT02929732	University Hospital, Montpellier	N/A
Completed	Treatment of RLS/WED Symptoms Through Sensory Counter-stimulation NCT03249779	Mayo Clinic	N/A
Completed	Cardiovascular Variability, Heart Rate Response, and Electromyogram Power Associated With Periodic Leg Movemen NCT03076541	Centre Hospitalier Universitaire de Saint Etienne	—
Completed	Spinal Cord Stimulation for Restless Legs Syndrome NCT03539081	Marshall Holland	N/A
Enrolling By Invitation	Quality Improvement and Practice Based Research in Neurology Using the EMR NCT02670161	Endeavor Health	Phase 4
Completed	Effects of Progressive Muscle Relaxation Exercises During Pregnancy NCT05851001	Ege University	N/A
Completed	A Study on the Use of the MMF07 Foot Massager and Heat Therapy Treatments for Restless Leg Syndrome NCT02526277	Ariane Park	N/A
Completed	The Effect of Horizant (Gabapentin Enacarbil) on Augmentation NCT02642315	University of Missouri-Columbia	N/A
Unknown	Vitamin D in the Treatment of Primary Restless Legs Syndrome NCT02256215	King Abdulaziz University	Phase 2 / Phase 3
Completed	Infra-slow Oscillations During Sleep NCT02532608	Stephany Fulda	N/A
Completed	Sleep Deficiency and Stroke Outcome NCT02559739	Insel Gruppe AG, University Hospital Bern	—
Unknown	Effects of Gabapentin Enacarbil on Arousals, Heart Rate, Blood Pressure and PLMs in Restless Legs Syndrome NCT02424695	Cleveland Sleep Research Center	Phase 4
Completed	Yoga vs. Education for Restless Legs Syndrome: a Feasibility Study NCT03570515	West Virginia University	N/A
Withdrawn	IV Iron Treatment of Restless Legs Syndrome NCT02484768	Pharmacosmos A/S	Phase 2
Unknown	Apelin in Willis Ekbom Disease NCT02264600	Acibadem University	—
Completed	Pilot Study: Randomized, Placebo-controlled Comparator Trial of IV vs Oral Iron Treatment of RLS With IDA. (IV NCT02499354	Auerbach Hematology Oncology Associates P C	Phase 2
Completed	Switching From Oral Dopamine Agonists to Rotigotine NCT01976871	John Winkelman, MD, PhD	Phase 4
Withdrawn	Butrans for Treatment of Restless Legs Syndrome NCT02138357	Massachusetts General Hospital	Phase 4
Completed	Cranial Electrotherapy for Military Beneficiaries With Restless Legs Syndrome NCT02419014	Tripler Army Medical Center	N/A
Completed	Clinical Observational Study: IBD Patients With Restless-legs-syndrome and Iron Deficiency Syndrome NCT03457571	Charite University, Berlin, Germany	—
Unknown	Targeting Dopamine Therapy in RLS NCT01937169	Tel-Aviv Sourasky Medical Center	N/A
Completed	Autonomic Function and Cardiovascular Risk in Restless Legs Syndrome NCT02025608	Mauro Manconi	Phase 4
Withdrawn	Vasculaire Leg Compression Device for the Treatment of Restless Legs Syndrome - A Prospective Clinical Study NCT01861652	Walter Reed National Military Medical Center	N/A
Recruiting	Executive Dysfunction in Restless Legs Syndrome: Clinical Correlates and Outcome After Therapeutic Management NCT01823354	University Hospital, Montpellier	N/A
Completed	Specified Drug Use-Results Survey of Regnite NCT01887613	Astellas Pharma Inc	—
Completed	Glutamate, Hyperarousal and Restless Legs Syndrome NCT01675323	Johns Hopkins University	—
Completed	Gabapentin Enacarbil (GSK1838262) Adult Restless Leg Syndrome (RLS) Post Marketing Commitment Study NCT01668667	XenoPort, Inc.	Phase 4
