NCT00537004

Language in Primary Progressive Aphasia

Asymmetric Neurodegeneration and Language in Primary Progressive Aphasia

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 500 (estimated)
• Sponsor: Northwestern University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to further define the neurological and linguistic deterioration in primary progressive aphasia.

Detailed description

The Language in Primary Progressive Aphasia (PPA) aims to understand the behavioral, anatomical and physiological changes in people with PPA throughout the course of the illness. The researchers in this study want to increase awareness of PPA, educate others about this unique disorder, and to encourage more research to eventually develop therapies. During the three-day research program, participants will be asked to undergo neuropsychological testing (paper and pencil tests that evaluate cognition), advanced imaging (MRI and PET), cognitive experiments, and other computer and language testing batteries. Participants may be asked to return every two years to complete the same measures. For participants not living near Chicago, IL, flights and accommodations (for both the person with PPA and their companion) will be covered by the study.

Conditions

• Primary Progressive Aphasia

Timeline

• Start date: 2007-05-01
• Primary completion: 2027-04-01
• Completion: 2027-04-01
• First posted: 2007-09-28
• Last updated: 2026-02-27

Locations

1 site across 1 country: United States