Clinical Trials Directory

Trials / Completed

CompletedNCT00627003

A Study to Evaluate the Efficacy and Safety of Cabergoline Compared With Placebo for the Treatment of RLS

A Double-blind, Randomized, Placebo-controlled Multicenter Efficacy Study for the Treatment of Patients With Restless Legs Syndrome (RLS)

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
43 (actual)
Sponsor
Pfizer · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the efficacy and safety of cabergoline compared with placebo on periodic leg movements (PLMS) arousl index and sleep efficiency in patients with RLS. Also, additional objective and subjective sleep parameters and quality of life will be assessed.

Conditions

Interventions

TypeNameDescription
DRUGCabergolineCabergoline oral tablets administered once daily in the evening: 0.5 mg daily on Days 1 to 3, 1.0 mg daily on Days 4 to 7, 1.5 mg daily on Days 8 to 10, and 2.0 mg daily on Days 11 to 14, followed by a stable dose for an additional 3 weeks
OTHERPlaceboPlacebo oral tablets administered daily for 5 weeks

Timeline

Start date
2002-11-01
Completion
2003-05-01
First posted
2008-02-29
Last updated
2011-04-25

Source: ClinicalTrials.gov record NCT00627003. Inclusion in this directory is not an endorsement.