Completed	Validation Study for an Unobtrusive Online Sleep Measurement System NCT01633151	Beddit.com Ltd	—
Completed	A Sleep Laboratory Study to Investigate the Safety and Efficacy of the Rotigotine Skin Patch in Subjects With NCT01537042	UCB BIOSCIENCES GmbH	Phase 3
Completed	Rotigotine Effect on All-day Functioning and Quality of Life in Subjects With Moderate to Severe Restless Legs NCT01569464	UCB Pharma	Phase 3
Completed	A Study to Evaluate the Effect of Gabapentin on Cardiac Repolarization in Healthy Volunteers NCT01516372	XenoPort, Inc.	Phase 1
Completed	Dose Escalating Study of Rotigotine in Pediatric Subjects With Restless Legs Syndrome NCT01495793	UCB BIOSCIENCES, Inc.	Phase 2
Completed	Long-Term Follow-Up Study for Safety, Efficacy and Tolerability of Rotigotine in Adolescents With Restless Leg NCT01498120	UCB BIOSCIENCES, Inc.	Phase 2
Completed	Safety and Efficacy Study of IPX159 in Restless Legs Syndrome (RLS) NCT01521663	Impax Laboratories, LLC	Phase 2
Completed	Sleep Disorders Managed and Assessed Rapidly in Transient Ischemic Attack (TIA) and In Early Stroke NCT01528462	Sunnybrook Health Sciences Centre	—
Completed	Effects of Neupro on Cardiovascular Observations in Patients With Restless Legs Syndrome NCT01455012	UCB BIOSCIENCES GmbH	Phase 4
Completed	Drug Drug Interaction Study With Gabapentin Enacarbil and Morphine NCT01476124	XenoPort, Inc.	Phase 1
Completed	Effect on RLS Symptom Severity After Switching to Neupro® in Patients Who Previously Experienced Augmentation NCT01386944	UCB Pharma	—
Terminated	Safety and Efficacy of Rasagiline in Restless Legs Syndrome NCT01192503	University of Virginia	Phase 2 / Phase 3
Completed	Survey on Long-Term Use of BI-Sifrol® Tablets in Patients With Restless Legs Syndrome NCT01174459	Boehringer Ingelheim	—
Withdrawn	12-Week Efficacy And Safety Of Pregabalin In Treating Restless Legs Syndrome (RLS) Subjects NCT01061372	Pfizer's Upjohn has merged with Mylan to form Viatris Inc.	Phase 3
Completed	Altered Brain GABA and Glutamate in Restless Legs Syndrome NCT01109537	Brigham and Women's Hospital	—
Completed	Gabapentin and Risk of Pancreatic Cancer and Renal Cancer (GPRD) NCT01138124	GlaxoSmithKline	—
Completed	Polysomnography Study Of Pregabalin And Pramipexole Versus Placebo In Patients With Restless Legs Syndrome And NCT00991276	Pfizer's Upjohn has merged with Mylan to form Viatris Inc.	Phase 3
Terminated	Clinical Evaluation of Ropinirole IR (Immediate Release) Tablets in Patients Who Are Diagnosed With Symptomati NCT00996944	GlaxoSmithKline	Phase 2
Completed	Restless Legs Syndrome Treatment With Botulinum Toxin NCT00949806	University Hospital, Bordeaux	Phase 2
Completed	Non-interventional Observational Study on the Influence of Pramipexole on Sensory Symptoms of Restless Legs Sy NCT00887289	Boehringer Ingelheim	—
Completed	Suggested Immobilization Test (SIT) Test for Early Detection of Restless Legs Syndrome (RLS) Augmentation - Pr NCT00867893	Johns Hopkins University	—
Terminated	Efficacy and Safety Study of Aplindore in Patients With Restless Legs Syndrome NCT00834327	Neurogen Corporation	Phase 2
Completed	Polysomnography Study of GSK1838262 Extended Release Tablets Versus Placebo in RLS and Associated Sleep Distur NCT00748098	XenoPort, Inc.	Phase 3
