| Recruiting | Communication Bridge 3 Study NCT06191198 | University of Chicago | Phase 2 |
| Active Not Recruiting | Communication Bridge Pilot Study NCT06211374 | University of Chicago | N/A |
| Recruiting | Educational Support Group Program for Bilingual and Spanish-speaking Carepartners and People With Progressive NCT06511752 | University of Texas at Austin | EARLY_Phase 1 |
| Recruiting | Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia NCT05386394 | Johns Hopkins University | Phase 2 |
| Recruiting | Improving Prognostic Confidence in Neurodegenerative Diseases Causing Dementia Using Peripheral Biomarkers and NCT06529744 | University Health Network, Toronto | — |
| Completed | Transmagnetic Stimulation Pilot in Primary Progressive Aphasia NCT05860647 | HealthPartners Institute | N/A |
| Terminated | Home-based tDCS in Frontotemporal Dementia or Alzheimer's Disease NCT05978804 | Johns Hopkins University | N/A |
| Enrolling By Invitation | Speech-Language Treatment With Remotely Supervised Transcranial Direct Current Stimulation in Primary Progress NCT05901233 | University of Texas at Austin | N/A |
| Enrolling By Invitation | Primary Progressive Aphasia Multicomponent Language Treatment Study NCT06649084 | University of Texas at Austin | N/A |
| Recruiting | Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive NCT05741853 | University of Texas at Austin | N/A |
| Completed | Home-Based Exercise in Primary Progressive Aphasia (HEPPA) NCT06181500 | Montreal Heart Institute | N/A |
| Recruiting | Nabilone for Agitation in Frontotemporal Dementia NCT05742698 | Simon Ducharme, MD | Phase 2 |
| Completed | Long-term Effect of TMS in Primary Progressive Aphasia NCT05842473 | Hospital San Carlos, Madrid | N/A |
| Recruiting | A Multimodal Approach for Clinical Diagnosis and Treatment of Primary Progressive Aphasia, MAINSTREAM ID:34309 NCT05730023 | IRCCS Centro San Giovanni di Dio Fatebenefratelli | N/A |
| Completed | Remotely Supervised Transcranial Direct Current Stimulation (tDCS) for Primary Progressive Aphasia (PPA) NCT05615922 | NYU Langone Health | Phase 2 |
| Recruiting | Enhancing Language Function in Aphasia NCT05443633 | University of Arizona | N/A |
| Recruiting | Targeting Language-specific and Executive-control Networks With Transcranial Direct Current Stimulation in Log NCT03887481 | Johns Hopkins University | N/A |
| Completed | Identification of Graphic Markers of Neurocognitive Disorders (MG) NCT05537688 | Centre integre universitaire de sante et de services sociaux du Centre-Sud-de-l'Île-de-Montréal | — |
| Completed | Better Living With Non-memory-led Dementia NCT05525377 | University College, London | N/A |
| Active Not Recruiting | Treating Primary Progressive Aphasia and Apraxia of Speech Using Non-invasive Brain Stimulation NCT05368350 | The University of Texas at Dallas | N/A |
| Recruiting | Semantic Rehabilitation for Patients With Primary Progressive Semantic Aphasia NCT04957537 | University Hospital, Toulouse | N/A |
| Recruiting | Enhancing Language Function in Primary Progressive Aphasia NCT04920318 | University of Arizona | N/A |
| Completed | Clinical Feasibility of Speech Phenotyping for Remote Assessment of Neurodegenerative and Psychiatric Disorder NCT04939818 | Novoic Limited | — |
| Completed | CB3 Pilot (Communication Bridge: A Person-centered Internet-based Intervention for Individuals With Primary Pr NCT05697380 | University of Chicago | N/A |
| Completed | Treating Primary Progressive Aphasia (PPA) Using tDCS NCT04566731 | University of Pennsylvania | N/A |
| Terminated | Circuitry Assessment and Reinforcement Training Effects on Recovery NCT04290988 | Johns Hopkins University | N/A |
| Completed | Treating Primary Progressive Aphasia (PPA) Using High-definition tDCS NCT04046991 | University of Pennsylvania | Phase 2 |
| Completed | PPA Tele-Savvy: A Pilot Study of an Online Intervention for Caregivers of Persons Living With PPA NCT04412083 | Northwestern University | N/A |
| Completed | rTMS Treatment of Primary Progressive Aphasia NCT04431401 | Peking Union Medical College Hospital | N/A |
| Completed | HDtDCS in Logopenic Variant PPA: Effects on Language and Neural Mechanisms NCT03805659 | Medical College of Wisconsin | N/A |
| Completed | The Effects of a Multimodal Approach for the Treatment of PPA NCT04187391 | IRCCS Centro San Giovanni di Dio Fatebenefratelli | N/A |
| Completed | Rehabilitating and Decelerating Language Loss in Primary Progressive Aphasia With tDCS Plus Language Therapy NCT03728582 | Johns Hopkins University | N/A |
| Completed | Network Modulation in Alzheimer's Disease NCT04045990 | Brigham and Women's Hospital | N/A |
| Completed | Florbetaben PET Imaging in PPA NCT04720001 | University of Chicago | — |
| Recruiting | Longitudinal Multi-Modality Imaging in Progressive Apraxia of Speech NCT01818661 | Mayo Clinic | Phase 4 |
| Completed | Communication Bridge 2 NCT03371706 | University of Chicago | N/A |
| Completed | Transcranial Magnetic Stimulation in Primary Progressive Aphasia NCT03580954 | Hospital San Carlos, Madrid | N/A |
| Recruiting | The Neurobiology of Two Distinct Types of Progressive Apraxia of Speech NCT03313011 | Mayo Clinic | — |
| Active Not Recruiting | Treatment for Speech and Language in Primary Progressive Aphasia NCT04881617 | University of Texas at Austin | N/A |
| Completed | Transcranial Direct Current Stimulation for Primary Progressive Aphasia NCT02928848 | University of Pennsylvania | N/A |
| Completed | More Than a Movement Disorder: Applying Palliative Care to Parkinson's Disease NCT03076671 | University of Colorado, Denver | N/A |
| Completed | Assessment of Hyperphosphorylated Tau PET Binding in Primary Progressive Aphasia and Frontotemporal Dementia NCT02736695 | Mayo Clinic | Phase 1 |
| Completed | Preventing Language Decline in Dementia NCT02541097 | Baycrest | N/A |
| Completed | Early-onset Alzheimer's Disease Phenotypes: Neuropsychology and Neural Networks NCT03153371 | University of California, Los Angeles | — |
| Completed | tDCS Intervention in Primary Progressive Aphasia NCT02606422 | Johns Hopkins University | N/A |
| Withdrawn | Effects of tDCS on Apraxia of Speech in Non-Fluent Primary Progressive Aphasia NCT04486586 | Johns Hopkins University | N/A |
| Completed | Communication Bridge Speech Therapy Research Study NCT02439853 | University of Chicago | N/A |
| Completed | Clinical Evaluation of Florbetapir in Primary Progressive Aphasia NCT04726527 | University of Chicago | — |
| Completed | Performance of AclarusDx™, a Blood-Based Transcriptomic Test for AD, in US Patients Newly Referred to a Memory NCT01465360 | Exonhit | — |
| Completed | PiB PET Scanning in Speech and Language Based Dementias NCT01623284 | Mayo Clinic | Phase 1 |
| Completed | Language Treatment for Progressive Aphasia NCT00957710 | Baycrest | N/A |
| Recruiting | Language in Primary Progressive Aphasia NCT00537004 | Northwestern University | — |