NCT02264600

Apelin in Willis Ekbom Disease

Oxidative Stress and Apelin Level in Willis Ekbom Disease

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 30 (estimated)
• Sponsor: Acibadem University · Academic / Other
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to assess apelin level in patients with Willis-Ekbom Disease (WED) as known Restless Legs Syndrome (RLS). Cardiovascular complications of WED have been reported in recent studies. Increased oxidative stress is thought to play an important role in cardiovascular complications of WED patients. Apelin is a novel described antioxidant bioactive peptide. The investigators hypothesize that patients with WED have lower plasma apelin level than healthy subjects based on presence of oxidative stress of WED.

Conditions

• Restless Legs Syndrome

Timeline

• Start date: 2014-11-01
• Primary completion: 2015-02-01
• Completion: 2015-04-01
• First posted: 2014-10-15
• Last updated: 2014-10-15