Completed	Pramipexole in Out-patients With Idiopathic Restless Legs Syndrome (IRLS) NCT00654498	Boehringer Ingelheim	Phase 3
Unknown	Neuroma Injections to Treat Restless Legs Syndrome - RCT NCT00656110	Lowcountry Infectious Diseases	N/A
Completed	Lyrica Dose Response Study With Restless Legs Syndrome (RLS) Patients NCT00676403	Pfizer's Upjohn has merged with Mylan to form Viatris Inc.	Phase 2
Completed	Study of Vitamin C, Vitamin E and Their Combination to Treat Restless Legs Syndrome in Hemodialysis Patients NCT01125033	Shiraz University of Medical Sciences	Phase 2 / Phase 3
Completed	Bupropion and Restless Legs Syndrome NCT00621517	East Tennessee State University	Phase 2 / Phase 3
Completed	The Effects of Aplindore on the Treatment of Signs and Symptoms of Restless Legs Syndrome NCT00626418	Ligand Pharmaceuticals	Phase 2
Completed	Restless Legs Syndrome in Stroke Patients NCT01967303	Rambam Health Care Campus	—
Completed	Long-term Efficacy and Safety of Gabapentin Enacarbil in Japanese Restless Legs Syndrome Patients NCT02658188	Astellas Pharma Inc	Phase 3
Completed	Safety and Effect of Mirapex(Pramipexole) Tablet Among Korean RLS NCT01170091	Boehringer Ingelheim	—
Completed	Cross-Sectional Study: Prevalence of Restless Legs Syndrome in Patients With Unpleasant Sensations of the Legs NCT00557258	Boehringer Ingelheim	—
Withdrawn	Pregabalin (Lyrica) for the Treatment of Restless Legs Syndrome NCT00584246	University of South Florida	Phase 4
Completed	ASP8825 - Study in Patients With Restless Legs Syndrome NCT00530530	Astellas Pharma Inc	Phase 2
Completed	Sifrol (Pramipexole) Onset of Action and Impact: a 12-weeks Observational Study in Patients With Primary Restl NCT00721279	Boehringer Ingelheim	—
Completed	Clinical Evaluation of Ropinirole CR-RLS ( SK&F101468)Tablets in Restless Legs Syndrome NCT00530790	GlaxoSmithKline	Phase 2
Completed	Long-term Efficacy, Safety and Tolerability of Pramipexole in Patients With Idiopathic Moderate to Severe Rest NCT00472199	Boehringer Ingelheim	Phase 4
Completed	Botulinum Toxin to Treat Restless Legs Syndrome NCT00479154	National Institute of Neurological Disorders and Stroke (NINDS)	Phase 1 / Phase 2
Completed	Simulated Driving Study in Restless Legs Syndrome NCT01332318	XenoPort, Inc.	Phase 2
Completed	Non-interventional Observational Study of Pramipexole in Restless Legs Syndrome: Impact on Quality of Life NCT00539461	Boehringer Ingelheim	—
Completed	Dose-Response and Pharmacokinetics of Gabapentin Enacarbil (GEn [XP13512 / GSK1838262]) in Restless Legs Syndr NCT01332305	XenoPort, Inc.	Phase 2
Completed	Biotin Deficiency and Restless Legs Syndrome NCT02011191	Heidi Moretti, MS, RD	N/A
Completed	12-week Polysomnography Study of Ropinirole Controlled Release for Restless Legs Syndrome NCT00373542	GlaxoSmithKline	Phase 4
Completed	A 6 Week Trial to Study the Efficacy and Safety of a Starting Dose 0.25 mg Pramipexole (Mirapex) in Patients W NCT00375284	Boehringer Ingelheim	Phase 4
Completed	Exercise Training in Dialysis Patients With Restless Legs Syndrome (RLS) NCT00942253	University of Thessaly	Phase 2
Completed	Restless Legs Patient Study On Absorption, Distribution, Metabolism And Excretion Of Ropinirole And The Effect NCT00419692	GlaxoSmithKline	Phase 1
Completed	Efficacy, Safety and Tolerability of Rotigotine Nasal Spray for the Acute Treatment of RLS Symptoms NCT00389831	UCB Pharma	Phase 2
Completed	XP13512 vs. Placebo in Patients With Restless Legs Syndrome. NCT00365352	XenoPort, Inc.	Phase 3
Completed	Phase IV Trial With Pramipexole to Evaluate Safety and Efficacy in Patients With RLS Associated With Mood Dist NCT00356096	Boehringer Ingelheim	Phase 4
Completed	A Phase IV Trial With Pramipexole to Investigate the Effects on RLS Symptoms and Sleep Disturbance in Patients NCT00349531	Boehringer Ingelheim	Phase 4
Completed	The Effects Of Ropinirole On Mood Or Mild Depression In Patients With Moderate To Severe Restless Legs Syndrom NCT00357097	GlaxoSmithKline	Phase 3
Completed	XP13512 (Gabapentin Enacarbil) Extension Study in Patients With Restless Legs Syndrome. NCT00333359	XenoPort, Inc.	Phase 3
Completed	Study to Investigate Pharmacokinetics (PK) of Pramipexole in Pediatric Patients Who Are Individually Optimized NCT02231918	Boehringer Ingelheim	Phase 2
Completed	SWITCH:Restless Legs Patients Switched to Ropinirole From Pramipexole NCT00344994	Augusta University	Phase 4
Completed	REQUIP RLS Post Marketing Surveillance NCT01327339	GlaxoSmithKline	—
Completed	Long-Term Study of Gabapentin Enacarbil (GEn, XP13512) vs. Placebo in Patients With Restless Legs Syndrome. NCT00311363	XenoPort, Inc.	Phase 3
Completed	Observational Study of Sifrol® in Patients With Primary Restless Legs Syndrome (RLS) NCT02248155	Boehringer Ingelheim	—
Completed	A Study To Investigate The Effects Of End Stage Renal Disease And Hemodialysis On The Pharmacokinetics Of Ropi NCT00422994	GlaxoSmithKline	Phase 1
Completed	XP13512 (GSK1838262) Versus Placebo in Patients With Restless Legs Syndrome. NCT00298623	XenoPort, Inc.	Phase 3
Completed	Long-term Study Of Ropinirole In Restless Legs Syndrome NCT00329602	GlaxoSmithKline	Phase 4
Completed	RLS In Adults: Comparing Immediate Release Formulation With Extended Release Formulation Of Ropinirole NCT00314860	GlaxoSmithKline	Phase 3
Completed	Observational Study of Sifrol® in Patients With Primary Restless Legs Syndrome (RLS) NCT02248142	Boehringer Ingelheim	—
Completed	An Extension Trial to Investigate Long-Term Treatment With Transdermal Rotigotine in Idiopathic Restless Legs NCT00263068	UCB Pharma	Phase 3
Unknown	Restless Legs Syndrome Exercise Intervention NCT00258492	Northeastern Ohio Universities College of Medicine	Phase 1 / Phase 2
Completed	Converting From Ropinirole Immediate Release (IR) To Ropinirole Controlled-Release for RLS (Restless Legs Synd NCT00256854	GlaxoSmithKline	Phase 3
Completed	Comprehensive Police Fatigue Management Program NCT00246051	Brigham and Women's Hospital	N/A
Completed	A Sleep Lab Trial to Investigate the Efficacy and Safety of Transdermal Rotigotine in Subjects With Idiopathic NCT00275236	UCB Pharma	Phase 3
Completed	Long-Term Safety Of Ropinirole XR In Patients With Restless Legs Syndrome NCT00355641	GlaxoSmithKline	Phase 3
Completed	Sequential Compression Devices for Treatment of Restless Legs Syndrome NCT00479531	Walter Reed Army Medical Center	Phase 3
Completed	Study of Istradefylline (KW-6002) for the Treatment of Restless Legs Syndrome NCT00199446	Kyowa Kirin, Inc.	Phase 2
Completed	Ropinirole Tablets In Young Patients With Restless Legs Syndrome NCT00140712	GlaxoSmithKline	Phase 1
Completed	Ropinirole XR (Extended Release) In Patients With Restless Legs Syndrome NCT00197080	GlaxoSmithKline	Phase 3
Completed	Sleep Disorders Management, Health and Safety in Police NCT00207285	Brigham and Women's Hospital	N/A
Completed	Three Different Transdermal Doses of Rotigotine in Subjects With Idiopathic Restless Leg Syndrome NCT00136045	UCB Pharma	Phase 3
Completed	Four Different Transdermal Doses of Rotigotine in Subjects With Idiopathic Restless Legs Syndrome NCT00135993	UCB Pharma	Phase 3
Completed	A Clinical Research Study Evaluating Ropinirole Treatment For Restless Legs Syndrome (RLS) NCT00225862	GlaxoSmithKline	Phase 3
Completed	Pramipexole (BI-Sifrol®) Orally Once Daily for 6 Weeks in Patients With Primary Restless Legs Syndrome NCT00152997	Boehringer Ingelheim	Phase 2
Completed	Efficacy and Safety of Pramipexole Compared to Placebo in the Treatment of Restless Legs Syndrome (RLS) NCT00133198	Boehringer Ingelheim	Phase 3
Completed	A Study in Patients Suffering From Idiopathic Restless Legs Syndrome Who Responded to a Preceding, 6-month Tre NCT00152958	Boehringer Ingelheim	Phase 3
Completed	Relationship Between Sensory and Motor Systems in Restless Leg Syndrome NCT00074672	National Institute of Neurological Disorders and Stroke (NINDS)	—
Completed	Iron Sucrose In The Treatment of Restless Legs Syndrome: Safety of Three Dose Regimens as Evaluated by Clinica NCT00895232	American Regent, Inc.	Phase 2
Completed	A Double Blind Crossover Trial of Levetiracetam (Keppra®) and Placebo in the Treatment of Restless Legs Syndro NCT00247364	Sleep Health Centers	Phase 2
Completed	A Clinical Research Study Testing Ropinirole Treatment for Restless Legs Syndrome NCT00363857	GlaxoSmithKline	Phase 3
Completed	Long-term Open-label Trial in Idiopathic Restless Legs Syndrome (RLS) NCT00498186	UCB Pharma	Phase 2
Completed	Assess Efficacy and Safety of the Dopamine Agonist Pramipexole Versus Levodopa / Benserazide (Madopar® DR) in NCT00144209	Boehringer Ingelheim	Phase 3
Completed	Effect of Ropinirole on Spinal Cord Reflexes and Restless Legs Syndrome NCT00051961	National Institute of Neurological Disorders and Stroke (NINDS)	—
Completed	A Study to Determine the Efficacy and Safety of Cabergoline for the Treatment of Patients With RLS NCT00625547	Pfizer	Phase 3
Completed	A Study to Evaluate the Efficacy and Safety of Cabergoline Compared With Placebo for the Treatment of RLS NCT00627003	Pfizer	Phase 3
Completed	Dose Finding Study of Pramipexole (Sifrol) in Patients With Idiopathic Restless Legs Syndrome (RLS) NCT00239486	Boehringer Ingelheim	Phase 2
Completed	Efficacy and Safety of Pramipexole (PPX) in Moderate to Severe Idiopathic Restless Legs Syndrome (RLS) Patient NCT00275457	Boehringer Ingelheim	Phase 3
Completed	Efficacy and Safety Study of Topiramate to Treat Restless Legs Syndrome NCT00200941	Neurocare	Phase 4
Completed	Transdermal Lisuride: a Trial for the Treatment of Patients With Restless Legs Syndrome (RLS) NCT00367822	Axxonis Pharma AG	Phase 3